NFL Week 6 Odds and Lookahead Lines: Four Bets to Make This Weekend

Get a jump on NFL Week 6 odds & lookahead lines, along with four bets to place before lines begin to move for next week. Find updated NFL Week 6 odds below.

Week 6 NFL Odds & Lines

Lookahead NFL odds & Lines for Week 6

Early NFL Week 56Bets To Place

Week 5 of the NFL season is just getting underway, but it’s not too early to start thinking about Week 6 bets. Let’s take a look at which bets you might want to lock in before this week’s action moves some of the lines.

Cincinnati Bengals (Pick ‘Em) vs. New Orleans Saints

Jameis Winston could be back for this game, which I see as bad news for the Saints. A defense that does a nice job of forcing turnovers going up against a turnover-prone quarterback isn’t ideal for New Orleans. That’s one reason we could see money pour in on the Bengals as this game gets closer.

If the Saints lose to the Seahawks at home this weekend or barely escape with the win, you could easily see this line shift toward Cincinnati. After seeing what Seattle’s offense was able to do to the Lions, it’s not far-fetched that the Seahawks give this banged up New Orleans team a serious challenge.

A disappointing showing by the Saints would prove home-field advantage isn’t enough of a factor to overcome the reality of the Bengals having the better roster. The Bengals also have a chance for a statement win in Baltimore this weekend. If you’re on Cincinnati in this game, it’s too risky to wait.

Jacksonville Jaguars Moneyline (+115) vs. Indianapolis Colts

I tried to believe in the Colts after their win over the Chiefs, but the loss to Tennessee sent them right back to where they started.

After going down 24-17 midway through the third quarter, the Colts had numerous chances to tie the game (or score any points at all) and just didn’t have the offense to do it. Matt Ryan posted empty stats, and Jonathan Taylor was totally shut down by the Titans’ defense before exiting with an injury. We don’t know what Taylor’s status will be against the Jaguars, who already did a nice job against him this season.

Doug Pederson’s team already has a dominant win over the Colts this year. With Jacksonville poised to cruise to a win over the Texans this weekend, I wouldn’t be surprised if the Jaguars became favorites next week.

Seattle Seahawks Moneyline (+115) vs. Arizona Cardinals

The Seahawks are 2.5-point home underdogs against the Cardinals at this point, sitting at +115 on the moneyline. I could see that changing after this weekend.

The Cardinals haven’t played inspiring football this season, getting by the Panthers this past weekend largely due to Carolina’s persistent offensive troubles. Arizona is due for a home loss against the undefeated Eagles on Sunday, while Seattle has a chance to make some noise against a depleted Saints team.

If the Seahawks move to 3-2 and begin to look like their relative success is sustainable, the Cardinals might lose their status as favorites in one of the most difficult environments for any road team in the NFL. It’s worth noting this will be Arizona’s final game before DeAndre Hopkins’ return.

New England Patriots (+3.5) vs. Cleveland Browns

The Patriots flashed some impressive defensive ability against the Packers in Week 4. With Mac Jones expected back for Week 6, if not sooner, could the Patriots start rattling off some wins just like they did around this time last year?

The Browns are 2-2 through four games and have been perfectly average to this point with close wins over the Panthers and Steelers – two teams with poor offenses – and close losses to a pair of downtrodden teams in the Jets and Falcons. If Cleveland falters against the Chargers at home, this line could move under a field goal.

The Patriots also have a winnable game this weekend as they get set to face the Lions at home. Regardless of who is under center for New England, Detroit’s defensive issues give Bill Belichick’s team an opportunity.

If you think the Patriots can go into Cleveland and at least keep it close, it’s better to get this line before it dips under a field goal.

Dan is a lifelong sports fan and graduate of Boston University. He’s covered several sports on Instagram since he was 12 and now writes about everything from betting trends to breaking news for Lineups.

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