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Jacksonville State-Kennesaw State Picks, Predictions & Odds: College Football Week 6

Picks, predictions and odds for Jacksonville State vs. Kennesaw State in Week 6 college football, plus the key stat matchup that decides it.
Deondre Johnson
Thom Cunningham Avatar
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Best Bet: U49.5 (-110) at DraftKings

Score Prediction: Jacksonville State 28, Kennesaw State 21

The Pick: Jacksonville State 28, Kennesaw State 21

We’ll take the Under based on Kennesaw State’s betting data.

Game Betting Analysis

The Under seems to be where we are heading here, with Kennesaw State hitting the Under in both home games this season. The Owls have also hit the Under in six straight games, dating back to last season. The ATS market also has a bit of uncertainty, as Kennesaw State holds a 3-1 ATS mark this season but more data points to Jacksonville State. The Gamecocks have seen the favorites cover seven straight spreads, while also winning nine straight games outright in the month of October. With the ATS market offering various data points, we’ll simply ride with the Owls current Under run.

Jacksonville State-Kennesaw State Odds (Spread, Moneyline, Over/Under)

Deciding Factor: Kennesaw State’s Run Game vs. Jacksonville State’s Run Defense

Kennesaw State’s only functional path to an upset is on the ground, and it happens to run into Jacksonville State’s one real soft spot. The Gamecocks have allowed 854 rushing yards through five games (170.8 per game, 4.3 yards per carry, 57th nationally), while Kennesaw State’s ground game is averaging 167.0 yards per game at a healthy 5.2 yards per carry behind Boogie Woods II, who ran for 101 yards and two touchdowns against Arkansas State last time out. If Woods and the Owls’ offensive line can control the clock and stay ahead of schedule the way they did in that near-upset, Kennesaw State keeps this game within reach of the 3-to-3.5-point number.

The problem is what happens the moment Kennesaw State has to throw. Jacksonville State’s pass defense is a legitimate top-20 unit — 150.8 yards allowed per game (17th nationally), just a 65.9% completion rate allowed and only 5 touchdown passes surrendered all season — against a Kennesaw State passing attack that ranks 97th in the country at 201.0 yards per game. Quarterback Rickie Collins has already been exposed there, managing just 129 yards through the air in the loss to Arkansas State, and if the Owls fall behind or stall on early downs, that’s exactly the matchup they’d be forced into. Whether Kennesaw State can win on the ground long enough to never need Collins to beat this secondary is the actual swing point of Wednesday’s game.

Game Information

  • Date: Wednesday, October 7, 2026
  • Kickoff: 7:00 p.m. ET
  • Network: CBSSN, Paramount+
  • Venue: Walens Family Field at Fifth Thir dStadium – 47.5 ppg; 0-2 O/U
  • Conference: Conference-USA

Best Bets for College Football Week 6

  • Under 49.5 (-110)

Key Players

Jacksonville State

  • QB, Caden Creel — Last Game: 19/27, 241 yards, TD, 2 INT; 12 carries, 119 yards, TD
  • RB, Lucas Farrington — Last Game: 12 carries, 94 yards

Kennesaw State

  • QB, Rickie Collins— Last Game: 17/24, 129 yards; 9 carries, 52 yards
  • RB, Boogie Woods III — Last Game: 19 carries, 101 yards, 2 TD

Photo Credit: REUTERS

About the Author
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Thom Cunningham is the Lineups.com News Editor and has been involved with sports media for almost two decades at Spectrum, VegasInsider.com, Oddschecker, VSiN and much more as a content producer - focused on the betting and gaming space over the last decade tracking insights, data analytics and covering various markets from the NFL to the Oscars. 

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