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Missouri-Marquette Picks, Predictions & Odds: College Basketball

Check out the Missouri vs. Marquette college basketball game preview with picks, predictions and odds provided by Lineups.com.
Adrien Stevens
Thom Cunningham Avatar
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Best Bet: MARQ ML (-105) at Fanatics

Best Bet: U154 (-111) at Fanatics

Score Prediction: Marquette 77, Missouri 76

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The Pick: Marquette 77, Missouri 76

We’ll take Marquette’s moneyline based on Missouri’s non-conference struggles, while the Under is in play based on Marquette’s data against SEC schools.


Game Betting Analysis

There’s a lot going against Marquette’s spread here, failing to cover nine of 11 non-conference games. The Golden Eagles have dropped the spread in three straight games on a neutral court, have failed to cover the spread in 11 of 14 games as the favorites and 8-15 ATS when playing off three days of rest. With that said, Mizzou has lost outright in nine straight non-conference games played on a neutral court, failing to cover four straight games on a neutral court. It’s hard to trust either team in the ATS market, so what about the total? Marquette has hit 150 total points or less in five straight games against the SEC. There’s not a lot of conviction here, but the most trust is in the Under and Marquette’s moneyline.


Missouri-Marquette Odds (Spread, Moneyline, Over/Under)

Deciding Factor: Marquette’s Suffocating Defense vs. Missouri’s Leaky Perimeter D

Marquette brings the better defensive résumé into Sunday’s Chicago Legends Classic matchup, even sitting at 2-1 after a 14-point road loss at then-No. 20 Michigan. Shaka Smart’s rebuilt roster opened by holding Mercyhurst to 43 points in a 78-43 win and then throttled Detroit Mercy 93-32, limiting the Titans to under 45 points for the second straight game, with Josh Clark (18 points, a career high), Royce Parham (16 points, 7 rebounds) and Sananda Fru (12 points, 12 rebounds) all producing. Even in the loss at Michigan, Marquette hung around into the second half before the Wolverines’ size took over, with Colin Porter (21 points) and Adrien Stevens (16 points) doing enough offensively that the defense — not the offense — was the bigger issue in that game. A group capable of holding two opponents to a combined 75 points this season is exactly the kind of test that can bother a young, fast-paced Missouri attack that hasn’t had to execute in the half court yet.

Missouri, meanwhile, has been must-see on offense but leaky enough on defense to lose a game it probably should have won. Freshman Jason Crowe Jr. has been the headline, scoring 23 in the season-opening 111-50 rout of Cleveland State and then setting the program’s single-game freshman scoring record with 34 points (11-of-16 shooting, four 3-pointers) in a 96-58 blowout of SIU Edwardsville, but in between, Dennis Gates’s Tigers lost 90-84 to crosstown Saint Louis despite 26 points and 9 rebounds from Bryson Tiller and 21 from Mark Mitchell, largely because they let the Billikens shoot 56% from three (14-of-25) while making just 33.3% of their own. Mitchell, Missouri’s most experienced frontcourt piece, also left the SIU Edwardsville game early with a facial injury and didn’t return, clouding his availability for Sunday. If Marquette’s defense forces Missouri into the same kind of perimeter-shooting track meet that Saint Louis won, and Mitchell is limited or out, the Golden Eagles’ discipline gives them a real path to slowing down the nation’s newest freshman scoring record-holder.

Game Information

  • Date: Sunday, November 15, 2026
  • Kickoff: 2:00 p.m. (ET)
  • Network: Peacock
  • Location: Chicago, Illinois
  • Venue: United Center – 155 ppg

College Basketball Game Trends & Odds

Key Players

Missouri Tigers

  • Jason Crowe Jr. — Last Game: 34 points
  • Toni Bryant — Last Game: 18 points, 7 rebounds

Marquette Golden Eagles

  • Adrien Stevens — Last Game: 16 points
  • Royce Parham — Last Game: 8 points, 6 rebounds

Photo Credit: REUTERS

About the Author
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Thom Cunningham is the Lineups.com News Editor. He has worked in sports media for almost two decades as a content producer, including roles at Spectrum, VegasInsider.com, Oddschecker and VSiN. Over the last decade he has focused on the sports betting and gaming space, tracking insights and data analytics and covering markets from the NFL to the Oscars. His MLB picks are also graded by DailyOverlay, which ranks industry experts.

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