NFL Odds Week 12

The current Week 12 betting odds for the 2022 NFL season feature everything from short home underdogs to heavy road favorites. Whether it be Giants vs Cowboys, Packers vs Eagles or another one of the marquee matchups on this slate — Week 12 has a little something for everyone. Above all, though, Week 12 offers an opportunity for prospective bettors across the country to have a personal stake in the odds of the long-anticipated NFL season. At Lineups, we’ve dedicated our direct access to sportsbooks, data science avenues, and dedicated analysts to provide you with the most up-to-date information and analysis on week-by-week NFL odds. In the tables below, you’ll find odds comparisons from different sportsbooks as well as the best NFL odds on whichever side you believe has the edge.

DraftKings
FanDuel
BetMGM
Caesars
Game
DraftKings Odds
FanDuel Odds
BetMGM Odds
Caesars Odds
Date/Time Teams ML Spread O/U ML Spread O/U ML Spread O/U ML Spread O/U
11/24, 5:30 pm GMT Buffalo Bills Bills
-410
-9.5 -110
o54.5 -110
-450
-9.5 -114
o54.5 -115
-450
-9.5 -110
o54.5 -110
-440
-9.5 -110
o55 -110
Detroit Lions Lions
+330
+9.5 -110
u54.5 -110
+350
+9.5 -106
u54.5 -105
+350
+9.5 -110
u54.5 -110
+335
+9.5 -110
u55 -110
11/24, 9:30 pm GMT New York Giants Giants
+350
+10 -115
o46 -110
+385
+10 -108
o45.5 -112
+360
+10 -110
o45.5 -110
+360
+10 -110
o45.5 -110
Dallas Cowboys Cowboys
-435
-10 -105
u46 -110
-500
-10 -112
u45.5 -108
-500
-10 -110
u45.5 -110
-480
-10 -110
u45.5 -110
11/25, 1:20 am GMT New England Patriots Patriots
+125
+2.5 +100
o42 -110
+128
+2.5 -108
o42.5 -105
+120
+2.5 -105
o42 -110
+122
+2.5 -105
o41.5 -110
Minnesota Vikings Vikings
-145
-2.5 -120
u42 -110
-152
-2.5 -112
u42.5 -115
-145
-2.5 -115
u42 -110
-145
-2.5 -115
u41.5 -110
11/27, 6:00 pm GMT Denver Broncos Broncos
-115
-1 -105
o37 -110
-122
-1 -118
o36.5 -106
-120
-1 -110
o36.5 -110
-110
-1 -110
o36.5 -110
Carolina Panthers Panthers
-105
+1 -115
u37 -110
+104
+1 -104
u36.5 -114
+100
+1 -110
u36.5 -110
-110
+1 -110
u36.5 -110
11/27, 6:00 pm GMT Tampa Bay Buccaneers Buccaneers
-180
-3.5 -105
o42 -110
-174
-3.5 -104
o42.5 -104
-175
-3.5 -105
o42 -110
-178
-3 -120
o42 -110
Cleveland Browns Browns
+155
+3.5 -115
u42 -110
+146
+3.5 -118
u42.5 -118
+145
+3.5 -115
u42 -110
+150
+3 +100
u42 -110
11/27, 6:00 pm GMT Baltimore Ravens Ravens
-170
-3 -120
o43 -110
-164
-3.5 -105
o43.5 -105
-165
-3 -115
o43.5 -110
-170
-3 -115
o43 -110
Jacksonville Jaguars Jaguars
+145
+3 +100
u43 -110
+138
+3.5 -115
u43.5 -115
+140
+3 -105
u43.5 -110
+143
+3 -105
u43 -110
11/27, 6:00 pm GMT Houston Texans Texans
+700
+15 -110
o47 -115
+570
