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MLB Home Run Predictions, Picks, Props, Odds for Friday, June 12, 2026

Check out the best MLB home run picks and predictions for games scheduled on Friday, June 12 with odds and insights provided by Lineups.com.
Willson Contreras
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We made a small profit on Thursday, as Shohei Ohtani went yard, helping make up for losses on Kyle Tucker and Randy Arozarena.

Today, we’re going with Colton Cowser, Kyle Manzardo, and Willson Contreras. Each of these hitters has been hot at the plate, so I like the spot for them.

Remember to be sure to check out our daily MLB betting trends page.

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2026 MLB HR Props Record: 44-173 (+0.94 units) 

Home Run Prop Predictions & Odds: MLB HR Best Bets for Friday, June 12

Colton Cowser Home Run Odds

Colton Cowser is slashing .227/.311/.397 with seven home runs in 162 plate appearances. While that’s an underwhelming slash line, Cowser has been swinging a hot bat of late. In the last 14 days, Cowser has four home runs with a 164 wRC+ in 45 plate appearances.

Up next is an exploitable matchup against Padres’ right-hander Griffin Canning, who has struggled this year, putting up a 4.46 xERA and 10.1% barrel rate. Home runs have been a major issue for Canning, as highlighted by his 1.65 HR/9. On top of that, lefties like Cowser have crushed Canning, putting up a .404 wOBA, compared to .260 wOBA vs. righties.

Add in the fact that this game is in a hitter-friendly environment in Camden Yards, and you have to like the spot for Cowser to hit his eighth home run of the season. Risk 0.1 units.

Kyle Manzardo Home Run Odds

Kyle Manzardo is currently slashing .235/.325/.399 with seven home runs in 209 plate appearances. This has been a disappointing start to the season, but at least he’s hitting the ball hard, as highlighted by a 12.1% barrel rate. He’s also been hot at the plate lately. In the last 14 days, Manzardo has a 169 wRC+ with two home runs in 40 plate appearances.

Up next is a matchup against Jack Flaherty, who has a 4.56 xERA and 9.0% barrel rate allowed on the season. Home runs have been a bit of an issue for Flaherty, as he’s allowing a 1.15 HR/9. Additionally, lefties like Manzardo have been much better against Flaherty (.371 wOBA) compared to righties (.332 wOBA).

When you consider how locked in Manzardo has been at the plate, then factor in this matchup, you have to like the spot for the Guardians’ first baseman to hit No. 8 tonight. Risk 0.1 units.

Willson Contreras Home Run Odds

Willson Contreras is currently slashing .284/.381/.516 with 13 home runs in 265 plate appearances. He’s quietly been a rock-solid pickup for the Red Sox, hitting the ball hard with a 14.9% barrel rate. In the last 14 days, Contreras has a 146 wRC+ with two home runs in 42 plate appearances, so he’s been swinging the bat well right now.

Up next is a matchup against Jack Leiter, who has a 4.56 xERA and an 11.1% barrel rate allowed this season. He continues to have an issue with the long ball, as highlighted by a 1.39 HR/9.

This game is in a hitter-friendly environment at Fenway Park as well, so I like Contreras’ chances of hitting his 14th homer of the season tonight. Risk 0.1 units.

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About the Author
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Frank Ammirante

Senior Staff Writer

Frank Ammirante has spent the last 5+ years covering sports betting, fantasy sports, and the wider iGaming industry, with a focus on MLB and NFL betting alongside fantasy baseball and football strategy, as well as basketball, hockey, and soccer. His work has appeared on outlets like The Game Day, RotoBaller, FantasyPros, Deadspin, and Pro Football Network, and more, where he's covered everything from player props and betting futures to online casino and sweepstakes casino reviews, prediction markets, and industry news. He also brings hands-on editorial experience as a content editor elsewhere in the industry. Frank started out in the fantasy sports space, and today he's a member of the Fantasy Sports Writers Association who competes in some of the industry's toughest expert fantasy leagues, including Tout Wars, Scott Fish Bowl, and The Great Fantasy Baseball Invitational. He's an annual competitor in Tout Wars specifically, and his fantasy baseball rankings have been featured in Fantasy Index's fantasy baseball magazine. Off the clock, he's a die-hard Toronto Blue Jays and Washington Commanders fan who still isn't quite over the Blue Jays' World Series loss to the Dodgers, which he's called "one of the biggest collapses in sports history."

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