San Francisco 49ers Schedule 2022 San Francisco 49ers Schedule

0-0, T-1st NFC West

@ CHI

5:00 pm GMT , 9/11

9/11, 5:00p
9/11, 5:00p
SF
49ers
CHI
Bears
The 49ers play in the NFC West and face the AFC West this year, so they are tied for the fifth-most difficult schedule in the NFL this year. Combine that with expected growing pains for Trey Lance in his first year as a starter, and it could be a tough year for Kyle Shanahan’s team. The first two games are easy enough against the Bears (road) and Seahawks (home), but rom there it gets more difficult with two primetime games against the Broncos (road) and Rams (home). The most difficult stretch of the season comes starting in Week 7 when the Niners play the Chiefs (home), Rams (road), and Chargers (home), but they luckily have their bye week between those Rams and Chargers matchups. The final four weeks of the season set up nicely with the Seahawks (road), Commanders (home), Raiders (road), and Cardinals (home), and if Lance gets better as the year goes on that late-season stretch could catapult the 49ers into another deep playoff run.
WK Date Time TV Opponent Stadium Record Opponent Depth Chart 49ers Depth Chart Matchup
1 9/11/22 5:00 pm FOX at Chicago Bears CHI Bears Chicago Bears Soldier Field 0 - 0 CHI Bears Chicago Bears SF 49ers San Francisco 49ers 49ers at Bears
2 9/18/22 8:05 pm FOX vs Seattle Seahawks SEA Seahawks Seattle Seahawks Levi's Stadium 0 - 0 SEA Seahawks Seattle Seahawks SF 49ers San Francisco 49ers
3 9/26/22 12:20 am NBC at Denver Broncos DEN Broncos Denver Broncos Empower Field at Mile High 0 - 0 DEN Broncos Denver Broncos SF 49ers San Francisco 49ers
4 10/4/22 12:15 am ESPN vs Los Angeles Rams LAR Rams Los Angeles Rams Levi's Stadium 0 - 0 LAR Rams Los Angeles Rams SF 49ers San Francisco 49ers
5 10/9/22 8:05 pm CBS at Carolina Panthers CAR Panthers Carolina Panthers Bank of America Stadium 0 - 0 CAR Panthers Carolina Panthers SF 49ers San Francisco 49ers
6 10/16/22 5:00 pm FOX at Atlanta Falcons ATL Falcons Atlanta Falcons Mercedes-Benz Stadium 0 - 0 ATL Falcons Atlanta Falcons SF 49ers San Francisco 49ers
7 10/23/22 8:25 pm FOX vs Kansas City Chiefs KC Chiefs Kansas City Chiefs Levi's Stadium 0 - 0 KC Chiefs Kansas City Chiefs SF 49ers San Francisco 49ers
8 10/30/22 8:25 pm FOX at Los Angeles Rams LAR Rams Los Angeles Rams SoFi Stadium 0 - 0 LAR Rams Los Angeles Rams SF 49ers San Francisco 49ers
9 BYE WEEK
10 11/14/22 1:20 am NBC vs Los Angeles Chargers LAC Chargers Los Angeles Chargers Levi's Stadium 0 - 0 LAC Chargers Los Angeles Chargers SF 49ers San Francisco 49ers
11 11/22/22 1:15 am ESPN at Arizona Cardinals ARI Cardinals Arizona Cardinals Estadio Azteca 0 - 0 ARI Cardinals Arizona Cardinals SF 49ers San Francisco 49ers
12 11/27/22 9:25 pm FOX vs New Orleans Saints NO Saints New Orleans Saints Levi's Stadium 0 - 0 NO Saints New Orleans Saints SF 49ers San Francisco 49ers
13 12/4/22 9:05 pm FOX vs Miami Dolphins MIA Dolphins Miami Dolphins Levi's Stadium 0 - 0 MIA Dolphins Miami Dolphins SF 49ers San Francisco 49ers
14 12/11/22 9:25 pm FOX vs Tampa Bay Buccaneers TB Buccaneers Tampa Bay Buccaneers Levi's Stadium 0 - 0 TB Buccaneers Tampa Bay Buccaneers SF 49ers San Francisco 49ers
15 12/16/22 1:15 am at Seattle Seahawks SEA Seahawks Seattle Seahawks Lumen Field 0 - 0 SEA Seahawks Seattle Seahawks SF 49ers San Francisco 49ers
16 12/24/22 9:05 pm CBS vs Washington Commanders WAS Commanders Washington Commanders Levi's Stadium 0 - 0 WAS Commanders Washington Commanders SF 49ers San Francisco 49ers
17 1/1/23 9:05 pm FOX at Las Vegas Raiders OAK Raiders Las Vegas Raiders Allegiant Stadium 0 - 0 OAK Raiders Las Vegas Raiders SF 49ers San Francisco 49ers
18 1/8/23 6:00 am vs Arizona Cardinals ARI Cardinals Arizona Cardinals Levi's Stadium 0 - 0 ARI Cardinals Arizona Cardinals SF 49ers San Francisco 49ers