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Last week in the NFL, we watched some very notable players like Saquon Barkley and Jimmy Garrapolo go down with serious injuries. Without preseason or the ability to use exhibition matchups to get used to game-play, the NFL players went straight into the regular season from training camp and some have suffered the consequence of getting injured. I will be analyzing key injuries to know for fantasy football owners and who might take their spot.
Atlanta Falcons vs. Chicago Bears
Julio Jones (questionable): Julio Jones is rumored to be a game-time decision for Sunday’s matchup versus the Chicago Bears. Julio has been underperforming his expectations so far for fantasy football this season. However, Calvin Ridley and Russell Gage have been outstanding in the passing game. If Julio is out for Sunday expect those two and Hayden Hurst to get more targets in the passing game.
Buffalo Bills vs. Los Angeles Rams
John Brown (questionable): John Brown has been dealing with a foot injury and has not been limited in practice. He did not practice on Thursday most likely to keep him off of his feet for Sunday. He has strong chances to play, but in case he does not, expect more targets heading to Stefon Diggs and Cole Beasley.
Zack Moss (out): Zack Moss has been officially ruled out for Sunday’s game with a toe injury. This is better news for fantasy owners of Devin Singletary, who has been quiet this season in fantasy football. Expect Singletary to get the majority of carries in the Bills’ backfield on Sunday.
Cam Akers (questionable): Cam Akers has not practiced much this week after a rib injury that took him out of last week’s game. Besides the injury, Akers has been disappointing to fantasy owners by underproducing in the backfield. He had a decent amount of touches that will transfer over to Malcolm Brown and Darell Henderson in week three.
Cleveland Browns vs. Washington Football Team
Steven Sims (questionable): Steven Sims Jr. has been dealing with a toe issue this week that has kept him limited in practice. He looks good to play on Sunday so he should be in the conversation of a low-production flex option for week three.
Minnesoa Vikings vs. Tennessee Titans
New England Patriots vs. Las Vegas Raiders
Julian Edelman (questionable): Julian Edelman has been dealing with an injury to his knee which has kept him limited in practice. His limited practice time is most likely a ploy to keep him healthy for Sunday’s game. He should play after coming off a monster 8 catch game for 179 yards last week.
N’Keal Harry (questionable): N’keal Harry has also been limited in practice with an ankle injury. Neither he nor Edelman seems to be in danger for being absent on Sunday, however, if either of them are limited in the game Damiere Byrd could be seeing for targets.
Henry Ruggs III (questionable): Henry Ruggs has been limited this week due to a knee injury, but he looks like he has a good chance to play Sunday. With the doubtful presence of Darren Waller, he should see a high increase in targets if he can play.
Josh Jacobs (questionable): Josh Jacobs has not practiced much this week due to a hip injury. He will most likely be a late or game-time decision for playing on Sunday. Owners of Jacobs should be aware of his status for Sunday and know that Jalen Richard will probably be the lead back.
Darren Waller (questionable): Darren Waller has not been practicing much this week and will be in the same boat as Jacobs for playing on Sunday. His absence will deliver more targets to Henry Ruggs III, if he plays, and possibly Bryan Edwards. Waller has been key for Derek Carr this season and has not given many targets to receivers worth starting in fantasy so I would work the waiver wire for a tight end in week three.
New York Giants vs. San Francisco 49ers
Saquon Barkley (out for season): Saquon Barkley tore his ACL last week against the Chicago Bears. Barkley was a highly anticipated fantasy player this season and his injury will affect many owners. Dion Lewis is in line to see more carries, but the team also signed veteran running back Devonta Freeman after Barkley’s ACL was confirmed to be torn. I would wait to see who will get most of the carries in week three before picking up any of these backs.
Sterling Shepard (IR): Sterling Shepard is on injured reserve with a toe injury and will be expected back in week six. Evan Engram, Darius Slayton, and Golden Tate should see more targets from Daniel Jones in week three and for the following weeks.
Jimmy Garoppolo (out): Jimmy Garoppolo is confirmed to be out for Sunday and Nick Mullens will start in place of him. It seemed like he had a chance of playing this week, so he should be good to start next week.
Raheem Mostert (doubtful): Raheem Mostert is out for week three against the Giants with a knee injury. Mostert’s fantasy performance has been very solid this season and his absence should be short term. Since Tevin Coleman will most likely not play on Sunday, Jerick McKinnon will lead the backfield for the 49ers.
