MLB Best Bets and Picks Today: Saturday, June 22

In a Saturday MLB slate that has 15 thrilling matchups, the Atlanta Braves versus the New York Yankees is a game to catch, and we offer best bets for every game here.

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Today’s Best Bets and Picks

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Tigers vs. White Sox Picks

Matchup Info & How to Watch

  • When: 1:10 PM ET
  • Where: Comerica Parkin Detroit, Michigan
  • TV Channel: NBCS-CHI
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Tigers 6, White Sox 4
  • Moneyline Pick: Tigers (-165) over the White Sox (+140)
  • Total Pick: Over (9)

Head to BetMGM to bet on Tigers vs. White Sox and more MLB games!

Starters & Team Records

  • Tigers Starting Pitcher: Kenta Maeda (2-4, 6.00 ERA)
  • White Sox Starting Pitcher: Drew Thorpe (1-1, 5.02 ERA)
  • Records: Tigers (35-41), White Sox (21-57)

Cardinals vs. Giants Picks

Matchup Info & How to Watch

  • When: 2:15 PM ET
  • Where: Busch Stadiumin St. Louis, Missouri
  • TV Channel: NBCS-BA
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Cardinals 5, Giants 4
  • Moneyline Pick: Cardinals (-115) over the Giants (-105)
  • Total Pick: Over (8.5)

Head to BetMGM to bet on Cardinals vs. Giants and more MLB games!

Starters & Team Records

  • Cardinals Starting Pitcher: Miles Mikolas (6-6, 4.68 ERA)
  • Giants Starting Pitcher: Jordan Hicks (4-4, 3.24 ERA)
  • Records: Cardinals (38-37), Giants (36-41)

Cubs vs. Mets Picks

Matchup Info & How to Watch

  • When: 2:20 PM ET
  • Where: Wrigley Fieldin Chicago, Illinois
  • TV Channel: SNY
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Cubs 5, Mets 4
  • Moneyline Pick: Cubs (105) over the Mets (-125)
  • Total Pick: Under (11)

Head to BetMGM to bet on Cubs vs. Mets and more MLB games!

Starters & Team Records

  • Cubs Starting Pitcher: Jameson Taillon (4-3, 2.90 ERA)
  • Mets Starting Pitcher: Tylor Megill (2-4, 4.81 ERA)
  • Records: Cubs (37-40), Mets (36-39)

Phillies vs. Diamondbacks Picks

Matchup Info & How to Watch

  • When: 4:05 PM ET
  • Where: Citizens Bank Parkin Philadelphia, Pennsylvania
  • TV Channel: NBCS-PH
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Phillies 5, Diamondbacks 3
  • Moneyline Pick: Phillies (-278) over the Diamondbacks (+220)
  • Total Pick: Under (9)

Head to BetMGM to bet on Phillies vs. Diamondbacks and more MLB games!

Starters & Team Records

  • Phillies Starting Pitcher: Zack Wheeler (9-4, 2.73 ERA)
  • Diamondbacks Starting Pitcher: Tommy Henry (2-3, 7.04 ERA)
  • Records: Phillies (50-26), Diamondbacks (38-39)

Pirates vs. Rays Picks

Matchup Info & How to Watch

  • When: 4:05 PM ET
  • Where: PNC Parkin Pittsburgh, Pennsylvania
  • TV Channel: BSSUN
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Pirates 5, Rays 4
  • Moneyline Pick: Pirates (-105) over the Rays (-115)
  • Total Pick: Over (8.5)

Head to BetMGM to bet on Pirates vs. Rays and more MLB games!

Starters & Team Records

  • Pirates Starting Pitcher: Jared Jones (5-6, 3.66 ERA)
  • Rays Starting Pitcher: Zach Eflin (3-5, 4.20 ERA)
  • Records: Pirates (37-39), Rays (37-40)

Rangers vs. Royals Picks

Matchup Info & How to Watch

  • When: 4:05 PM ET
  • Where: Globe Life Fieldin Arlington, Texas
  • TV Channel: MLB Network
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Rangers 5, Royals 4
  • Moneyline Pick: Rangers (-145) over the Royals (+120)
  • Total Pick: Under (8)

Head to BetMGM to bet on Rangers vs. Royals and more MLB games!

Starters & Team Records

  • Rangers Starting Pitcher: Jon Gray (3-3, 3.03 ERA)
  • Royals Starting Pitcher: Michael Wacha (4-6, 4.07 ERA)
  • Records: Rangers (36-40), Royals (42-36)

Athletics vs. Twins Picks

Matchup Info & How to Watch

  • When: 4:07 PM ET
  • Where: Oakland-Alameda County Coliseumin Oakland, California
  • TV Channel: NBCS-CA
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Twins 5, Athletics 4
  • Moneyline Pick: Twins (-185) over the Athletics (+150)
  • Total Pick: Over (8)

Head to BetMGM to bet on Athletics vs. Twins and more MLB games!

Starters & Team Records

  • Athletics Starting Pitcher: JP Sears (4-7, 5.04 ERA)
  • Twins Starting Pitcher: Bailey Ober (7-4, 4.50 ERA)
  • Records: Athletics (29-50), Twins (42-35)

Guardians vs. Blue Jays Picks

Matchup Info & How to Watch

  • When: 4:10 PM ET
  • Where: Progressive Fieldin Cleveland, Ohio
  • TV Channel: SNET
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Guardians 4, Blue Jays 3
  • Moneyline Pick: Guardians (-145) over the Blue Jays (+120)
  • Total Pick: Under (9)

Head to BetMGM to bet on Guardians vs. Blue Jays and more MLB games!

