Los Angeles Rams vs Arizona Cardinals NFL Player Props & Picks (9/25/22)

Get NFL player props and picks for the Los Angeles Rams vs. Arizona Cardinals matchup on (9/25/22)

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Los Angeles Rams vs. Arizona Cardinals Player Prop Picks

In week 3 of the 2022 NFL season, the Los Angeles Rams (1-1) travel to Phoenix to take on the Arizona Cardinals (1-1) on Sep. 25 at State Farm Stadium. The defending Super Bowl champions are road favorites with a -3.5 spread in a game that could see plenty of offense despite the modest over/under of 48.5 points. Let’s take a look at some player prop bets I like in this NFC West divisional matchup.

Kyler Murray over 26.5 rushing yards (-120 on DraftKings)¬

For his career, Murray averages 38.4 rushing yards per game. He averaged 30.2 rushing yards per game last season and is averaging 28.5 so far this season. As of this writing on Friday, RB James Conner is questionable for this game.

#AZCardinals RB James Conner is a game-time decision, per Kliff Kingsbury.

— Tyler Drake (@Tdrake4sports) September 23, 2022

Murray won’t necessarily see additional rushing work if Conner doesn’t play – those carries would likely go to Darrell Williams and/or Eno Benjamin. But Conner’s absence could signal more red zone rushing attempts for Murray, which boosts his chances to pick up a few extra carries in this game and hit the rushing yards over. For a similar reason, I also like Murray’s odds for an anytime touchdown at +170 on DraftKings.

Darrell Henderson Jr. over 38.5 rushing yards (-120 on DraftKings)

Henderson has rushed for 47 yards in each of his first two games and is averaging 4.1 yards per carry so far this season, just under his career average of 4.4. In three career games against the Cardinals, he has averaged 51.7 yards per game and 7.38 yards per carry. Henderson has outsnapped Cam Akers in both games so far this season, and even though coach Sean McVay got Akers more involved in the game plan in week 2, Henderson still played more than 50% of the snaps and got 10 carries. I expect Akers to eventually take over the majority of the backfield snaps and touches as he continues to get stronger in his recovery from a torn achilles, but Henderson isn’t going away anytime soon. Henderson has been the more effective and efficient runner through two games, and in a game the Rams are expected to lead, he should see enough volume to hit the over on 38.5 rushing yards.

I also kind of like Henderson’s +140 odds for over 2.5 receptions in the game. He had five catches in week one and has averaged 2.4 receptions per game over the last two seasons.

Cooper Kupp over 97.5 receiving yards (-115 on DraftKings)

When in doubt, take the over on Cooper Kupp’s receiving yards. Kupp hit the over on his receiving yards prop line in 15 of his 17 games last season, and in his first two games so far this season. He averaged 114.5 receiving yards per game in his historic 2021 season and he is averaging 118 yards through two games this season. One mitigating factor is that Kupp’s worst game of the 2021 season came against these Cardinals (13 targets, 5 catches, 64 yards, no TDs in week 4). But in the other game against the Cardinals, in week 13 on the road, he went for 13 catches, 123 yards and one touchdown. Normally I would be scared off by a massive line of 97.5 receiving yards, but it doesn’t scare me to bet on Kupp.

And if you want a free buck, bet $200 on Kupp’s DraftKings special of 1+ catch at -20000.