NFL Odds Week 16

The current Week 16 betting odds for the 2022 NFL season feature everything from short home underdogs to heavy road favorites. Whether it be Eagles vs Cowboys, Packers vs Dolphins or another one of the marquee matchups on this slate — Week 16 has a little something for everyone. Above all, though, Week 16 offers an opportunity for prospective bettors across the country to have a personal stake in the odds of the long-anticipated NFL season. At Lineups, we’ve dedicated our direct access to sportsbooks, data science avenues, and dedicated analysts to provide you with the most up-to-date information and analysis on week-by-week NFL odds. In the tables below, you’ll find odds comparisons from different sportsbooks as well as the best NFL odds on whichever side you believe has the edge.

DraftKings
FanDuel
BetMGM
Caesars
Game
DraftKings Odds
FanDuel Odds
BetMGM Odds
Caesars Odds
Date/Time Teams ML Spread O/U ML Spread O/U ML Spread O/U ML Spread O/U
12/23, 1:15 am GMT Jacksonville Jaguars Jaguars
+115
+2.5 -110
o- -
-
+1.5 -110
o46 -110
New York Jets Jets
-135
-2.5 -110
u- -
-
-1.5 -110
u46 -110
12/24, 6:00 pm GMT Atlanta Falcons Falcons
+350
+8.5 -110
o- -
-
+8 -110
o- -
Baltimore Ravens Ravens
-435
-8.5 -110
u- -
-
-8 -110
u- -
12/24, 6:00 pm GMT Detroit Lions Lions
+160
+4 -110
o- -
-
+3 -110
o- -
Carolina Panthers Panthers
-190
-4 -110
u- -
-
-3 -110
u- -
12/24, 6:00 pm GMT Buffalo Bills Bills
-490
-9 -110
o- -
-
-7.5 -110
o- -
Chicago Bears Bears
+390
+9 -110
u- -
-
+7.5 -110
u- -
12/24, 6:00 pm GMT New Orleans Saints Saints
+135
+3 -110
o- -
-
+2.5 -110
o- -
Cleveland Browns Browns
-155
-3 -110
u- -
-
-2.5 -110
u- -
12/24, 6:00 pm GMT Seattle Seahawks Seahawks
+470
+10.5 -110
o- -
-
+11 -110
o- -
Kansas City Chiefs Chiefs
-625
-10.5 -110
u- -
-
-11 -110
u- -
12/24, 6:00 pm GMT New York Giants Giants
+185
+5 -110
o- -
-
+5.5 -110
o- -
Minnesota Vikings Vikings
-215
-5 -110
u- -
-
-5.5 -110
u- -
12/24, 6:00 pm GMT Cincinnati Bengals Bengals
-120
-1 -110
o- -
New England Patriots Patriots
+100
+1 -110
u- -
12/24, 6:00 pm GMT Houston Texans Texans
+350
+8 -110
o- -
-
+7.5 -110
o- -
Tennessee Titans Titans
-435
-8 -110
u- -
-
-7.5 -110
u- -
12/24, 9:05 pm GMT Washington Commanders Commanders
+195
+6 -110
o- -
-
+7 -110
o- -
San Francisco 49ers 49ers
-230
-6 -110
u- -
-
-7 -110
u- -
12/24, 9:25 pm GMT Philadelphia Eagles Eagles
+150
+3.5 -110
o- -
-
+3 -110
o48.5 -110
Dallas Cowboys Cowboys
-175
-3.5 -110
u- -
-
-3 -110
u48.5 -110
12/25, 1:15 am GMT Las Vegas Raiders Raiders
-130
-1.5 -110
o- -
-
-2 -110
o- -
Pittsburgh Steelers Steelers
+110
+1.5 -110
u- -
-
+2 -110
u- -
12/25, 6:00 pm GMT Green Bay Packers Packers
-120
-1 -110
o- -
-
-1 -110
o48 -110
Miami Dolphins Dolphins
+100
+1 -110
u- -
-
+1 -110
u48 -110
12/25, 9:30 pm GMT Denver Broncos Broncos
+140
+3.5 -110
o49.5 -110
+122
+2.5 +100
o- -
-
+3 -110
o47 -110
Los Angeles Rams Rams
-165
-3.5 -110
u49.5 -110
-144
-2.5 -122
u- -
-
-3 -110
u47 -110
12/26, 1:20 am GMT Tampa Bay Buccaneers Buccaneers
-135
-2.5 -110
o- -
-
-2 -110
o52 -110
Arizona Cardinals Cardinals
+115
+2.5 -110
u- -
-
+2 -110
u52 -110
12/27, 1:15 am GMT Los Angeles Chargers Chargers
-120
-1 -110
o- -
-
PK -
o50.5 -110
Indianapolis Colts Colts
+100
+1 -110
u- -
-
PK -
u50.5 -110