Starters & Team Records

  • Guardians Starting Pitcher: Ben Lively (7-3, 3.03 ERA)
  • Blue Jays Starting Pitcher: José Berríos (6-6, 3.43 ERA)
  • Records: Guardians (48-26), Blue Jays (35-41)

Reds vs. Red Sox Picks

Matchup Info & How to Watch

  • When: 4:10 PM ET
  • Where: Great American Ball Parkin Cincinnati, Ohio
  • TV Channel: BSOH
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Reds 5, Red Sox 4
  • Moneyline Pick: Reds (100) over the Red Sox (-120)
  • Total Pick: Under (9.5)

Head to BetMGM to bet on Reds vs. Red Sox and more MLB games!

Starters & Team Records

  • Reds Starting Pitcher: TBD
  • Red Sox Starting Pitcher: TBD
  • Records: Reds (36-39), Red Sox (40-36)

Astros vs. Orioles Picks

Matchup Info & How to Watch

  • When: 4:10 PM ET
  • Where: Minute Maid Parkin Houston, Texas
  • TV Channel: MASN
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Orioles 4, Astros 3
  • Moneyline Pick: Orioles (-155) over the Astros (+130)
  • Total Pick: Under (8)

Head to BetMGM to bet on Astros vs. Orioles and more MLB games!

Starters & Team Records

  • Astros Starting Pitcher: Ronel Blanco (8-2, 2.34 ERA)
  • Orioles Starting Pitcher: Corbin Burnes (8-3, 2.35 ERA)
  • Records: Astros (37-40), Orioles (49-27)

Marlins vs. Mariners Picks

Matchup Info & How to Watch

  • When: 4:10 PM ET
  • Where: LoanDepot parkin Miami, Florida
  • TV Channel: ROOT Sports NW
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Mariners 7, Marlins 6
  • Moneyline Pick: Mariners (-175) over the Marlins (+145)
  • Total Pick: Over (7.5)

Head to BetMGM to bet on Marlins vs. Mariners and more MLB games!

Starters & Team Records

  • Marlins Starting Pitcher: Shaun Anderson (0-2, 14.54 ERA)
  • Mariners Starting Pitcher: Logan Gilbert (5-4, 2.71 ERA)
  • Records: Marlins (26-50), Mariners (45-34)

Padres vs. Brewers Picks

Matchup Info & How to Watch

  • When: 7:15 PM ET
  • Where: PETCO Parkin San Diego, California
  • TV Channel: FOX
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Padres 6, Brewers 5
  • Moneyline Pick: Padres (100) over the Brewers (-120)
  • Total Pick: Over (8.5)

Head to BetMGM to bet on Padres vs. Brewers and more MLB games!

Starters & Team Records

  • Padres Starting Pitcher: Randy Vasquez (1-4, 5.70 ERA)
  • Brewers Starting Pitcher: Carlos Rodriguez (0-2, 6.48 ERA)
  • Records: Padres (40-40), Brewers (44-32)

Yankees vs. Braves Picks

Matchup Info & How to Watch

  • When: 7:15 PM ET
  • Where: Yankee Stadiumin The Bronx, New York
  • TV Channel: FOX
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Yankees 4, Braves 3
  • Moneyline Pick: Yankees (-125) over the Braves (+105)
  • Total Pick: Under (9)

Head to BetMGM to bet on Yankees vs. Braves and more MLB games!

Starters & Team Records

  • Yankees Starting Pitcher: Marcus Stroman (6-3, 3.19 ERA)
  • Braves Starting Pitcher: Charlie Morton (4-3, 3.91 ERA)
  • Records: Yankees (51-27), Braves (42-31)

Rockies vs. Nationals Picks

Matchup Info & How to Watch

  • When: 9:10 PM ET
  • Where: Coors Fieldin Denver, Colorado
  • TV Channel: MASN
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Nationals 5, Rockies 4
  • Moneyline Pick: Nationals (-115) over the Rockies (-105)
  • Total Pick: Under (10.5)

Head to BetMGM to bet on Rockies vs. Nationals and more MLB games!

Starters & Team Records

  • Rockies Starting Pitcher: Cal Quantrill (6-5, 3.43 ERA)
  • Nationals Starting Pitcher: Mitchell Parker (5-3, 3.06 ERA)
  • Records: Rockies (26-50), Nationals (37-38)

Dodgers vs. Angels Picks

Matchup Info & How to Watch

  • When: 10:10 PM ET
  • Where: Dodger Stadiumin Los Angeles, California
  • TV Channel: BSW
  • Live Stream: Fubo (regional restrictions may apply)

Click here for full predictions for this game!

Best Bets & Picks

  • Prediction: Dodgers 4, Angels 3
  • Moneyline Pick: Dodgers (-400) over the Angels (+300)
  • Total Pick: Under (8.5)

Head to BetMGM to bet on Dodgers vs. Angels and more MLB games!

Starters & Team Records

  • Dodgers Starting Pitcher: Tyler Glasnow (7-5, 3.00 ERA)
  • Angels Starting Pitcher: Zach Plesac (1-0, 4.50 ERA)
  • Records: Dodgers (47-31), Angels (30-45)

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