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MLB Home Run Predictions, Picks, Props, Odds for Thursday, April 16, 2026

Check out the best MLB home run picks and predictions for games on Thursday, April 16 with odds and insights from Lineups.com.
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We missed on Cody Bellinger, Mike Yastrzemski, and Lawrence Butler as our home run picks on Wednesday. We’ll look to get back in the winning column on Thursday’s slate.

Today, we’re going with Jose Ramirez, Christian Walker, and Cal Raleigh. We’re laying more chalk for this slate because not only are there fewer options, but we need a profitable night after what’s been an ice-cold start to the year.

Keep reading to find out about our MLB home run predictions for today. Also, be sure to check out our daily MLB betting trends page.

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2026 MLB HR Props Record: 5-50 (-2.45 units) 

Home Run Prop Predictions & Odds: MLB HR Best Bets for Thursday, April 16

Jose Ramirez Home Run Odds

Jose Ramirez is currently slashing .205/.301/.384 with three home runs in 83 plate appearances. It’s been a slow start to the season, but he’s slowly starting to heat up. The veteran third baseman has gone 7-for-23 (.304) with two home runs in his last five games.

As one of the most consistent hitters in baseball with four 30+ home run seasons under his belt, it’s only a matter of time before Ramirez starts to get rolling at the plate.

I’ll take a shot that he can go yard in a favorable matchup against Orioles’ right-hander Shane Baz, who is giving up a lot of hard contact this season, including a 9.8% barrel rate, which ranks in the 37th percentile.

Baz struggled with the long ball last year (1.41 HR/9), so we’ll take a shot on Ramirez taking him deep. Risk 0.1 units.

Christian Walker Home Run Odds

Christian Walker looks like he’s in the middle of a resurgence after a down year in his debut season with the Astros in 2025. The veteran first baseman is currently slashing .303/.382/.576 with four home runs in 76 plate appearances.

This is supported by excellent batted ball metrics, including an impressive 14.3% barrel rate. Walker has four home runs in his last 11 games, so he’s been rolling at the plate.

The Rockies are using an opener in Juan Mejia (.321 xBA allowed), followed by Chase Dollander (16.3% barrel rate), so it’s a good spot for Walker to hit his fifth home run of the season.

It’s always a good idea to try to target Rockies’ pitching. Risk 0.1 units.

Cal Raleigh Home Run Odds

Cal Raleigh is off to a slow start following his historic 2025 season, slashing .151/.241/.274 with two home runs in 83 plate appearances. However, both of those homers came in his last nine games, so perhaps he’s slowly starting to get on track.

Even though a repeat of 60 home runs is extremely unlikely for Raleigh, you’re still likely going to see 35+, which means that it’s only a matter of time before we see a power binge.

Up next is a good spot against Padres’ right-hander Walker Buehler. We’ve seen Raleigh have success against the former Dodger throughout his career, including one home run and two doubles in six plate appearances. Within this small sample, Raleigh has an impressive .719 expected slugging percentage.

With that in mind, we’ll take a shot on Raleigh to hit No. 3 tonight. Risk 0.1 units.

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About the Author
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Frank Ammirante

Senior Staff Writer

Frank Ammirante has spent the last 5+ years covering sports betting, fantasy sports, and the wider iGaming industry, with a focus on MLB and NFL betting alongside fantasy baseball and football strategy, as well as basketball, hockey, and soccer. His work has appeared on outlets like The Game Day, RotoBaller, FantasyPros, Deadspin, and Pro Football Network, and more, where he's covered everything from player props and betting futures to online casino and sweepstakes casino reviews, prediction markets, and industry news. He also brings hands-on editorial experience as a content editor elsewhere in the industry. Frank started out in the fantasy sports space, and today he's a member of the Fantasy Sports Writers Association who competes in some of the industry's toughest expert fantasy leagues, including Tout Wars, Scott Fish Bowl, and The Great Fantasy Baseball Invitational. He's an annual competitor in Tout Wars specifically, and his fantasy baseball rankings have been featured in Fantasy Index's fantasy baseball magazine. Off the clock, he's a die-hard Toronto Blue Jays and Washington Commanders fan who still isn't quite over the Blue Jays' World Series loss to the Dodgers, which he's called "one of the biggest collapses in sports history."

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