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MLB Home Run Predictions, Picks, Props, Odds for Wednesday, June 10, 2026

Check out the best MLB home run picks and predictions for games scheduled on Wednesday, June 10 with insights provided by Lineups.com.
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Frank Ammirante Avatar
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We had a profitable night on Tuesday, as Randy Arozarena went yard, helping make up for losses on Marcell Ozuna and Wyatt Langford. Let’s make it two winning nights in a row on the Wednesday slate. We’ve been hot lately.

Today, we’re going with Jose Altuve, Randal Grichuk, and Corey Seager. Each of these hitters is in a good spot to hit a home run, including favorable prices.

Remember to be sure to check out our daily MLB betting trends page.

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2026 MLB HR Props Record: 43-168 (+1.19 units) 

Home Run Prop Predictions & Odds: MLB HR Best Bets for Wednesday, June 10

Jose Altuve Home Run Odds

Jose Altuve is a veteran hitter with a strong track record, but he hasn’t gotten it going in his age-36 season, slashing .237/.320/.379 with five home runs in 201 plate appearances.

It’s been a year plagued by injury so far, as Altuve recently returned to action on June 5th.

But one thing Altuve has always done is hit lefties, putting up a 146 wRC+ against them throughout his career (121 wRC+ vs. righties).

He’ll get one tonight in Angels’ left-hander Reid Detmers. While Detmers has an impressive 2.92 xERA on the season, Altuve has had success against him throughout his career, putting up two home runs in 24 plate appearances.

With that in mind, we’ll take a shot on Altuve to hit No. 6 in this spot. Risk 0.1 units.

Randal Grichuk Home Run Odds

Randal Grichuk is currently slashing .267/.297/.547 with six home runs in 91 plate appearances. He’s been an absolute lefty masher this season, putting up a 193 wRC+ against them. At this stage of his career, he’s a weak-side platoon specialist.

We recently saw Grichuk hit two home runs on June 5th. I’ll bet on him to do it again in this spot.

It’s a tough matchup against Chris Sale, who has a 3.33 xERA on the season. However, Grichuk is quite familiar with Sale, homering twice in 30 plate appearances against him.

We’re getting a nicer price here given the tough matchup, so we’ll take a shot on Grichuk in this spot. Risk 0.1 units.

Corey Seager Home Run Odds

Corey Seager is having another disappointing season that has been plagued by injury, currently slashing .185/.284/.363 with eight home runs in 194 plate appearances.

The good news is that he’s hitting the ball hard, including a 15.4% barrel rate, which aligns with his career norms, so there’s no decline there.

I like the matchup in a hitter-friendly environment at Kauffman Stadium tonight. He’s going up against veteran right-hander Seth Lugo, who has a 5.23 xERA on the season.

What’s good about this spot is that Seager has one home run and a .607 expected slugging percentage against Lugo, so there’s some familiarity here.

We recently saw Seager go yard on June 5th, so perhaps he’s slowly getting into a groove. Risk 0.1 units.

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About the Author
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Frank Ammirante

Senior Staff Writer

Frank Ammirante has spent the last 5+ years covering sports betting, fantasy sports, and the wider iGaming industry, with a focus on MLB and NFL betting alongside fantasy baseball and football strategy, as well as basketball, hockey, and soccer. His work has appeared on outlets like The Game Day, RotoBaller, FantasyPros, Deadspin, and Pro Football Network, and more, where he's covered everything from player props and betting futures to online casino and sweepstakes casino reviews, prediction markets, and industry news. He also brings hands-on editorial experience as a content editor elsewhere in the industry. Frank started out in the fantasy sports space, and today he's a member of the Fantasy Sports Writers Association who competes in some of the industry's toughest expert fantasy leagues, including Tout Wars, Scott Fish Bowl, and The Great Fantasy Baseball Invitational. He's an annual competitor in Tout Wars specifically, and his fantasy baseball rankings have been featured in Fantasy Index's fantasy baseball magazine. Off the clock, he's a die-hard Toronto Blue Jays and Washington Commanders fan who still isn't quite over the Blue Jays' World Series loss to the Dodgers, which he's called "one of the biggest collapses in sports history."

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