Buffalo Bills Schedule 2022 Buffalo Bills Schedule
13-3, 1st AFC East
Final
The Bills kick off their 2022 season with a highly anticipated matchup in Los Angeles against the defending Super Bowl Champion Rams. Things don’t get any easier for Josh Allen and company from there as they play the #1 seed Titans (home), upstart Dolphins (road), and rejuvenated Ravens (road) in their next four games. Buffalo also has a massive rematch of their AFC Divisional loss to the Chiefs in Week 6 and an epic primetime showdown against the Aaron Rodgers’ Packers in Week 8 following their Week 7 bye. The Bills are featured on Thanksgiving this year as they travel to Detroit on the holiday. They also have several winnable games down the stretch against the Patriots (twice), Jets and Dolphins at home, and Bears on the road in their final six games. The one difficult game in that stretch comes against Cincinnati on the road as they meet the defending AFC Champion in a measuring stick game in Week 17.
| WK | Date | Time | Opponent | Spread | Moneyline | Total | Score | Record | Matchup |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 9/9/22 | 12:20 am | at  LAR Rams Los Angeles Rams | BUF -2.5 | BUF -130/LAR +110 | O/U 52.0 | 31-10 | 1 - 0 | Bills at Rams |
| 2 | 9/19/22 | 11:15 pm | vs  TEN Titans Tennessee Titans | BUF -10.0 | TEN +350/BUF -435 | O/U 47.5 | 41-7 | 2 - 0 | Bills vs Titans |
| 3 | 9/25/22 | 5:00 pm | at  MIA Dolphins Miami Dolphins | BUF -4.0 | BUF -195/MIA +165 | O/U 54.5 | 19-21 | 2 - 1 | Bills at Dolphins |
| 4 | 10/2/22 | 5:00 pm | at  BAL Ravens Baltimore Ravens | BUF -3.5 | BUF -170/BAL +145 | O/U 50.5 | 23-20 | 3 - 1 | Bills at Ravens |
| 5 | 10/9/22 | 5:00 pm | vs  PIT Steelers Pittsburgh Steelers | BUF -14.5 | PIT +550/BUF -750 | O/U 44.5 | 38-3 | 4 - 1 | Bills vs Steelers |
| 6 | 10/16/22 | 8:25 pm | at  KC Chiefs Kansas City Chiefs | BUF -2.5 | BUF -150/KC +130 | O/U 54.0 | 24-20 | 5 - 1 | Bills at Chiefs |
| 7 | BYE WEEK | ||||||||
| 8 | 10/31/22 | 12:20 am | vs  GB Packers Green Bay Packers | BUF -10.5 | GB +350/BUF -435 | O/U 47.0 | 27-17 | 6 - 1 | Bills vs Packers |
| 9 | 11/6/22 | 6:00 pm | at  NYJ Jets New York Jets | BUF -10.5 | BUF -520/NYJ +410 | O/U 46.0 | 17-20 | 6 - 2 | Bills at Jets |
| 10 | 11/13/22 | 6:00 pm | vs  MIN Vikings Minnesota Vikings | BUF -6.5 | MIN +245/BUF -295 | O/U 47.5 | 30-33 | 6 - 3 | Bills vs Vikings |
| 11 | 11/20/22 | 6:00 pm | vs  CLE Browns Cleveland Browns | BUF -7.5 | CLE +300/BUF -365 | O/U 50.5 | 31-23 | 7 - 3 | Bills vs Browns |
| 12 | 11/24/22 | 5:30 pm | at  DET Lions Detroit Lions | BUF -9.5 | BUF -410/DET +330 | O/U 54.5 | 28-25 | 8 - 3 | Bills at Lions |
| 13 | 12/2/22 | 1:15 am | at  NE Patriots New England Patriots | BUF -3.5 | BUF -200/NE +170 | O/U 44.0 | 24-10 | 9 - 3 | Bills at Patriots |
| 14 | 12/11/22 | 6:00 pm | vs NYJ Jets New York Jets | BUF -9.5 | NYJ +370/BUF -460 | O/U 44.0 | 20-12 | 10 - 3 | Bills vs Jets |
| 15 | 12/18/22 | 1:15 am | vs MIA Dolphins Miami Dolphins | BUF -7.0 | MIA +290/BUF -350 | O/U 44.5 | 32-29 | 11 - 3 | Bills vs Dolphins |
| 16 | 12/24/22 | 6:00 pm | at  CHI Bears Chicago Bears | BUF -8.0 | BUF -410/CHI +330 | O/U 40.5 | 35-13 | 12 - 3 | Bills at Bears |
| 17 | 1/3/23 | 1:30 am | at  CIN Bengals Cincinnati Bengals | BUF -2.5 | BUF -145/CIN +125 | O/U 51.0 | - | 12 - 3 | Bills at Bengals |
| 18 | 1/8/23 | 6:00 pm | vs NE Patriots New England Patriots | BUF -7.0 | NE +255/BUF -305 | O/U 42.0 | 35-23 | 13 - 3 | Bills vs Patriots |
| POSTSEASON | |||||||||
| 1 | 1/15/23 | 6:00 pm | vs MIA Dolphins Miami Dolphins | BUF -14.0 | MIA +700/BUF -1050 | O/U 44.0 | 34-31 | 1 - 0 | Bills vs Dolphins |
| 2 | 1/22/23 | 8:00 pm | vs CIN Bengals Cincinnati Bengals | BUF -5.5 | CIN +200/BUF -240 | O/U 48.5 | 10-27 | 1 - 1 | Bills vs Bengals |
