1:56 pm EDT, 8/15Highmark Stadium • Orchard Park, NY
Depth Chart
Buffalo Bills vs Carolina Panthers Matchup
Game Overview
Today's Odds
MoneylineSpreadOver/Under
BUF ML+106
BUF Spread-3 -108
O/U38.5 -109/-113
CAR Spread+3 -113
CAR ML+130
Odds ComparisonCARMLBUF
DraftKings+135####+111
Consensus+130####+106
William Hill+135####+111
FanDuel+126####+106
BetMGM+125####+105
Bet Splits
Panthers Vs. Bills Betting Record
Head To Head History
Last 6 Matchups
| 10/26/25 | vs | |||
| 12/19/21 | @ | |||
| 9/17/17 | vs | |||
| 9/15/13 | @ | |||
| 10/24/09 | vs | |||
| 11/26/05 | @ |
| 10/26/25 | vs | |||
| 12/19/21 | @ | |||
| 9/17/17 | vs | |||
| 9/15/13 | @ | |||
| 10/24/09 | vs | |||
| 11/26/05 | @ |
