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MLB Home Run Predictions, Picks, Props, Odds for Friday, May 29, 2026

Check out the best MLB home run picks and predictions for games scheduled on Friday, May 29 with odds and insights from Lineups.com.
Eugenio Suarez
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We had another winning night on Thursday, as Bryan Reynolds cashed a +750 home run prop to make it a profitable evening, even with George Springer and Pete Alonso failing to go yard.

Today, we’re going with Eugenio Suarez, Michael Busch, and Jazz Chisholm Jr. Each of these hitters is in a good spot to hit a home run.

Remember to be sure to check out our daily MLB betting trends page.

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2026 MLB HR Props Record: 35-144 (-0.2 units) 

Home Run Prop Predictions & Odds: MLB HR Best Bets for Friday, May 29

Eugenio Suarez Home Run Odds

Eugenio Suarez has had an injury-plagued start to the season in his first year back with the Reds. The veteran slugger is slashing .238/.322/.371 with three home runs in 118 plate appearances. However, this is a power hitter with a long track record, including 49 home runs last year, so it’s only a matter of time before he gets rolling.

We’re starting to see signs of a hot streak, as Suarez has two multi-hit games in his last three. In a home game in the bandbox that is Great American Ball Park, this could be a good spot for Suarez to hit No. 4.

It also bodes well that the matchup is against Braves’ right-hander Grant Holmes, who has had issues with the long ball this year, as highlighted by a 1.55 HR/9. Suarez has terrific numbers vs. Holmes in his career, including three home runs and a 1.415 expected slugging percentage in six plate appearances.

With that in mind, we’ll ride with Suarez in this spot. Risk 0.1 units.

Michael Busch Home Run Odds

Michael Busch broke out with 36 home runs last year. So far this season, it’s been a slow start, including a .229/.367/.383 slash with six home runs in 248 plate appearances. The good news is that Busch is still hitting the ball hard, putting up a 12.8% barrel rate, so the power binge could be coming soon.

We’ve seen the Cubs’ first baseman hit two home runs in his last five games. Perhaps this is the start of a hot streak, so we’re going to hop on board now.

I like the matchup vs. Cardinals’ right-hander Kyle Leahy. The main appeal here is how much Leahy has struggled against left-handed hitters this season. They’re putting up a .425 wOBA against him, while righties are only at .297 wOBA.

I can’t pass up that kind of batter-vs-pitcher data here, especially since Busch is showing signs of life at the plate. Risk 0.1 units.

Jazz Chisholm Jr. Home Run Odds

Jazz Chisholm Jr. is another hitter who has gotten off to a slow start, slashing .246/.324/.400 with six home runs in 219 plate appearances. The barrel rate is way down, falling from 15.0% to 6.0%, but I trust in Chisholm’s track record as a hitter with 30-homer upside.

He’s also really heating up at the plate. In his last 12 games, he’s gone 18-for-51 (.353 BA) with two home runs. That bodes well for tonight’s matchup, which is at one of the most hitter-friendly environments against the Athletics at Sutter Health Park.

Chisholm will be going up against Athletics’ right-hander Luis Severino. The career numbers look good, as Jazz has two home runs with a .685 expected slugging percentage against Severino in 14 plate appearances.

Considering how well Jazz is swinging the bat, you have to like this spot in a hitter’s park against a pitcher he’s dominated. Risk 0.1 units.

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About the Author
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Frank Ammirante

Senior Staff Writer

Frank Ammirante has spent the last 5+ years covering sports betting, fantasy sports, and the wider iGaming industry, with a focus on MLB and NFL betting alongside fantasy baseball and football strategy, as well as basketball, hockey, and soccer. His work has appeared on outlets like The Game Day, RotoBaller, FantasyPros, Deadspin, and Pro Football Network, and more, where he's covered everything from player props and betting futures to online casino and sweepstakes casino reviews, prediction markets, and industry news. He also brings hands-on editorial experience as a content editor elsewhere in the industry. Frank started out in the fantasy sports space, and today he's a member of the Fantasy Sports Writers Association who competes in some of the industry's toughest expert fantasy leagues, including Tout Wars, Scott Fish Bowl, and The Great Fantasy Baseball Invitational. He's an annual competitor in Tout Wars specifically, and his fantasy baseball rankings have been featured in Fantasy Index's fantasy baseball magazine. Off the clock, he's a die-hard Toronto Blue Jays and Washington Commanders fan who still isn't quite over the Blue Jays' World Series loss to the Dodgers, which he's called "one of the biggest collapses in sports history."

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