NFL Week 16 Odds and Lookahead Lines: Four Bets to Make This Weekend

Get a jump on NFL Week 16 odds & lookahead lines, along with four bets to place before lines begin to move for next week. Find updated NFL Week 16 odds below.

Week 16 NFL Odds & Lines

Lookahead NFL odds & Lines for Week 16

NFL Week 16 Betting Picks

Another full slate of games is on tap in Week 16, highlighted by a Christmas night matchup between the 49ers and Ravens. Some of the early lines are sure to shift after Week 15’s action, depending on the results.

Let’s take a look at which NFL bets to lock in early for Week 16.

Dallas Cowboys Moneyline (-110) vs. Miami Dolphins

The Dolphins are in a pretty difficult situation, with injuries starting to pile up. Losing center Connor Williams may not be a headline-grabbing development, but with other absences on the offensive line, the offense could certainly suffer without him.

With Williams and Jaelan Phillips done for the year plus Tyreek Hill less than 100 percent if he plays at all against the Jets, Miami could be in for a slog these next few weeks. A close game against New York, which looks rejuvenated on both sides of the ball and can take advantage of those offensive injuries, would damage Miami’s outlook ahead of this battle against the Cowboys.

Even a loss for Dallas in Buffalo wouldn’t be too damaging for the Cowboys’ outlook, considering how tough it is to win in that environment. Cowboys moneyline (-110) is in a great spot to lock in right now.

Jacksonville Jaguars (-2.5) vs. Tampa Bay Buccaneers

The Buccaneers don’t have much of a home-field advantage – they’re 3-3 at home this season and didn’t show a major advantage during the Tom Brady era – and that’s one reason to like the Jaguars in this matchup as long as the line is under a field goal.

Trevor Lawrence seemed to settle into playing on his injured ankle as Jacksonville’s game against the Browns went on, albeit a bit too late, and that progress should continue this week. By Week 16, Lawrence’s ankle could be in much better shape. A matchup with the Ravens in Week 15 is daunting, but Baltimore’s defense looked vulnerable against the Rams and could be gashed by Travis Etienne if the Jaguars play their cards correctly.

The Buccaneers, meanwhile, face a tough road as they go into Lambeau Field and could be brought back to Earth. We could see this line settle at 3-4 points in favor of the Jaguars.

Green Bay Packers (-4.5) vs. Carolina

This line shows a lack of faith in Jordan Love and the Packers after a loss to the Giants, but it’s too soon to overreact.

The offense pulled it together and impressed down the stretch even without Christian Watson and Aaron Jones. The defense was a major disappointment, but a unit that held Patrick Mahomes in check two weeks ago should have no problem wrangling in a Panthers offense that has shown zero signs of progress. Whether at home or on the road, Carolina has shown no indication that Bryce Young is on the verge of a breakout with his dismal supporting cast, and one more loss won’t help their outlook.

If the Packers can handle business at home against the Buccaneers, this line should settle beyond 4.5 points, making Green Bay an attractive pick right now.

Cincinnati Bengals Moneyline (-105) vs. Pittsburgh Steelers

This line will almost certainly move very soon, with or without positive news about Kenny Pickett in the fold for the Steelers. Pittsburgh has played like a bottom-tier team over the last three weeks, and surrendering 30 unanswered points to a Colts team missing large parts of its offense might be a greater concern than a loss to the Patriots. With Jake Browning appearing much improved from his first start against the Steelers, the Bengals should go into Pittsburgh as favorites regardless of the starting quarterback for Mike Tomlin’s squad.

Injuries could have an impact – Ja’Marr Chase’s health is critical – but it’s tough to justify any faith in a Steelers team that has melted down on both sides of the ball, particularly with the way the run defense got shredded in Indianapolis.

Dan is a lifelong sports fan and graduate of Boston University. He’s covered several sports on Instagram since he was 12 and now writes about everything from betting trends to breaking news for Lineups.

Hot NFL Stories