The NFL season kicks off on a Wednesday this season, with a rematch from the Super Bowl as the New England Patriots will face the Seattle Seahawks. Let’s dive into the betting data, trends, odds and insights for this season opening games from the 12th Man.
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New England Patriots vs. Seattle Seahawks Game Betting Analysis
It’s difficult to go against the Seahawks here, on a 10-game outright winning streak along with wins in a remarkable 14 straight games as the favorite. The moneyline is too expensive to take, however, so do we then test the spread? The data points to Seattle covering, as the Patriots are 1-4-1 ATS in their last six meetings with the Seahawks.
Also, New England has failed to cover the spread in four of five season opening games which does no favors in the loudest NFL stadium on ‘Super Bowl Celebration’ night. Finally, New England has failed to cover the spread in six straight games when facing the NFC West as an underdog. So there’s a lot of data suggesting Seattle wins and covers – but what about the total? The Over has hit in five of six meetings, the Under being the Super Bowl last season. Seattle also went 7-3 O/U at home last season, but New England going Under in seven of eight season opening games leads us back to the ATS as the better play.
New England Patriots vs. Seattle Seahawks Game Best Bet, Pick & Prediction
Best Bet: Seahawks -3 (-118) at DraftKings
Score Prediction: Seahawks 24, Patriots 20
New England Patriots vs. Seattle Seahawks Game Odds
New England Patriots vs. Seattle Seahawks Game Information
- Date: Wednesday, September 9, 2026
- Time: 8:20 p.m. ET
- Network: NBC
- Location: Seattle, Washington
- Venue: Lumen Field – 51.2 ppg; 7-3 O/U
New England Patriots vs. Seattle Seahawks Game Betting Resources
New England Patriots vs. Seattle Seahawks Game Key Players
New England
- Drake Maye, QB – Last Game: n/a
- Christian Gonzalez, CB – Last Game: n/a
- A.J. Brown, WR – Last Game: n/a
Seattle
- Sam Darnold, QB – Last Game: n/a
- Jaxon Smith-Njigba, WR – Last Game: n/a
- Jadarian Price, RB – Last Game: n/a
Photo Credit: REUTERS