College Football Week 10 Odds and Lookahead Lines: 4 Bets to Make This Weekend

Week 10 College Football odds and lines are officially posted. Find the most updated College Football odds for Week 10 as well as predictions for marquee matchups such as Washington Vs. USC and Alabama Vs. LSU

Week 10 College Football Odds & Lines

Lookahead College Football odds & Lines for Week 10 – search any school to bring up Week 9 odds

Early College Football Week 10 Bets To Place

Week 10 is highlighted by two primetime blockbusters, with Caleb Williams facing Michael Penix Jr. in a huge test for Washington while Alabama’s defense takes on a dominant LSU offense.

Let’s take a look at the early odds for Week 10 and which bets are worth locking in right now.

Washington (-2.5) vs. USC

Arizona State was a letdown game for Washington, though the Huskies still won behind some excellent defense. The Sun Devils aren’t very good, but they have played their last four opponents (including USC and Colorado) very closely. There’s no shame in a narrow win over Arizona State. There were, however, some real issues on the offensive side of the ball. We know Washington’s offense is much better than that.

With the wake-up call behind them, the Huskies have a chance to pour it on against Stanford this week and re-establish their status as one of the nation’s best teams. A strong showing by Washington’s offense should build more confidence in the unit’s ability to torch a struggling USC defense, even on the road. I’m taking the Huskies today while the line is under a field goal.

Ole Miss (-5) vs. Texas A&M

Texas A&M’s offense hasn’t looked the same since QB Conner Wiegman went down. Max Johnson threw 2 INT against Tennessee last week, and the unit didn’t look right against Alabama the previous week as expected.

As much as South Carolina has struggled late in games this season, it likely won’t be easy for the Aggies to cover a 16.5-point spread against the Gamecocks this week, particularly with the quarterback advantage going to South Carolina. A struggle with the Gamecocks, even if it results in a win, could hurt Texas A&M’s outlook on the road against Ole Miss.

The Rebels are poised for a big win over Vanderbilt this weekend, and their running game has started to regain its 2022 form with the recent success of Quinshon Judkins. As long as Lane Kiffin’s offense shows up as it consistently has at home, Ole Miss can roll past Texas A&M. It wouldn’t be surprising to see this line reach a touchdown leading up to the game.

Oklahoma State (+10) vs. Oklahoma

Oklahoma couldn’t execute late in drives against UCF last weekend, leading to a game that was a bit too close for comfort. The Sooners might have a harder time getting away with that against Kansas, which has found ways to put points on the board regardless of whether Jalon Daniels or Jason Bean is under center (it’ll be Bean vs. Oklahoma).

Could Brent Venables’ team be in for a challenge? If so, don’t be surprised to see this line narrow.

Oklahoma State has totally transformed itself because of the emergence of Ollie Gordon II, who is averaging 176 rushing yards per game over his last four and posted nearly 300 yards against West Virginia. Mike Gundy has his team playing its best football of the season, and with this game in Stillwater a shootout with Oklahoma that ends within single digits seems likely.

The Cowboys face Cincinnati this weekend, so another win should be on tap to strengthen their standing in the eyes of oddsmakers.

Penn State (-12) vs. Maryland

Penn State and Maryland are both poised for resounding wins in Week 9, with the Nittany Lions hosting lowly Indiana and Maryland facing Northwestern. Two big wins might serve to push this line more toward Penn State than Maryland. James Franklin’s team is simply looking to restore credibility after a horrid offensive showing against Ohio State, and a matchup with Indiana is the perfect opportunity to do so.

It’s well-established that Penn State is capable of easily taking down Big Ten teams not named Ohio State and Michigan, and young QB Drew Allar has already proven himself against teams such as Iowa. A return to form for this Penn State team, which boasts a terrific defense, could push this line closer to two touchdowns. At 12 points, I’ll take the Nittany Lions right now.

Dan is a lifelong sports fan and graduate of Boston University. He’s covered several sports on Instagram since he was 12 and now writes about everything from betting trends to breaking news for Lineups.

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