Buffalo Bills Schedule 2022 Buffalo Bills Schedule
2-0, 2nd AFC East
@ MIA
5:00 pm GMT , 9/25
The Bills kick off their 2022 season with a highly anticipated matchup in Los Angeles against the defending Super Bowl Champion Rams. Things don’t get any easier for Josh Allen and company from there as they play the #1 seed Titans (home), upstart Dolphins (road), and rejuvenated Ravens (road) in their next four games. Buffalo also has a massive rematch of their AFC Divisional loss to the Chiefs in Week 6 and an epic primetime showdown against the Aaron Rodgers’ Packers in Week 8 following their Week 7 bye. The Bills are featured on Thanksgiving this year as they travel to Detroit on the holiday. They also have several winnable games down the stretch against the Patriots (twice), Jets and Dolphins at home, and Bears on the road in their final six games. The one difficult game in that stretch comes against Cincinnati on the road as they meet the defending AFC Champion in a measuring stick game in Week 17.
| WK | Date | Time | Opponent | Stadium | Score | Record | Matchup |
|---|---|---|---|---|---|---|---|
| 1 | 9/9/22 | 12:20 am | at  LAR Rams Los Angeles Rams | SoFi Stadium | 31-10 | 1 - 0 | Bills at Rams |
| 2 | 9/19/22 | 11:15 pm | vs  TEN Titans Tennessee Titans | Highmark Stadium | 41-7 | 2 - 0 | Bills vs Titans |
