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MLB Home Run Predictions, Picks, Props, Odds for Friday, June 26, 2026

Check out the best MLB home run picks and predictions for games on Friday, June 26 with odds and insights provided by Lineups.com.
Caglianone
Frank Ammirante Avatar
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It was a profitable night on Thursday, as Joc Pederson hit a home run, making up for a loss on Bryson Stott. The Diamondbacks vs Cardinals was rained out, so my Lars Nootbaar bet was void.

Today, we’re going with Junior Caminero, Riley Greene, and Jac Caglianone. Each of these hitters is in a good spot. Let’s ride with them to build off Thursday’s win.

Remember to be sure to check out our daily MLB betting trends page.

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2026 MLB HR Props Record: 52-204 (+0.54 units) 

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Home Run Prop Predictions & Odds: MLB HR Best Bets for Friday, June 26

Junior Caminero Home Run Odds

Junior Caminero is slashing .285/.377/.519 with 19 home runs in 342 plate appearances. He’s increased his walk rate from 6.3% to 13.2% and trimmed his strikeout rate from 19.1% to 17.8%. He’s also maintained a respectable 12.7% barrel rate. Needless to say, it’s been a strong follow-up to his 45-homer season from last year.

Caminero is coming off a monster game against the Royals, where he homered three times. That’s now four home runs in his last three games. For power hitters like Caminero, home runs often come in bunches. This looks like one of those times, so we have to hop on board this freight train.

It’s a great matchup against Diamondbacks’ righty Zac Gallen, who has a 5.70 xERA and a 1.47 HR/9 this season. Gallen has allowed six home runs in his last five starts.

We’re getting this prop at longer than +300 odds, making it a nice value on one of the best hitters in baseball. Risk 0.1 units.

Riley Greene Home Run Odds

Riley Greene hasn’t been nearly as good as last year in terms of power, where he hit 36 home runs, as he’s only at nine so far. But he’s still hitting the ball hard (12.9% barrel rate), so it’s only a matter of time before he gets going. We saw him homer as recently as June 22nd.

I like him to go yard once again here, as it’s a good matchup vs. Astros’ right-hander Spencer Arrighetti. This a pitcher who is ripe for regression, as his 4.57 xERA is much higher than his 3.13 ERA.

More importantly, Greene has some of the craziest batter-vs-pitcher data against Arrighetti that you’ll ever see. In five career plate appearances, Greene has three home runs and a 1.824 expected slugging percentage vs. Arrighetti.

Simply put, I can’t pass up those numbers. We’ll take a shot on Greene to hit No. 10 tonight. Risk 0.1 units.

Jac Caglianone Home Run Odds

Jac Caglianone is showing everyone why he was such a touted prospect coming out of college. June has been a monster month for the Royals’ slugger, as he’s slashing .337/.415/.699 with nine home runs in 94 plate appearances.

This includes six home runs in his last seven games. That’s the kind of hot streak that we don’t want to continue to miss out on, especially when we’re getting +400 odds on him to go yard.

The White Sox are going with Davis Sandlin for this game. This is a pitcher with a 2.70 HR/9 on the season. He’s allowed four homers in his three starts.

With how hot Caglianone has been at the plate, this is the ideal spot to ride with him. Risk 0.1 units.

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About the Author
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Frank Ammirante

Senior Staff Writer

Frank Ammirante has spent the last 5+ years covering sports betting, fantasy sports, and the wider iGaming industry, with a focus on MLB and NFL betting alongside fantasy baseball and football strategy, as well as basketball, hockey, and soccer. His work has appeared on outlets like The Game Day, RotoBaller, FantasyPros, Deadspin, and Pro Football Network, and more, where he's covered everything from player props and betting futures to online casino and sweepstakes casino reviews, prediction markets, and industry news. He also brings hands-on editorial experience as a content editor elsewhere in the industry. Frank started out in the fantasy sports space, and today he's a member of the Fantasy Sports Writers Association who competes in some of the industry's toughest expert fantasy leagues, including Tout Wars, Scott Fish Bowl, and The Great Fantasy Baseball Invitational. He's an annual competitor in Tout Wars specifically, and his fantasy baseball rankings have been featured in Fantasy Index's fantasy baseball magazine. Off the clock, he's a die-hard Toronto Blue Jays and Washington Commanders fan who still isn't quite over the Blue Jays' World Series loss to the Dodgers, which he's called "one of the biggest collapses in sports history."

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