San Francisco 49ers Odds 2026: Latest Super Bowl 60 Odds
After nearly upending Patrick Mahomes and Co. in Super Bowl 58, San Francisco massively underwhelmed the betting market’s expectations last season. However, the 49ers’ Super Bowl odds of indicate that a potential bounce-back campaign is in store.
Robert Saleh returning as their defensive coordinator should serve as a boost, excelling in this position before unimpressing as the Jets’ head coach. They lost integral pieces on both sides of the ball, including Deebo Samuel, Dre Greenlaw, and Talanoa Hufanga, while failing to address their offensive line. Nevertheless, their schedule sets up well, improving from the fifth-hardest in 2024-25 to the easiest across the NFL.
In particular, San Francisco’s net rest advantage rose from -22 to +9 — a full month of added rest against opponents. It will face no opponents coming off a bye, and eight of its final 10 games are against teams coming off road affairs.
Check out the rest of the 49ers’ futures markets below.
San Francisco 49ers 2025-26 Super Bowl Odds & Futures
