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MLB Home Run Predictions, Picks, Props, Odds for Saturday, April 25, 2026

Check out the best MLB home run picks and predictions for games on Saturday, April 25 with odds and insights provided by Lineups.com.
Riley Greene
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We had a small profit on Friday, as Ronald Acuña Jr. hit a home run. Let’s try to build on that with another winning night on Saturday.

Today, we’re going with Aaron Judge, Kyle Schwarber, and Riley Greene. Each of these hitters is in great spots.

Keep reading to find out about our MLB home run predictions for today. Also, be sure to check out our daily MLB betting trends page.

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2026 MLB HR Props Record: 12-70 (-1.61 units) 

Home Run Prop Predictions & Odds: MLB HR Best Bets for Saturday, April 25

Aaron Judge Home Run Odds

Aaron Judge is currently slashing .237/.372/.559 with nine home runs in 114 plate appearances. The batted ball metrics are bonkers, with a 24.2% barrel rate.

Despite the Yankees pouring on runs last night, Judge didn’t homer. But I’m going back to him for the second consecutive night just because Houston is a great spot for right-handed power hitters with the Crawford boxes in left field.

It’s another exploitable pitching matchup here with Mike Burrows on the mound. The Astros’ righty is allowing a 1.69 HR/9 this season.

The price is always inflated on Judge, but at least we’re getting him at longer than +200 odds here. Risk 0.1 units.

Kyle Schwarber Home Run Odds

Kyle Schwarber is currently slashing .189/.336/.484 with eight home runs in 116 plate appearances. It’s been a poor start at the plate, but he still has a 21.8% barrel rate, so I’m not too concerned.

We’re getting some wind blowing out to left field with 71-degree temperatures for this game, so it’s slightly favorable hitting weather. You also have to like the pitching matchup against right-hander Bryce Elder.

While he’s off to a great start with a 1.50 ERA, that comes with a 3.65 SIERA. It’s only a matter of time before we see some regression.

We’ll take Schwarber to go yard to help the Phillies snap this 10-game losing streak. Risk 0.1 units.

Riley Greene Home Run Odds

We’ll finish it off with Riley Greene to hit a home run. The Tigers’ slugger is currently slashing .295/.396/.474 with three home runs in 111 plate appearances. It’s impressive how he’s trimmed his strikeout rate from 30.7% to 23.4%. The batted ball metrics also look great with a 14.5% barrel rate.

Perhaps Greene is taking the next step as a hitter.

It’s also worth noting that Greene is coming into this game on a hot streak, going 10-for-26 with homers in back-to-back games on his current six-game hitting streak. This includes three two-hit games in a row and four in his last five.

It’s a great spot at one of the most hitter-friendly environments in baseball in Great American Ball Park, especially with 7 MPH winds blowing out to right field.

The pitching matchup looks good as well with Brady Singer on the mound. The veteran righty has a 5.18 xERA and 44.7% hard-hit rate.

So, here we have the perfect storm for a home run prop: improving hitter on a hot streak, facing a struggling pitcher in a hitter-friendly environment.  Risk 0.1 units.

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About the Author
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Frank Ammirante

Senior Staff Writer

Frank Ammirante has spent the last 5+ years covering sports betting, fantasy sports, and the wider iGaming industry, with a focus on MLB and NFL betting alongside fantasy baseball and football strategy, as well as basketball, hockey, and soccer. His work has appeared on outlets like The Game Day, RotoBaller, FantasyPros, Deadspin, and Pro Football Network, and more, where he's covered everything from player props and betting futures to online casino and sweepstakes casino reviews, prediction markets, and industry news. He also brings hands-on editorial experience as a content editor elsewhere in the industry. Frank started out in the fantasy sports space, and today he's a member of the Fantasy Sports Writers Association who competes in some of the industry's toughest expert fantasy leagues, including Tout Wars, Scott Fish Bowl, and The Great Fantasy Baseball Invitational. He's an annual competitor in Tout Wars specifically, and his fantasy baseball rankings have been featured in Fantasy Index's fantasy baseball magazine. Off the clock, he's a die-hard Toronto Blue Jays and Washington Commanders fan who still isn't quite over the Blue Jays' World Series loss to the Dodgers, which he's called "one of the biggest collapses in sports history."

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