NFL Odds Week 16

The current Week 16 betting odds for the 2022 NFL season feature everything from short home underdogs to heavy road favorites. Whether it be Eagles vs Cowboys, Packers vs Dolphins or another one of the marquee matchups on this slate — Week 16 has a little something for everyone. Above all, though, Week 16 offers an opportunity for prospective bettors across the country to have a personal stake in the odds of the long-anticipated NFL season. At Lineups, we’ve dedicated our direct access to sportsbooks, data science avenues, and dedicated analysts to provide you with the most up-to-date information and analysis on week-by-week NFL odds. In the tables below, you’ll find odds comparisons from different sportsbooks as well as the best NFL odds on whichever side you believe has the edge.

DraftKings
FanDuel
BetMGM
Caesars
Game
DraftKings Odds
FanDuel Odds
BetMGM Odds
Caesars Odds
Date/Time Teams ML Spread O/U ML Spread O/U ML Spread O/U ML Spread O/U
12/22, 1:15 am GMT New Orleans Saints Saints
-118
-1 -110
- -
-
-2.5 -110
- -
Los Angeles Rams Rams
-102
+1 -110
- -
-
+2.5 -110
- -
12/23, 9:30 pm GMT Cincinnati Bengals Bengals
-130
-2.5 -110
- -
-
-3 -110
- -
Pittsburgh Steelers Steelers
+110
+2.5 -110
- -
-
+3 -110
- -
12/24, 1:00 am GMT Buffalo Bills Bills
-115
-1 -110
- -
-
-1 -110
- -
Los Angeles Chargers Chargers
-105
+1 -110
- -
-
+1 -110
- -
12/24, 6:00 pm GMT Indianapolis Colts Colts
+124
+3 -110
- -
-
+3.5 -110
- -
Atlanta Falcons Falcons
-148
-3 -110
- -
-
-3.5 -110
- -
12/24, 6:00 pm GMT Green Bay Packers Packers
-115
-1 -110
- -
-
-1 -110
- -
Carolina Panthers Panthers
-105
+1 -110
- -
-
+1 -110
- -
12/24, 6:00 pm GMT Cleveland Browns Browns
-192
-4 -110
- -
-
-3.5 -110
- -
Houston Texans Texans
+160
+4 -110
- -
-
+3.5 -110
- -
12/24, 6:00 pm GMT Detroit Lions Lions
-102
+1 -110
- -
-
+1 -110
- -
Minnesota Vikings Vikings
-118
-1 -110
- -
-
-1 -110
- -
12/24, 6:00 pm GMT Washington Commanders Commanders
+185
+5.5 -110
- -
-
+6 -110
- -
New York Jets Jets
-225
-5.5 -110
- -
-
-6 -110
- -
12/24, 6:00 pm GMT Seattle Seahawks Seahawks
-125
-2 -110
- -
-
-2 -110
- -
Tennessee Titans Titans
+105
+2 -110
- -
-
+2 -110
- -
12/24, 9:05 pm GMT Jacksonville Jaguars Jaguars
-180
-3.5 -110
- -
-
-4 -110
- -
Tampa Bay Buccaneers Buccaneers
+150
+3.5 -110
- -
-
+4 -110
- -
12/24, 9:25 pm GMT Arizona Cardinals Cardinals
+164
+4.5 -110
- -
-
+5 -110
- -
Chicago Bears Bears
-198
-4.5 -110
- -
-
-5 -110
- -
12/24, 9:25 pm GMT Dallas Cowboys Cowboys
+102
+1.5 -110
- -
-
+1.5 -110
- -
Miami Dolphins Dolphins
-122
-1.5 -110
- -
-
-1.5 -110
- -
12/25, 1:15 am GMT New England Patriots Patriots
+105
+2 -110
- -
-
+3 -110
- -
Denver Broncos Broncos
-125
-2 -110
- -
-
-3 -110
- -
12/25, 6:00 pm GMT Las Vegas Raiders Raiders
+310
+8.5 -110
- -
+350
+9.5 -110
o51.5 -110
-
+9.5 -110
o51 -110
Kansas City Chiefs Chiefs
-395
-8.5 -110
- -
-450
-9.5 -110
u51.5 -110
-
-9.5 -110
u51 -110
12/25, 9:30 pm GMT New York Giants Giants
+245
+7 -110
- -
+285
+7.5 -105
o47 -110
-
+7.5 -110
o47 -110
Philadelphia Eagles Eagles
-305
-7 -110
- -
-355
-7.5 -115
u47 -110
-
-7.5 -110
u47 -110
12/26, 1:15 am GMT Baltimore Ravens Ravens
+130
+3 -110
- -
-
+3 -110
- -
San Francisco 49ers 49ers
-155
-3 -110
- -
-
-3 -110
- -