College Football Week 4 Underdog Picks, Odds, & Bets: Pac 12 Upsets in the Works?

Conference play is now beginning to heat up in college football and upsets could be in the works this week. Get the best College Football Week 4 underdog betting picks and odds.

Week 4 College Football Underdog Picks & Bets

It’s week 4 in college football, which means the schedule is finally dominated by conference play. For some teams, this weekend represents their first real test of the season. Who are some underdogs worth betting on this Saturday?

Arizona (+3) @ California

Jedd Fisch is quickly reviving Arizona, turning a 1-11 first season into a 2-1 start this year. The Wildcats have wins over San Diego State and FCS powerhouse North Dakota State, with a loss to Mississippi State sandwiched in the middle.

California has also looked better after a 5-7 season, including a near-miss against Notre Dame last week. The offense isn’t too inspiring, so the Wildcats might not have to worry about being torched through the air like they were against Mississippi State. Beating a solid Cal defense will be the challenge in this one, and it represents one of the early tests of an Arizona offense that has looked solid to this point.

Receiver Jacob Cowing could be a game-changer for Arizona. Cowing has 245 yards through three games and has scored at least one touchdown in each. QB Jayden de Laura already has a great connection with the UTEP transfer. If de Laura can limit turnovers, which were a big problem against Mississippi State, this passing game might have enough in the tank for an outright Arizona win.

Baylor (+2.5) @ Iowa State

This is a matchup of two teams that have been dominant against lesser competition but didn’t play their best in competitive matchups. Baylor suffered a 2OT loss to BYU two weeks ago, while Iowa State barely scraped by Iowa the same weekend.

As these two enter Big 12 play, don’t forget this was a Bears team that entered the season ranked 10th in the nation. Baylor still has many of the pieces that formed a dominant defense in 2021. The Bears shut down BYU’s running game two weeks ago and forced the Cougars to fight for any points they could get after the third quarter.

Iowa State has some new pieces on its offense after losing Brock Purdy and Breece Hall, and Baylor might be able to have the same effect on the unproven Cyclones offense that Iowa did two weeks ago.

Rutgers (+7.5) vs. Iowa

Is there any reason to believe Iowa has enough in the tank offensively to win by more than a touchdown on the road? The Hawkeyes are coming off a 27-0 win over a Nevada team that lost to Incarnate Word the previous week. Aside from that game, Iowa has a 10-7 loss to Iowa State and a 7-3 win over South Dakota State on its record.

Rutgers isn’t the most fundamentally sound team, but the Scarlet Knights have scrapped their way to a 3-0 start. The offense will struggle against Iowa. It’s not good enough to go in and wreck a defense like the Hawkeyes have, let alone most other power-five defenses. Rutgers does have enough of a defense to send Iowa’s offense back to its struggles of the first two weeks.

This game may come down to turnovers, and Rutgers only has two turnovers through three games. Iowa has five. Rutgers +7.5 is still much more likely than an outright win.

Washington State (+7) vs. Oregon

Sometimes you get the best version of Bo Nix, and sometimes you get the worst version. After an awful Week 1, the best version of Nix has shown up for Oregon in the Ducks’ last two games. Is he due for disappointment?

As Oregon goes on the road for the first time since its 49-3 loss to Georgia, it faces a Washington State team that’s thriving under Jake Dickert. The undefeated Cougars knocked off Wisconsin on the road in Week 2 and blew out Colorado State last Saturday.

Transfer QB Cameron Ward has looked strong with 715 yards, 8 touchdowns, and 3 interceptions through three games. The defense has looked even stronger, holding Wisconsin’s Braelon Allen under 100 rushing yards in the Week 2 upset. If the defense can get Nix rattled on the road, Washington State has a real chance to cover +7 or win outright.

Dan is a lifelong sports fan and graduate of Boston University. He’s covered several sports on Instagram since he was 12 and now writes about everything from betting trends to breaking news for Lineups.

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