NFL Week 6 PPR Rankings: Ja’Marr Chase Has Arrived as a Top Ten WR

Week 6 of the NFL season is here, and it’s hard to believe we’re already a month and a half into the season. Bye weeks have arrived, and the Saints, 49ers, Falcons, and Jets will not be taking the field this week. That means fantasy football stars like Alvin Kamara, Deebo Samuel, and Cordarelle Patterson won’t be available for your lineup this week – adjust accordingly. With some massive matchups on the horizon and plenty of fantasy potential on this week’s slate, let’s take a look at the top options at each position.

NFL Week 6 Quarterback Rankings


Josh Allen is positioned at the top of my rankings, and he should feast in a matchup against the pitiful Titans’ defense on Monday night. Kyler Murray isn’t far off in my projections as the current MVP favorite faces the Browns, who have surprisingly allowed the fifth-most fantasy points to quarterbacks this season. Patrick Mahomes is in line with those two quarterbacks in a matchup against Washington, who has allowed the second-most fantasy points to QBs. On the other side in that matchup, Taylor Heinecke is one of my favorite streamers this week against the Chiefs, who have arguably the worst defense in the NFL right now. Tom Brady should have an epic performance on Thursday against a mediocre Eagles’ defense after throwing five touchdowns last week. Justin Herbert and Lamar Jackson are both obvious top-ten options as they face off in what should be an exciting AFC showdown between the Chargers and Ravens. Dak Prescott has lower upside on the road against the Patriots but is a no-doubt starter, and the same goes for Matthew Stafford, who travels to face an underperforming Giants’ defense. Jalen Hurts may have to play a tough Tampa front seven, but he should be in your lineup. Aaron Rodgers is in the same boat as a must-start despite a tough matchup. Joe Burrow has played his way into starting consideration every week, especially against the Lions, while Kirk Cousins should get back on track this week. Sam Darnold, Ryan Tannehill, Baker Mayfield, and Trevor Lawrence are some of the lower-upside streamers in consideration.

NFL Week 6 Running Back Rankings


Derrick Henry leads the NFL with 640 rushing yards, and the next-closest player has over 100 fewer yards. However, Henry faces the Bills this week, who have allowed the fewest fantasy points to running backs. Henry is still my RB1 on the week, but his upside is significantly lower given the tough matchup. Antonio Gibson stands out as an excellent play against a struggling Chiefs’ defense that has allowed some huge performances to opposing RBs. Joe Mixon has a similarly excellent matchup and if we get better news to give me more confidence in his health I’ll be moving him up in the rankings. Darrell Henderson should get a ton of usage as the Rams are favored by 10.5 points on the road against an injured Giants team. Najee Harris has been one of the most heavily-utilized running backs in the NFL and should take advantage of a struggling Seahawks’ defense that has allowed the fourth-most fantasy points to RBs. Christian McCaffrey and Dalvin Cook will be two names to watch as the superstar running backs could be making a full return this week, but their health is still up in the air. The Panthers and Vikings play against one another this week, and if those star backs are unable to play, Chuba Hubbard and Alexander Mattison would be clear top-20 options. With several starting running backs injured, Damien Williams, Darrel Williams, and Devontae Booker are among the names now in consideration for your starting lineup.

NFL Week 6 Wide Receiver Rankings


Davante Adams is in his own tier at the wide receiver position, and he showed that again on Sunday when he finished with 11 catches for 206 yards and a touchdown. It’s hard to imagine him not being my WR1 in the rankings no matter the matchup. Tyreek Hill isn’t too far behind, though, and the Chiefs’ wide receiver has another excellent matchup against Washington’s struggling defense. That game should be a shootout, which will also allow Terry McLaurin to finish as a top-ten wide receiver on the other side. Justin Jefferson, Stefon Diggs, Cooper Kupp, and DeAndre Hopkins are some of the usual suspects in my top ten. Ja’Marr Chase has entered the top ten after another excellent performance and I look like a fool for fading him prior to draft season – I’ll happily take that L as the Bengals’ wideout is one of the best young talents in the NFL. The Buccaneers’ wideouts are all around the top-15 range and are must-start options, as are the Cowboys’ and Chargers’ wideouts. The Seahawks’ wideouts are typically in that conversation, but with Geno Smith at quarterback in place of the injured Russell Wilson, I have their projections deflated significantly. Robert Woods broke through last week, and I’m confident putting him back into starting consideration while Michael Pittman Jr., Devonta Smith, and Henry Ruggs are some of the young players breaking through this season.

NFL Week 6 Tight End Rankings


The tight end position is in constant flux in fantasy football. Still, the constants remain as Travis Kelce, Darren Waller, Mark Andrews, and T.J. Hockenson are reliable every week starts atop my rankings. Of course, George Kittle is also in that group while Kyle Pitts is working his way into that group; both are on bye this week. Zach Ertz will have a solid game, with Dallas Goedert likely missing Thursday’s game after landing on the COVID-19 reserve list. Dawson Knox and Dalton Schultz are two of the breakout players at tight end this season, and they are both back in my top ten this week. Noah Fant, Mike Gesicki, and Tyler Higbee have been pretty reliable, as well. Ricky Seals-Jones caught five passes for 41 yards last week in relief of Logan Thomas and is in starting consideration until Thomas returns. Hunter Henry continues to out-produce Jonnu Smith while David Njoku continues to outshine Austin Hooper – both Henry and Njoku are worthy of starts this week. Dan Arnold, Tyler Conklin, and Mo Alie-Cox are some of the deeper names to keep an eye on in Week 6.

I've been writing about sports for Lineups since the beginning of 2020 and on my own website since 2018. In May 2021, I graduated from the University of Michigan with a degree in sport management. I've been playing fantasy football for as long as I can remember and am now in far more leagues than any person should take part in. There are few things that give me as much joy and excitement as fantasy football, and I'm excited to share my input with you in your journey towards a championship.

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