Buffalo Bills Schedule 2022 Buffalo Bills Schedule

13-3, 1st AFC East

CIN 27 @ BUF 10

Final

2/12, 11:30p
2/12, 11:30p
KC
Chiefs
PHI
Eagles

The Bills kick off their 2022 season with a highly anticipated matchup in Los Angeles against the defending Super Bowl Champion Rams. Things don’t get any easier for Josh Allen and company from there as they play the #1 seed Titans (home), upstart Dolphins (road), and rejuvenated Ravens (road) in their next four games. Buffalo also has a massive rematch of their AFC Divisional loss to the Chiefs in Week 6 and an epic primetime showdown against the Aaron Rodgers’ Packers in Week 8 following their Week 7 bye. The Bills are featured on Thanksgiving this year as they travel to Detroit on the holiday. They also have several winnable games down the stretch against the Patriots (twice), Jets and Dolphins at home, and Bears on the road in their final six games. The one difficult game in that stretch comes against Cincinnati on the road as they meet the defending AFC Champion in a measuring stick game in Week 17.

WK Date Time Opponent Spread Moneyline Total Score Record Matchup
1 9/9/22 12:20 am at Los Angeles Rams LAR Rams Los Angeles Rams BUF -2.5 BUF -130/LAR +110 O/U 52.0 31-10 1 - 0 Bills at Rams
2 9/19/22 11:15 pm vs Tennessee Titans TEN Titans Tennessee Titans BUF -10.0 TEN +350/BUF -435 O/U 47.5 41-7 2 - 0 Bills vs Titans
3 9/25/22 5:00 pm at Miami Dolphins MIA Dolphins Miami Dolphins BUF -4.0 BUF -195/MIA +165 O/U 54.5 19-21 2 - 1 Bills at Dolphins
4 10/2/22 5:00 pm at Baltimore Ravens BAL Ravens Baltimore Ravens BUF -3.5 BUF -170/BAL +145 O/U 50.5 23-20 3 - 1 Bills at Ravens
5 10/9/22 5:00 pm vs Pittsburgh Steelers PIT Steelers Pittsburgh Steelers BUF -14.5 PIT +550/BUF -750 O/U 44.5 38-3 4 - 1 Bills vs Steelers
6 10/16/22 8:25 pm at Kansas City Chiefs KC Chiefs Kansas City Chiefs BUF -2.5 BUF -150/KC +130 O/U 54.0 24-20 5 - 1 Bills at Chiefs
7 BYE WEEK
8 10/31/22 12:20 am vs Green Bay Packers GB Packers Green Bay Packers BUF -10.5 GB +350/BUF -435 O/U 47.0 27-17 6 - 1 Bills vs Packers
9 11/6/22 6:00 pm at New York Jets NYJ Jets New York Jets BUF -10.5 BUF -520/NYJ +410 O/U 46.0 17-20 6 - 2 Bills at Jets
10 11/13/22 6:00 pm vs Minnesota Vikings MIN Vikings Minnesota Vikings BUF -6.5 MIN +245/BUF -295 O/U 47.5 30-33 6 - 3 Bills vs Vikings
11 11/20/22 6:00 pm vs Cleveland Browns CLE Browns Cleveland Browns BUF -7.5 CLE +300/BUF -365 O/U 50.5 31-23 7 - 3 Bills vs Browns
12 11/24/22 5:30 pm at Detroit Lions DET Lions Detroit Lions BUF -9.5 BUF -410/DET +330 O/U 54.5 28-25 8 - 3 Bills at Lions
13 12/2/22 1:15 am at New England Patriots NE Patriots New England Patriots BUF -3.5 BUF -200/NE +170 O/U 44.0 24-10 9 - 3 Bills at Patriots
14 12/11/22 6:00 pm vs New York Jets NYJ Jets New York Jets BUF -9.5 NYJ +370/BUF -460 O/U 44.0 20-12 10 - 3 Bills vs Jets
15 12/18/22 1:15 am vs Miami Dolphins MIA Dolphins Miami Dolphins BUF -7.0 MIA +290/BUF -350 O/U 44.5 32-29 11 - 3 Bills vs Dolphins
16 12/24/22 6:00 pm at Chicago Bears CHI Bears Chicago Bears BUF -8.0 BUF -410/CHI +330 O/U 40.5 35-13 12 - 3 Bills at Bears
17 1/3/23 1:30 am at Cincinnati Bengals CIN Bengals Cincinnati Bengals BUF -2.5 BUF -145/CIN +125 O/U 51.0 - 12 - 3 Bills at Bengals
18 1/8/23 6:00 pm vs New England Patriots NE Patriots New England Patriots BUF -7.0 NE +255/BUF -305 O/U 42.0 35-23 13 - 3 Bills vs Patriots
POSTSEASON
1 1/15/23 6:00 pm vs Miami Dolphins MIA Dolphins Miami Dolphins BUF -14.0 MIA +700/BUF -1050 O/U 44.0 34-31 1 - 0 Bills vs Dolphins
2 1/22/23 8:00 pm vs Cincinnati Bengals CIN Bengals Cincinnati Bengals BUF -5.5 CIN +200/BUF -240 O/U 48.5 10-27 1 - 1 Bills vs Bengals