NFL Week 4 Underdog Betting Picks, Odds, and Bets: Rams Road Dogs On Monday Night Football

The wildness of the NFL Season continues and Week 4 has a few underdog betting picks to keep an eye on. Baltimore looks to keep their streak going, while the Rams are road dogs in an MNF battle.

Week 4 NFL Underdog Betting Picks & Bets

The NFL season continues to bring surprises, and Week 3 had a few of them. The Colts knocked off the 2-0 Chiefs, and the Jaguars beat the Chargers by four touchdowns in a statement win as the AFC South struck back against doubters. Which underdogs might be the best bets ahead of Week 4?

Los Angeles Rams (+110) vs. San Francisco 49ers

I believe the 49ers are a better team than what we saw on Sunday night, but the offense is clearly missing something. Whether it’s the loss of Mike McDaniel, running back injuries, or quarterback turnover, there are a few issues to work out. The loss of Trent Williams for a few weeks won’t help at all.

The fact that this game is at Levi’s Stadium isn’t enough for me to believe the 49ers will win. Yes, San Francisco played the Rams closely all last season, winning twice in the regular season. Turnovers by Matthew Stafford are a concern. The reigning champions aren’t perfect – but they’re improving.

LA’s defense looks like it’s settled in, holding down the Cardinals’ offense on the road this past weekend. With Williams out, the Rams’ defensive front should be able to take advantage of a weak ‘Niners offensive line and harass Jimmy Garoppolo.

If Stafford can avoid costly turnovers, the Rams probably won’t need too much out of their offense to get this win. At +110 on the moneyline, Sean McVay’s group is a great value.

Houston Texans (+4.5) vs. Los Angeles Chargers

The Chargers are totally unpredictable, and there’s no better proof of that than a stunning loss to these Texans last December. There was no reason for it to happen, considering the talent gap, but it cost LA a playoff spot in the end.

This time around, the Chargers’ roster is gutted by injuries. Keenan Allen is set to return this week, but J.C. Jackson and Corey Linsley might not play while Rashawn Slater, Joey Bosa, and Jalen Guyton are all out. Justin Herbert is also playing through a painful rib injury.

I would say the Chargers win largely because the Texans’ run defense has been abysmal this season, but with this game in Houston, it wouldn’t surprise me at all if Davis Mills recaptures a bit of what he found late last season and forces this one down to the wire.

Baltimore Ravens (+145) vs. Buffalo Bills

The Ravens can win any game as long as Lamar Jackson is their quarterback. You could say the same about the Bills and Josh Allen, but this is a Buffalo team that has been hit hard by injuries lately. The secondary has been depleted to the point that they went out and signed Xavier Rhodes, and the loss of Micah Hyde – along with Jordan Poyer’s uncertain status for this game – leaves a hole at the safety position.

Jackson has been playing well enough to dominate healthy secondaries, let alone a beaten up secondary. Mark Andrews has been dominant in the red zone, and Jackson looks very comfortable with both Rashod Bateman and Devin Duvernay.

I still have questions about the Ravens’ defense, which was torched by the Dolphins in Week 2 and had some highs and lows against the Patriots this past weekend. This could absolutely be a shootout. If that’s what it is, this Ravens offense can compete with any team right now – even the Bills. At home, Baltimore moneyline (+145) looks like the better value.

Dan is a lifelong sports fan and graduate of Boston University. He’s covered several sports on Instagram since he was 12 and now writes about everything from betting trends to breaking news for Lineups.

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