San Francisco 49ers vs. New York Giants Matchup Preview (9/27/20): Betting Odds, Depth Charts, Live Stream (Watch Online)

Both the Giants and 49ers were hit hard by the injury bug in Week 2. The 49ers played here last week against the Jets and had major issues with the turf and it continues to be an issue this week. San Francisco might be without Jimmy Garoppolo this week and they will be missing Raheem Mostert and Tevin Coleman. The Giants just signed Devonta Freeman as Saquon Barkley received the news that he will be out for the year. As both teams head into this week, there will be a lot of names that need to pick it up. The 49ers dealing with Nick Bosa being out for the year will hurt the defense. There is certainly a chance for the Giants to snag a win as they have been close in prior weeks but have fallen late. With the 49ers hindered on both sides of the ball, this could be a very ugly game.  For odds movement and full matchup history, visit the San Francisco 49ers at New York Giants Matchup Page.

TV Schedule

Date: Sunday, September 27th, 2020
Time: 1:00 PM ET
Location: MetLife Stadium, East Rutherford, NJ
TV Coverage: FOX

49ers vs. Giants Live Stream

Where can you watch 49ers vs. Giants online? You can stream this game and many other NFL games live online with Hulu. Hulu has a 7 Day free trial and is cheaper than cable options at $5.99/month. Watch 49ers Vs. Giants Free Online Now.

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Injuries:

San Francisco 49ers: Raheem Mostert (D), Tevin Coleman (O), Jimmy Garoppolo (Q), George Kittle (Q), Dee Ford (D), Jason Verrett (D)
New York Giants: Carter Coughlin (Q), Adrian Colbert (Q), Sterling Shepard (Q)

San Francisco 49ers Analysis

San Francisco 49ersSan Francisco continues to lose player after player as this is not the side they expected to have this week on either side of the ball. Defensively Jason Verrett is listed as doubtful and the same goes for Dee Ford. This is in addition to Nick Bosa being ruled out for the year and Richard Sherman is on IR. The 49ers have been lucky facing the Jets offense last week and now get lucky again facing the Giants without Saquon Barkley and Sterling Shepard. The 49ers rank 14th against the pass and 8th against the run so far this season, per Football Outsider’s DVOA. This might be a slugfest game in an ugly way given the Giants backfield isn’t field with names who can take advantage of a weakened front line. San Francisco has issues of their own at running back but with a healthy and better offensive line, they have the ability to handle the absences this week. Jeff Wilson and Jerick McKinnon will be the main backs and likely split the workload. Kyle Shanhan is a run game guru so I don’t expect either to miss a beat.

It sounds more and more like Jimmy Garoppolo and George Kittle are going to sit out this week. That means Nick Mullens and Jordan Reed will step into those roles. Mullens is a qualified backup and back when he filled in for the season there were teams calling about his services. The Giants defense hasn’t been bad this year and I think people are undervaluing them a bit. With a weakened receiving core who has done very little so far this season, Mullens will have his hands full trying to get guys who can move the ball.

San Francisco 49ers Depth Chart

QB: Jimmy Garoppolo
RB1: Jerick McKinnon
RB2: Jeff Wilson
WR1: Dante Pettis
WR2: Kendrick Bourne
WR3: Brandon Aiyuk
TE: George Kittle

New York Giants Analysis

New York GiantsThe brutal 2020 stretch of injuries hit the Giants hard in Week 2, losing Saquon Barkley for the year and Sterling Shepard over the next few weeks. They did just sign Devonta Freeman, but he will not be active this week. Instead it will be Dion Lewis and Wayne Gallman. Now Barkley had to face Chicago and Pittsburgh but the offensive line has looked extremely bad to start the year to the point where if Barkley can’t run behind them, how can we expect Lewis, Gallman, or Freeman to have any sort of success? We will see if they are able to step up against a 49ers defensive line that is missing two key pieces. Stopping the run was not hard to do last season for the Giants, they just saw a ton of volume due to the game scripts to make it look worse than what it was. They rank inside the top ten in DVOA against the run this year, and that should be no surprise after ranking 7th last season.

With Shepard out, we can expect Golden Tate and Darius Slayton to get a ton of looks. Slayton has that big play upside where Tate is going to be a safety blanket for Daniel Jones. Especially if the offensive line continues to struggle. Evan Engram has been quiet through two games, but has also faced two tougher opponents. The target will continue to be there and a breakout game could occur soon due to the fact they don’t have another body in the passing game mix to take targets away like Shepard. While the 49ers are still ranked as a top pass defense, missing two top corners and now key pass rushers, this is an easier matchup for Jones to take advantage compared to if the 49ers were full strength.

New York Giants Depth Chart

QB: Daniel Jones
RB1: Dion Lewis
RB2: Wayne Gallman
WR1: Darius Slayton
WR2: Golden Tate
WR3: Damion Ratley
TE: Evan Engram

Betting Corner: 49ers -4.5

Spread: SF -4.5
Moneyline: SF -200 / NYG +170
Over/Under: 40.5

This New York Giants defense is better than you think and with the injuries to the 49ers, this is a tricky game despite being 4.5 point favorites. Each team is 1-1 and public money is on the 49ers and also on the other. I am against both. With playmakers missing from both sides and a bad field, this just seems like a sloppy close scoring game that comes down to a field goal. Historical trends don’t mean much for me here with this game, and with the 49ers also being favorites this seems to indicate Jimmy Garoppolo is playing. However, Nick Mullens isn’t a bad name. I am curious to see if this line moves at all but the Giants covering is worthwhile as they have been competitive in their last two games against tougher opponents.

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Daily Fantasy Picks

darius slaytonI am not too fond of this game for fantasy in comparison to most of the others. The 49ers are dealing with injuries all over the place. Jerick McKinnon is an interesting fill-in name for Raheem Mostert, but will he get that full workload? Chances are he will not. The Giants defense is also better than people expect and the floors are lower than what you think. I do like McKinnon as a value but he isn’t a must play. The wide receivers are not much of a threat here for the 49ers and George Kittle is likely out this week.

With Sterling Shepard out, this does create some more stable targets for Darius Slayton, Golden Tate, and Evan Engram. I like these names in tournaments, but especially Slayton given his upside. Tate will be relied upon as well and the 49ers are dealing with injuries to the secondary with Jason Verett questionable and Richard Sherman on IR.

  
Jason Guilbault has been writing and podcasting in the fantasy sports world for over five years. You can find his work at Daily Fantasy Cafe. He is an avid Tottenham fan, and follows the Boston sports teams. When he isn’t diving into stats, he is enjoying the outdoors or down at the local brewery.

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