Tevin Coleman (doubtful): Tevin Coleman is not expected to play on Sunday for a knee injury. Coleman’s injury seems to be the worst of the 49er running back committee and has a chance of being placed on injured reserve.
George Kittle (out): George Kittle is out for Sunday’s game. Without Garoppolo for Sunday either, the San Francisco wide receivers may struggle. Kendrick Bourne and Brandon Aiyuk are most likely not worth the flex play on Sunday with the large amount of adversity that the 49ers are facing.
Philadelphia Eagles vs. Cincinnati Bengals
Jalen Reagor (doubtful): Jalen Reagor is set to have surgery to repair his thumb which will cause him to be out for a few weeks. Without him and Alshon Jeffery, look to see Zach Ertz and Desean Jackson receiving most of the action.
Alshon Jeffery (questionable): After being limited in practice this week, Alshon Jeffery has been ruled out for Sunday. His injuries have always been a concern and fantasy owners should look to move on from him.
Pittsburgh Steelers vs. Houston Texans
Juju Smith-Schuster (questionable): Juju Smith-Schuster did not practice Thursday or Wednesday this week, but it does not seem like his participation Sunday is in immediate danger. Check his status before the game to see if he is playing. Diontae Johnson and Eric Ebron would see more targets without him.
Brandin Cooks (questionable): Brandin Cooks has been dealing with a quadriceps injury since training camp and it has not stopped him from playing. Expect to see him out there on Sunday.
Duke Johnson (questionable): Duke Johnson‘s status is still in question for Sunday, but David Johnson should see the majority of the action regardless of his status.
Indianapolis Colts vs. New York Jets
Parris Campbell (IR): Parris Campbell has been placed on injured reserve with a knee injury that sets him back to play week six at the earliest. His absence will give more attention to T.Y Hilton, Zach Pascal, and Mo Allie-Cox, who are all possible fantasy options.
Jack Doyle (questionable): Jack Doyle has been limited in practice after missing earlier in the week with a knee injury. He should be ready to go for Sunday but has battled targets at the tight end position with Mo Alli-Cox.
Los Angeles Chargers vs. Carolina Panthers
Tyrod Taylor (doubtful): Tyrod Taylor was involved in an alarming situation with a team doctor that may keep him out of games for a decent amount of time. Justin Herbert is worth the waiver wire pick up after playing very well against the Chiefs last week.
Christian McCaffrey (IR): Sadly, Christian McCaffrey suffered an ankle injury last week that has landed him on injured reserve. Mike Davis is set to be the lead back and a possible fantasy starter pending his performance this week.
Denver Broncos vs. Tampa Bay Buccaneers
Drew Lock (out): Drew Lock suffered a shoulder injury that is expected to keep him out for a significant amount of time. Jeff Driskel is the backup quarterback, but not worth the pickup.
Phillip Lindsay (doubtful): Phillip Lindsay has been missing practice due to a toe injury that may keep him out Sunday. Melvin Gordon should see a healthy amount of touches on Sunday if Lindsay does not play.
Courtland Sutton (out for the season): Courtland Sutton is out for the season after suffering a torn ACL and MCL injury. More targets will be in line for Noah Fant and Jerry Jeudy.
Jerry Jeudy (questionable): Jerry Jeudy has been doing better this week with a rib injury and should play Sunday. However, without Drew Lock, I am not high on starting Jeudy against the Buccaneers for week three.
Arizona Cardinals vs. Detroit Lions
Christian Kirk (questionable): Christian Kirk‘s availability to play Sunday does not seem likely with a groin injury. Without him, Larry Fitzgerald and Deandre Hopkins should see more targets. However, Hopkins usually receives most of the targets over any other receiver, but Larry should see more as the second option.
Seattle Seahawks vs. Dallas Cowboys
All good for fantasy football!
New Orleans Saints vs. Green Bay Packers
Michael Thomas (doubtful): Michael Thomas is trying to beat out his projected timeline for return, but it does not look good for Sunday. Look for him to try to return next week.
Baltimore Ravens vs. Kansas City Chiefs
Sammy Watkins (questionable): Sammy Watkins has been going through concussion protocol and has been having neck pain. However, with this game being Monday night, fantasy owners will have more time to see if he will be able to play.