San Francisco 49ers Schedule 2024-25 San Francisco 49ers Schedule
0-0, T-1st NFC West
@ SEA
8:05 pm GMT, 9/7
The 49ers went into the playoffs with a very challenging QB situation, and while they’ve had an offseason to prepare, the position is still a question mark. They’ll start figuring things out right away, as the 49ers 2023 schedule provides them with plenty of tests straight from the start. They open on the road in a tough Pittsburgh environment, and then head to LA for a clash with the division rival Rams. Then there’s a matchup with a fellow 2022 playoff team, the Giants, one of five 49ers primetime games. The regular season will wrap up with a couple of intriguing late home games, in week 16 against the Ravens and then the season finale against the Rams. A lot of people are split on this team coming into the season, but they have plenty of talent and a friendly enough schedule to get very solid playoff seeding.
| WK | Date | Time | Opponent | Spread | Moneyline | Total | Score | Record | Matchup |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 9/10/24 | 12:15 am | vs  NYJ Jets New York Jets | SF -3.5 | NYJ +160/SF -192 | O/U 43.0 | 32-19 | 1 - 0 | 49ers vs Jets |
| 2 | 9/15/24 | 5:00 pm | at  MIN Vikings Minnesota Vikings | SF -4.5 | SF -218/MIN +180 | O/U 46.5 | 17-23 | 1 - 1 | 49ers at Vikings |
| 3 | 9/22/24 | 8:25 pm | at  LAR Rams Los Angeles Rams | SF -6.0 | SF -258/LAR +210 | O/U 44.5 | 24-27 | 1 - 2 | 49ers at Rams |
| 4 | 9/29/24 | 8:05 pm | vs  NE Patriots New England Patriots | SF -10.5 | NE +425/SF -575 | O/U 42.5 | 30-13 | 2 - 2 | 49ers vs Patriots |
| 5 | 10/6/24 | 8:05 pm | vs  ARI Cardinals Arizona Cardinals | SF -7.5 | ARI +270/SF -340 | O/U 49.0 | 23-24 | 2 - 3 | 49ers vs Cardinals |
| 6 | 10/11/24 | 12:15 am | at  SEA Seahawks Seattle Seahawks | SF -3.5 | SF -198/SEA +164 | O/U 49.0 | 36-24 | 3 - 3 | 49ers at Seahawks |
| 7 | 10/20/24 | 8:25 pm | vs  KC Chiefs Kansas City Chiefs | SF -2.5 | KC +124/SF -142 | O/U 48.0 | 18-28 | 3 - 4 | 49ers vs Chiefs |
| 8 | 10/28/24 | 12:20 am | vs  DAL Cowboys Dallas Cowboys | SF -5.5 | DAL +195/SF -238 | O/U 48.0 | 30-24 | 4 - 4 | 49ers vs Cowboys |
| 9 | BYE WEEK | ||||||||
| 10 | 11/10/24 | 6:00 pm | at  TB Buccaneers Tampa Bay Buccaneers | SF -6.5 | SF -298/TB +240 | O/U 50.5 | 23-20 | 5 - 4 | 49ers at Buccaneers |
| 11 | 11/17/24 | 9:05 pm | vs SEA Seahawks Seattle Seahawks | SF -6.0 | SEA +210/SF -258 | O/U 48.5 | 17-20 | 5 - 5 | 49ers vs Seahawks |
| 12 | 11/24/24 | 9:25 pm | at  GB Packers Green Bay Packers | GB -6.5 | SF +235/GB +110 | O/U 44.5 | 10-38 | 5 - 6 | 49ers at Packers |
| 13 | 12/2/24 | 1:20 am | at  BUF Bills Buffalo Bills | BUF -6.5 | SF +275/BUF +105 | O/U 45.5 | 10-35 | 5 - 7 | 49ers at Bills |
| 14 | 12/8/24 | 9:25 pm | vs  CHI Bears Chicago Bears | SF -3.0 | CHI +136/SF -162 | O/U 43.5 | 38-13 | 6 - 7 | 49ers vs Bears |
| 15 | 12/13/24 | 1:15 am | vs LAR Rams Los Angeles Rams | SF -3.0 | LAR +130/SF -155 | O/U 48.5 | 6-12 | 6 - 8 | 49ers vs Rams |
| 16 | 12/22/24 | 9:25 pm | at  MIA Dolphins Miami Dolphins | SF -2.0 | SF +100/MIA +105 | O/U 44.0 | 17-29 | 6 - 9 | 49ers at Dolphins |
| 17 | 12/31/24 | 1:15 am | vs  DET Lions Detroit Lions | DET -4.0 | DET +170/SF +185 | O/U 50.5 | 34-40 | 6 - 10 | 49ers vs Lions |
| 18 | 1/5/25 | 9:25 pm | at ARI Cardinals Arizona Cardinals | ARI -5.5 | SF +185/ARI +164 | O/U 43.5 | 24-47 | 6 - 11 | 49ers at Cardinals |