Buffalo Bills vs New England Patriots Preview (12/1/22): Betting Odds, Predictions, Depth Chart

The Buffalo Bills are visiting the New England Patriots in Week 13 of the 2022-23 NFL Season. The Bills are coming off a thrilling win against the Lions on Thanksgiving, while the Patriots are coming off a thrilling loss to the Vikings, also on Thanksgiving. This should be an interesting matchup for the AFC East pecking order. Let’s take a look at the odds and make some picks and predictions for this game!

Buffalo Bills vs. New England Patriots Betting Odds

The Buffalo Bills are 5-point road favorites against the New England Patriots and are at -215 on the money line. The over/under is also at 43.5. The spread makes sense because the Bills seem to rebounding well, even if the game is on the road. The over/under also makes sense because these defenses are very good and should be able to limit each sides offense. The spread seems right, but don’t be surprised if it moves down more in favor of the Patriots just because it’s in Foxborough.

Buffalo Bills vs. New England Patriots Prediction

The pick: Bills -5

The Bills were seen as this big juggernaut heading into this season, and they hit a slump recently, but they seem to be over that. The schedule sets up very well for the Bills to end the season, and it starts here in Foxborough. The Buffalo offense is one of the best in the NFL and its headlined by Josh Allen and Stefon Diggs in the passing game, but they need to do more to establish a consistent running game. The running game has been better recently, so it’ll be interesting to see how it does against a very good New England run defense.

The Buffalo defense needs to step up here after Von Miller’s injury. Buffalo has a lot of talent on defense still, but they need to continue to get more healthy after a few other injuries on that side of the ball. On the other side, the Patriots offense has been inconsistent all year. It started when Joe Judge and Matt Patricia were hired to be the two coordinators of the offense. Mac Jones’ injury also didn’t help, but last week against the Vikings was the best game of the year for the offense. It also helps that the game is in Foxborough, where Buffalo has a history of struggling. The Bills are the play here because even without Von Miller, there’s more to like with Buffalo than the Patriots.

Betting Trends

Bills are 6-2 ATS in their last 8 games in December.

Patriots are 3-0-1 ATS in their last 4 games following a straight up loss.

Key Injuries

Buffalo Bills Injuries: DE Greg Rousseau (Ankle) Q, LB Von Miller (Knee) O

New England Patriots Injuries: C Dave Andrews (Thigh) Q, OL Isaiah Wynn (Foot) Q

Key Matchups

Check out the key matchups and mismatches for Buffalo Bills vs New England Patriots below.

Josh Allen vs the Patriots Secondary

Josh Allen has struggled a little recently but he’s still one of the best quarterbacks in the league this year. He has 23 passing touchdowns, 3,183 passing yards, 11 interceptions, and he has a 64% completion percentage on the year. Allen needs to clean up the turnovers he’s had recently, but other than that he’s still playing very well. The Patriots give up 221 passing yards which is very good, and will be a tough matchup for Josh Allen. He needs to have a good game here for the Bills to make a statement on the road in their division.

Mac Jones vs the Bills Secondary

Mac Jones has been inconsistent at best this year, and was also hampered by injuries as well. He has 1,768 passing yards, six passing touchdowns, seven interceptions, and he has a 69% completion percentage on the year. His last game he played was easily the best game he’s played all year, and now the question is if he can sustain it. The Bills allow 240 passing yards a game, so now it’s up to Mac Jones to try and take advantage. Jones needs to have a good game here for the Patriots to stay in this game against the Bills.

Buffalo Bills Depth Chart

QB: Josh Allen
RB1: Devin Singletary
RB2: Nyheim Hines
LWR: Stefon Diggs
RWR: Gabe Davis
SWR: Isaiah McKenzie
TE1: Dawson Knox

New England Patriots Depth Chart

QB: Mac Jones
RB1: Rhamondre Stevenson
RB2: Damien Harris
LWR: Nelson Agholor
RWR: DeVante Parker
SWR: Jakobi Meyers
TE1: Hunter Henry