2 49ers-Eagles Anytime Touchdown Scorer Picks: How To Bet NFL Wild Card ATD (Sunday, January 11)

It’s Wild Card Sunday of the NFL season, and we’ve got a pair of 49ers vs. Eagles anytime touchdown predictions for Sunday’s action.

The rematch of the 2022 NFC Championship game takes place at Lincoln Financial Field as the defending champion Eagles (11-6) square off with the 49ers (12-5).

In that matchup, Philadelphia routed San Francisco, 31-7 as the 49ers played most of that game basically with no passing game as Brock Purdy left due to injury.

The Niners had a shot to finish as the top NFC seed but lost in the season finale at home to eventual #1 seed Seattle. Philadelphia has won five consecutive home playoff games dating back to 2022 with four victories by double-digits.

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49ers vs. Eagles Anytime Touchdown Scorer Picks (Sunday, January 11)

In six of the final nine games of the season, Philadelphia was held to 2 TDs or less. The Eagles failed to score more than 2 TDs in three of the last four home contests, but that includes the Week 18 loss to Washington without Hurts in the lineup.

The 49ers have scored at least 4 TDs in three of their last four road games and put up 3 TDs in the other attempt in this stretch. Purdy threw 9 TD passes in the past three away performances, while backup QB Mac Jones posted a pair of TDs in a Week 9 win against the Giants.

The three biggest favorites to reach the end zone at DraftKings are led by 49ers RB Christian McCaffrey (-135), Eagles RB Saquon Barkley (-130), and Eagles QB Jalen Hurts (+105). Note: Prices are accurate as of publishing time. 

Barkley experienced a TD drop from last season, when he reached the end zone 15 times. In 2025, the former Penn State star rushed for 7 TDs and posted a pair of receiving TDs. McCaffrey scored a total of 17 TDs (10 rushing, 7 receiving), while finding the end zone in seven of nine road games.

49ers-Eagles Anytime Touchdown Picks: Dallas Goedert

San Francisco has yielded 10 TDs to opposing tight ends, the fourth-most in the NFL. Goedert led the Eagles with 11 TD receptions, including 4 TDs in the final three games. At home, the 2018 second round pick recorded 6 TDs, although he had a pair of multi-TD performances against the Giants and Raiders.

Hurts has thrown at least 2 TD passes in six of eight games at Lincoln Financial Field, so the opportunities will be there for Goedert to reach the end zone.

49ers-Eagles Anytime Touchdown Picks: Jauan Jennings

Jennings was held to 1 TD in his first six games, but the 49ers WR rebounded with 8 TDs in the final nine outings. The former Tennessee Volunteer has reached the end zone in three of the past four road contests but faces a Philadelphia defense that has given up 6 TDs to opposing wide receivers.

Best of luck with your NFL touchdown bets for Sunday’s Wild Card action!

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Kevin Rogers brings over 15 years of experience in the sports betting industry to Lineups.com. He spent more than a decade at VegasInsider as both a handicapper and writer, covering the NFL, NBA, MLB, NHL, college football, and college basketball. Kevin has also contributed college hoops and MLB analysis for the Action Network, and he continues to handicap the NFL professionally. His work blends deep statistical insight with a sharp bettor’s perspective, helping readers make more informed wagering decisions every season.

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