MLB Game Betting Trends: Friday, September 25, 2026

Rays at Phillies Betting Trends

Venue Stats: Citizens Bank Park – 9.4 runs per game; 40-33-5 O/U

• Tampa Bay has lost 10 straight games when facing Philadelphia and coming off a loss. Tampa Bay is the underdog given a 41.7% chance to win.

• The road team has covered the run line in 9 of 11 games between Tampa Bay and Philadelphia. Tampa Bay is the road team with a 61.9% chance to cover +1.5-runs.

• Philadelphia Over 4 straight home games vs the AL East.

Mets at Nationals Betting Trends

Venue Stats: Nationals Park – 10.8 runs per game; 45-30-3 O/U

• New York has won 8 straight divisional games when facing a team under .500 and is the favorite, given a 57.4% chance to beat Washington.

• Washington has covered the run line in 5 of 6 games when facing New York and is given a 60% chance to cover +1.5-runs.

• New York Over 6 of 7 divisional games.

Orioles at Yankees Betting Trends

Venue Stats: Yankee Stadium – 8.8 runs per game; 39-36-3 O/U

• New York has won 9 straight home games when facing Baltimore and is the favorite, given a 59.2% chance to win.

• New York has covered the run line in 4 of 5 games against Baltimore and is given a 37% chance to cover -1.5-runs.

• New York Over 9 straight games vs the AL at night.

Reds at Blue Jays Betting Trends

Venue Stats: Rogers Centre – 8.3 runs per game; 39-36-3 O/U

• Cincinnati has lost 8 straight games when playing at night and coming off a win. Cincinnati is the underdog given a 46.5% chance to beat Toronto.

• Toronto has covered the run line in 5 of 7 games when facing Cincinnati and is given a 37.7% chance to cover -1.5-runs.

• The Over has hit in 7 straight meetings.

Braves at Marlins Betting Trends

Venue Stats: LoanDepot Park – 8.4 runs per game; 36-41-1 O/U

• Atlanta has won 12 straight game when facing Miami at night and coming off a loss. Atlanta is the favorite given a 55.6% chance to win.

• Atlanta has covered the run line in 6 straight games against Miami and is given a 42.6% chance to cover -1.5-runs.

• Miami Over 6 straight home games vs Atlanta.

Rockies at White Sox Betting Trends

Venue Stats: Rate Field – 9 runs per game; 44-33-1 O/U

• Colorado has lost 10 straight road games and is the underdog against Chicago, given a 35.1% chance to win.

• Chicago has failed to cover the run line in 8 straight games when facing the NL and faces Colorado, given a 53.5% chance to cover +1.5-runs.

• Chicago Over 4 straight games.

Guardians at Royals Betting Trends

Venue Stats: Kauffman Stadium – 9.8 runs per game; 38-38-2 O/U

• Kansas City has won 9 of 10 divisional home games when coming off a home loss but is the underdog despite this, given a 45.5% chance to beat Cleveland.

• The underdog has covered the run line in 5 of 6 games between Cleveland and Kansas City. Kansas City is the underdog given a 60% chance to cover +1.5-runs.

• Kansas City Over 5 straight divisional games.

Cardinals at Brewers Betting Trends

Venue Stats: American Family Field – 9 runs per game; 33-41-3 O/U

• Milwaukee has won 8 straight games when playing on a back-to-back at night and is the favorite, given a 64.9% chance to beat St. Louis.

• St. Louis has covered the run line in 4 of 6 games against Milwaukee and is given a 58.3% chance to cover +1.5-runs.

• St. Louis Under 4 straight games.

Rangers at Twins Betting Trends

Venue Stats: Target Field – 9.2 runs per game; 38-35-4 O/U

• Texas has lost 7 of 8 road games when facing the AL as the favorite and coming off a win. Texas is the favorite given a 52.8% chance to beat Minnesota.

• Minnesota has covered the run line in 9 straight games when facing the AL West as the underdog. Minnesota faces Texas as the underdog given a 64.9% chance to cover +1.5-runs.

• Texas Over 8 of 9 games vs the AL as a favorite.

Astros at Athletics Betting Trends

Venue Stats: Sutter Health Park – 11.4 runs per game; 45-24-3 O/U

• Houston has lost 6 straight games when coming off a win but is the favorite despite this, given a 63.6% chance to beat West Sacramento.

• The road team has covered the run line in 4 of 5 games between Houston and West Sacramento. Houston is the road team with a 49.5% chance to cover -1.5-runs.

• West Sacramento Over 10 straight divisional games.

Diamondbacks at Padres Betting Trends

Venue Stats: Petco Park – 7.8 runs per game; 33-40-5 O/U

• Arizona has won 7 of 8 games when playing on a back-to-back as the underdog. Arizona is the underdog given a 46.5% chance to beat San Diego.

• Arizona has covered the run line in 5 straight games and faces San Diego, given a 66.1% chance to cover +1.5-runs.

• San Diego Over 11 of 12 games as the favorite.

Angels at Mariners Betting Trends

Venue Stats: T-Mobile Park – 7.8 runs per game; 38-33-7 O/U

• Seattle has lost 9 straight games when facing the AL on a Friday but is the favorite despite this, given a 57.4% chance to beat Los Angeles.

• Los Angeles has covered the run line in 6 straight road games when playing as the underdog. Los Angeles faces Seattle as the underdog given a 67.2% chance to cover +1.5-runs.

• Los Angeles Over 5 straight road games.

Dodgers at Giants Betting Trends

Venue Stats: Oracle Park – 8.6 runs per game; 36-38-4 O/U

• San Francisco has lost 12 straight games when facing the NL on a Friday night and is the underdog, given a 25% chance to beat Los Angeles.

• Los Angeles has covered the run line in 5 straight games when facing San Francisco and is given a 68.3% chance to cover -1.5-runs.

• San Francisco Over 5 straight divisional games at night.