Buffalo Bills Schedule 2021 Buffalo Bills Schedule

0-0, T-1st AFC East

vs PIT

5:00 pm GMT , 9/12

The Bills open up the season with a couple of divisional games, and in the AFC East, that is not a bad thing. While the Jets and Miami are set to improve a tad, the Bills are near favorites to take the division for the first time in years. The Bills will welcome the Los Angeles Rams in Week 3, which is an advantage for them getting them to travel across the country. However they will go out to Las Vegas the week after, and then play Tennessee on the road. A big Thursday Night game is Kansas City traveling to Buffalo. A couple of divisional games will follow going on the road to face the Jets and then back at home for New England. The Bills have another tough game, but once again they will be at home to face the Seahawks. Before the Bye Week, the Bills will go to Arizona. After the Bye Week, the Bills take on some extremely tough defenses. They will face the Chargers at home, before going the on the road to face the San Francisco 49ers. The stretch of facing the Steelers, Broncos, and Patriots is tough before a home game to finish the 2020 season against Miami.

Date Time Opponent Stadium Record Opponent Depth Chart Bills Depth Chart Matchup
9/12/21 5:00 pm vs Pittsburgh Steelers Pittsburgh Steelers Bills Stadium 0 - 0 Pittsburgh Steelers Steelers Buffalo Bills Bills Buffalo Bills Bills vs Pittsburgh Steelers Steelers
9/19/21 5:00 pm at Miami Dolphins Miami Dolphins Hard Rock Stadium 0 - 0 Miami Dolphins Dolphins Buffalo Bills Bills
9/26/21 5:00 pm vs Washington Football Team Washington Football Team Bills Stadium 0 - 0 Washington Football Team Washington Buffalo Bills Bills
10/3/21 5:00 pm vs Houston Texans Houston Texans Bills Stadium 0 - 0 Houston Texans Texans Buffalo Bills Bills
10/11/21 12:20 am at Kansas City Chiefs Kansas City Chiefs Arrowhead Stadium 0 - 0 Kansas City Chiefs Chiefs Buffalo Bills Bills
10/19/21 12:15 am at Tennessee Titans Tennessee Titans Nissan Stadium 0 - 0 Tennessee Titans Titans Buffalo Bills Bills
10/31/21 5:00 pm vs Miami Dolphins Miami Dolphins Bills Stadium 0 - 0 Miami Dolphins Dolphins Buffalo Bills Bills
11/7/21 6:00 pm at Jacksonville Jaguars Jacksonville Jaguars TIAA Bank Field 0 - 0 Jacksonville Jaguars Jaguars Buffalo Bills Bills
11/14/21 6:00 pm at New York Jets New York Jets MetLife Stadium 0 - 0 New York Jets Jets Buffalo Bills Bills
11/21/21 6:00 pm vs Indianapolis Colts Indianapolis Colts Bills Stadium 0 - 0 Indianapolis Colts Colts Buffalo Bills Bills
11/26/21 1:20 am at New Orleans Saints New Orleans Saints Mercedes-Benz Superdome 0 - 0 New Orleans Saints Saints Buffalo Bills Bills
12/7/21 1:15 am vs New England Patriots New England Patriots Bills Stadium 0 - 0 New England Patriots Patriots Buffalo Bills Bills
12/12/21 9:25 pm at Tampa Bay Buccaneers Tampa Bay Buccaneers Raymond James Stadium 0 - 0 Tampa Bay Buccaneers Buccaneers Buffalo Bills Bills
12/19/21 6:00 am vs Carolina Panthers Carolina Panthers Bills Stadium 0 - 0 Carolina Panthers Panthers Buffalo Bills Bills
12/26/21 6:00 pm at New England Patriots New England Patriots Gillette Stadium 0 - 0 New England Patriots Patriots Buffalo Bills Bills
1/2/22 6:00 pm vs Atlanta Falcons Atlanta Falcons Bills Stadium 0 - 0 Atlanta Falcons Falcons Buffalo Bills Bills
1/9/22 6:00 pm vs New York Jets New York Jets Bills Stadium 0 - 0 New York Jets Jets Buffalo Bills Bills