+14 -105
o47.5 -105
+575
+14 -110
o47.5 -110
+600
+14 -110
o47 -110
Miami Dolphins Dolphins
-1050
-15 -110
u47 -105
-820
-14 -115
u47.5 -115
-900
-14 -110
u47.5 -110
-900
-14 -110
u47 -110
11/27, 6:00 pm GMT Chicago Bears Bears
+310
+8 -110
o36.5 -110
+315
+7.5 -105
o36.5 -110
+300
+7.5 -110
o36.5 -110
+300
+7.5 -110
o36.5 -110
New York Jets Jets
-380
-8 -110
u36.5 -110
-400
-7.5 -115
u36.5 -110
-375
-7.5 -110
u36.5 -110
-385
-7.5 -110
u36.5 -110
11/27, 6:00 pm GMT Cincinnati Bengals Bengals
-105
-1 +100
o42 -110
-108
-1 -104
o42.5 -110
-115
-1 -110
o42.5 -110
-105
-1 -110
o42.5 -110
Tennessee Titans Titans
-115
+1 -120
u42 -110
-108
+1 -118
u42.5 -110
-105
+1 -110
u42.5 -110
-115
+1 -110
u42.5 -110
11/27, 6:00 pm GMT Atlanta Falcons Falcons
+165
+3.5 -105
o40.5 -110
+160
+3.5 -110
o40.5 -112
+155
+3.5 -105
o40.5 -110
+158
+3.5 -110
o40 -110
Washington Commanders Commanders
-195
-3.5 -115
u40.5 -110
-190
-3.5 -110
u40.5 -108
-190
-3.5 -115
u40.5 -110
-190
-3.5 -110
u40 -110
11/27, 9:05 pm GMT Los Angeles Chargers Chargers
-150
-2.5 -120
o49 -110
-142
-2.5 -114
o48.5 -115
-145
-2.5 -115
o48.5 -110
-145
-2.5 -120
o49 -110
Arizona Cardinals Cardinals
+130
+2.5 +100
u49 -110
+120
+2.5 -106
u48.5 -105
+120
+2.5 -105
u48.5 -110
+122
+2.5 +100
u49 -110
11/27, 9:05 pm GMT Las Vegas Raiders Raiders
+170
+4 -110
o47.5 -110
+180
+4 -110
o47.5 -115
+155
+3.5 -105
o47.5 -110
+170
+4 -110
o48 -110
Seattle Seahawks Seahawks
-200
-4 -110
u47.5 -110
-215
-4 -110
u47.5 -105
-190
-3.5 -115
u47.5 -110
-205
-4 -110
u48 -110
11/27, 9:25 pm GMT Los Angeles Rams Rams
+800
+16 -110
o42 -110
+810
+16.5 -115
o41.5 -115
+775
+15.5 -110
o42 -110
+800
+15.5 -110
o42 -110
Kansas City Chiefs Chiefs
-1250
-16 -110
u42 -110
-1350
-16.5 -105
u41.5 -105
-1400
-15.5 -110
u42 -110
-1400
-15.5 -110
u42 -110
11/27, 9:25 pm GMT New Orleans Saints Saints
+330
+8.5 -110
o43.5 -110
+300
+8.5 -115
o43.5 -110
+333
+8.5 -105
o43.5 -110
+328
+8.5 -110
o43.5 -110
San Francisco 49ers 49ers
-410
-8.5 -110
u43.5 -110
-375
-8.5 -105
u43.5 -110
-450
-8.5 -115
u43.5 -110
-430
-8.5 -110
u43.5 -110
11/28, 1:20 am GMT Green Bay Packers Packers
+225
+6.5 -105
o46 -115
+235
+6.5 -110
o46.5 -105
+230
+6.5 -110
o46.5 -110
+228
+6.5 -110
o46 -110
Philadelphia Eagles Eagles
-265
-6.5 -115
u46 -105
-290
-6.5 -110
u46.5 -115
-300
-6.5 -110
u46.5 -110
-285
-6.5 -110
u46 -110
11/29, 1:15 am GMT Pittsburgh Steelers Steelers
+120
+2.5 -105
o39.5 -110
+114
+2.5 -114
o39.5 -115
+115
+2.5 -110
o39.5 -110
+118
+2.5 -110
o39.5 -110
Indianapolis Colts Colts
-140
-2.5 -115
u39.5 -110
-134
-2.5 -106
u39.5 -105
-140
-2.5 -110
u39.5 -110
-140
-2.5 -110
u39.5 -110