To Top

Houston Texans vs San Francisco 49ers Matchup

Game Overview

1:00 pm EDT, 10/26Reliant Stadium • Houston, TX

Depth Chart

12-5, 2nd NFC West

84RTG

San Francisco 49ers

12-5, 2nd AFC South

87RTG

Houston Texans

1:00 pm EDT, 10/26Reliant Stadium • Houston, TX

12-5, 2nd NFC West

84RTG

12-5, 2nd AFC South

87RTG

Depth Chart

San Francisco 49ers

Houston Texans

Today's Odds

MoneylineSpreadOver/Under

HOU ML+104

HOU Spread-3 -109

O/U41 -109/-108

SF Spread+3 -111

SF ML+134

Odds ComparisonSFMLHOU

DraftKings+130####+105

Consensus+134####+104

William Hill+130####+100

FanDuel+138####+104

BetMGM+130####+105

Bet Splits

49ers Vs. Texans Betting Record

WIN %

SPREAD %

O/U %

H/A %

SFHOU

Head To Head History

Last 6 Matchups

1/2/22	23	vs	7	ATS
12/10/17	26	@	16	ATS
10/6/13	34	vs	3	ATS
10/24/09	21	@	24	PUSH
12/31/05	20	vs	17	ATS
10/26/96	10	@	9	ATS

1/2/22	23	vs	7	ATS
12/10/17	26	@	16	ATS
10/6/13	34	vs	3	ATS
10/24/09	21	@	24	PUSH
12/31/05	20	vs	17	ATS
10/26/96	10	@	9	ATS

lineups.com publishes promotions, independent reviews, expert guides, and news about legal sports betting and gambling to help readers make informed decisions. We support responsible gambling and, where available, focus coverage on licensed and regulated operators.

For U.S. problem gambling help: call 1-800-GAMBLER or visit ncpgambling.org 21+ only. Please play responsibly.

For Alberta: 18+ only. Only play with operators authorised in your province. Gambling problem? Call the Addiction Helpline at 1-866-332-2322 (24/7). Please gamble responsibly.

For Ontario: 19+ only. Only play with operators authorised in your province. Gambling problem? Call ConnexOntario at 1-866-531-2600 (24/7). Please gamble responsibly.

Affiliate disclosure: Some links may earn us compensation. This doesn’t influence our editorial content. Offers and terms can change—always check the operator’s official terms.