Best Anytime Touchdown Bets for Thursday Night Football At Bet365 Sportsbook

The NFL Week 15 schedule opens with an NFC West clash between the Los Angeles Rams and San Francisco 49ers. The Niners are favored by a field goal with both teams coming off big wins. Kickoff is scheduled for 8:15 p.m. ET at Levi’s Stadium, with Amazon Prime on the broadcast. 

Below, we highlight our best bets for anytime touchdown props at bet365 Sportsbook in this Thursday Night Football matchup. As a leader in offering boosted bets and same-game parlays, bet365 will increase the odds for certain NFL players leading up to these games, so check the sportsbook to see if prices have changed. 

Kyren Williams Week 15 Anytime Touchdown (LAR @ SF)

• Williams has been incredible at the goal line since he took over the lead back role for the Rams. He tied the franchise record with a touchdown in nine straight games before going scoreless in four straight games this season, but he’s started a new streak with four touchdowns over his last three games. Williams has scored thrice in two meetings with the 49ers, and that defense has been significantly diminished by injuries with Nick Bosa (oblique) and Dre Greenlaw (Achilles) again questionable for this contest. The Niners are allowing the third-most rushing touchdowns per game (1.5) and rank 31st in red zone defense, allowing opponents to score touchdowns on 72.1% of their possessions inside the 20-yard line. Rookie Blake Corum has taken a few snaps away from Williams, but all red zone work should still belong to the more experienced back. 

Puka Nacua Week 15 Anytime Touchdown (LAR @ SF)

• It appears Nacua has surpassed Cooper Kupp as the top target in this Rams offense, and he’s quickly becoming one of the most reliable receivers in the game. The 6-foot-2, 210-pound BYU product leads the NFL in target rate (37.5%) and yards per route run (3.54) with 111.2 receiving yards per game over his last five outings. Nacua has drawn nine red zone targets in that span and caught three touchdown passes. This week, he’ll line up against Charvarius Ward, who has allowed a 119.8 passer rating and given up four touchdowns in his coverage. 

Deebo Samuel Week 15 Anytime Touchdown (SF vs. LAR)

• The Niners continue to lose running backs, with Isaac Guerendo (foot) questionable to suit up on a short week. Patrick Taylor (-150 anytime touchdown odds at bet365) would assume lead back duties if Guerendo can’t play or winds up tapping out with the injury. In either case, the Niners would likely involve Samuel more often as another option out of the backfield. Samuel has been a bit of a “squeaky wheel” in complaining about his usage lately, as he’s coming off four straight games with under 25 total yards. His individual matchups were much tougher in those outings, and now he’ll face a Rams secondary that has allowed the second-most yards per pass (8.0) and a defense that has yielded 408.8 total yards per game over its last four contests.  

Jauan Jennings Week 15 Anytime Touchdown (SF vs. LAR)

• While Deebo has a chance to score on the ground or on short passes, Jennings has emerged as the top downfield option for Brock Purdy with Brandon Aiyuk (ACL) out for the year. Jennings has drawn at least one red zone target in nine of his 11 appearances this season and owns a 25% target share inside the opponents’ 20-yard line. The Niners weren’t forced to pass much in the second half of a blowout win last week, yet Jennings still finished with seven receptions for 90 yards and two touchdowns. He caught 11 of 12 targets for 175 yards and three touchdowns in a Week 3 matchup at the Rams, so the opposing defense might focus on his routes, but he’s clearly capable of getting open against this below-average secondary.