San Francisco 49ers Schedule 2021 San Francisco 49ers Schedule

10-7, 3rd NFC West

@ DAL

9:30 pm GMT , 1/16

1/16, 9:30p
1/16, 9:30p
SF
49ers
DAL
Cowboys

Many are calling for a Super Bowl hangover with the San Francisco 49ers as they have a division that is very tough, especially with the Cardinals making their moves over the offseason. They are in the bottom half for strength of schedule, but there are a lot of matchups that can go either way. San Francisco will start out at home facing the Arizona Cardinals, before things get a little easier. They go on the road for both of the next two weeks, as they have both the Giants and the Jets. This is not a bad road schedule to get out of the way, especially factoring in you are in the same state. San Francisco will welcome the Eagles on Sunday Night for Week 4, and then have an easy home matchup against the Dolphins next. The middle of the season is where things get tough for San Francisco, as they will go on the road against the Patriots, Seahawks, and Saints all before their Bye Week. Their home games are against the Packers and Rams. Coming out of the bye week they face the Rams and then are at home against the Bills. Week 15 is going to be circled as they face the Cowboys, and then have the Cardinals and Seahawks on the schedule.

Date Time Opponent Stadium Score Record Matchup
1/9/22 9:25 pm at Los Angeles Rams Los Angeles Rams SoFi Stadium 27-24 10 - 7 San Francisco 49ers 49ers at Los Angeles Rams Rams
1/2/22 9:05 pm vs Houston Texans Houston Texans Levi's Stadium 23-7 9 - 7 San Francisco 49ers 49ers vs Houston Texans Texans
12/24/21 1:20 am at Tennessee Titans Tennessee Titans Nissan Stadium 17-20 8 - 7 San Francisco 49ers 49ers at Tennessee Titans Titans
12/19/21 9:05 pm vs Atlanta Falcons Atlanta Falcons Levi's Stadium 31-13 8 - 6 San Francisco 49ers 49ers vs Atlanta Falcons Falcons
12/12/21 9:25 pm at Cincinnati Bengals Cincinnati Bengals Paul Brown Stadium 26-23 7 - 6 San Francisco 49ers 49ers at Cincinnati Bengals Bengals
12/5/21 9:25 pm at Seattle Seahawks Seattle Seahawks Lumen Field 23-30 6 - 6 San Francisco 49ers 49ers at Seattle Seahawks Seahawks
11/28/21 9:25 pm vs Minnesota Vikings Minnesota Vikings Levi's Stadium 34-26 6 - 5 San Francisco 49ers 49ers vs Minnesota Vikings Vikings
11/21/21 6:00 pm at Jacksonville Jaguars Jacksonville Jaguars TIAA Bank Field 30-10 5 - 5 San Francisco 49ers 49ers at Jacksonville Jaguars Jaguars
11/16/21 1:15 am vs Los Angeles Rams Los Angeles Rams Levi's Stadium 31-10 4 - 5 San Francisco 49ers 49ers vs Los Angeles Rams Rams
11/7/21 9:25 pm vs Arizona Cardinals Arizona Cardinals Levi's Stadium 17-31 3 - 5 San Francisco 49ers 49ers vs Arizona Cardinals Cardinals
10/31/21 5:00 pm at Chicago Bears Chicago Bears Soldier Field 33-22 3 - 4 San Francisco 49ers 49ers at Chicago Bears Bears
10/25/21 12:20 am vs Indianapolis Colts Indianapolis Colts Levi's Stadium 18-30 2 - 4 San Francisco 49ers 49ers vs Indianapolis Colts Colts
10/10/21 8:25 pm at Arizona Cardinals Arizona Cardinals State Farm Stadium 10-17 2 - 3 San Francisco 49ers 49ers at Arizona Cardinals Cardinals
10/3/21 8:05 pm vs Seattle Seahawks Seattle Seahawks Levi's Stadium 21-28 2 - 2 San Francisco 49ers 49ers vs Seattle Seahawks Seahawks
9/27/21 12:20 am vs Green Bay Packers Green Bay Packers Levi's Stadium 28-30 2 - 1 San Francisco 49ers 49ers vs Green Bay Packers Packers
9/19/21 5:00 pm at Philadelphia Eagles Philadelphia Eagles Lincoln Financial Field 17-11 2 - 0 San Francisco 49ers 49ers at Philadelphia Eagles Eagles
9/12/21 5:00 pm at Detroit Lions Detroit Lions Ford Field 41-33 1 - 0 San Francisco 49ers 49ers at Detroit Lions Lions