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New England Patriots vs. Seattle Seahawks Game Preview, Picks & Odds for Wednesday, September 9, 2026

Check out the NFL game preview for the Patriots vs. Seahawks set for Wednesday, September 9 with odds and picks provided by Lineups.com.
J Smith-Njigba
Thom Cunningham Avatar
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The NFL season kicks off on a Wednesday this season, with a rematch from the Super Bowl as the New England Patriots will face the Seattle Seahawks. Let’s dive into the betting data, trends, odds and insights for this season opening games from the 12th Man.

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New England Patriots vs. Seattle Seahawks Game Betting Analysis

It’s difficult to go against the Seahawks here, on a 10-game outright winning streak along with wins in a remarkable 14 straight games as the favorite. The moneyline is too expensive to take, however, so do we then test the spread? The data points to Seattle covering, as the Patriots are 1-4-1 ATS in their last six meetings with the Seahawks.

Also, New England has failed to cover the spread in four of five season opening games which does no favors in the loudest NFL stadium on ‘Super Bowl Celebration’ night. Finally, New England has failed to cover the spread in six straight games when facing the NFC West as an underdog. So there’s a lot of data suggesting Seattle wins and covers – but what about the total? The Over has hit in five of six meetings, the Under being the Super Bowl last season. Seattle also went 7-3 O/U at home last season, but New England going Under in seven of eight season opening games leads us back to the ATS as the better play.

New England Patriots vs. Seattle Seahawks Game Best Bet, Pick & Prediction

Best Bet: Seahawks -3 (-118) at DraftKings
Score Prediction: Seahawks 24, Patriots 20

New England Patriots vs. Seattle Seahawks Game Odds

New England Patriots vs. Seattle Seahawks Game Information

  • Date: Wednesday, September 9, 2026
  • Time: 8:20 p.m. ET
  • Network: NBC
  • Location: Seattle, Washington
  • Venue: Lumen Field – 51.2 ppg; 7-3 O/U

New England Patriots vs. Seattle Seahawks Game Betting Resources

New England Patriots vs. Seattle Seahawks Game Key Players

New England

  • Drake Maye, QB – Last Game: n/a
  • Christian Gonzalez, CB – Last Game: n/a
  • A.J. Brown, WR – Last Game: n/a

Seattle

  • Sam Darnold, QB – Last Game: n/a
  • Jaxon Smith-Njigba, WR – Last Game: n/a
  • Jadarian Price, RB – Last Game: n/a

Photo Credit: REUTERS

About the Author
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Thom Cunningham is the Lineups.com News Editor and has been involved with sports media for almost two decades at Spectrum, VegasInsider.com, Oddschecker, VSiN and much more as a content producer - focused on the betting and gaming space over the last decade tracking insights, data analytics and covering various markets from the NFL to the Oscars. 

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