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Yankees vs. Rays Game 2 Picks, Predictions & Odds: MLB Playoffs Divisional Series

Check out the MLB ALDS Game 2 preview for the Yankees vs. Rays with picks, predictions and odds provided by Lineups.com.
Jonathan Aranda
Thom Cunningham Avatar
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Best Bet: NYY -1.5 (+150) at Hard Rock Bet

Best Bet: O6.5 (-115)

Score Prediction: Yankees 5, Rays 2

The Pick: Yankees 5, Rays 2

We’ll take the Yankees to cover the run line based on head-to-head data along with overall value.

Game Betting Analysis

The pitcher matchup alone points to the Under, but let’s see what the data says. Despite the arms, and Game 1, the Over still seems to be favored with it hitting in four of six meetings, along with 12 of 13 games for the Yankees when facing the AL as favorites. The Yankees have covered the run line in three straight meetings, along with five of the last six – three of those five as the favorites. New York has also covered the run line in six straight games when playing as the favorite and coming off a loss, so there is value to test if the Over worries you as it does us.

MLB Game Trends & Betting Data

Yankees vs. Rays Odds (Spread, Moneyline, Over/Under)

Deciding Factor: Cam Schlittler’s Road Mastery vs. Freddy Peralta’s Tropicana Magic

This one hinges on which ace’s recent form is more real. Schlittler enters as the likely AL Cy Young winner and has been nearly untouchable away from Yankee Stadium — 8-2, 1.16 ERA across 17 road starts, leading all of MLB in road strikeouts (129) and opponent batting average (.153). If that pitcher shows up, a Rays lineup that’s been efficient rather than explosive all year could be in for a long night. But Peralta has been every bit as locked in lately: he was September’s AL Pitcher of the Month at 5-0 with a 0.79 ERA over his last six starts, and he’s been even better at home, posting a 1.69 ERA in his last four starts at Tropicana Field. Against the Rays specifically, Schlittler’s numbers dip to a 2.81 ERA across three starts this season, so this isn’t a clean mismatch in his favor.

The bigger question may be whether New York’s offense can solve either pitcher at all. The Yankees hit just .235 as a team this season, relying on power (223 home runs) over consistent contact, and they’ve now been stifled in elite pitching performances to open this series. Tampa Bay, by contrast, built its season around exactly this kind of low-event, one-run game — the Rays were a model of execution in close games. If Peralta turns in anything close to his recent form, a Yankees lineup already searching for answers may not have enough margin for error, even with one of the best pitchers in the sport on their side.

Game Information

  • Date: Monday, October 5, 2026
  • Kickoff: 8:00 p.m. ET
  • Network: TBS, truTV
  • Venue: Tropicana Field – 8.5 runs per game; 37-43-4
  • Series Score: Rays 1-0

MLB Playoffs Betting Central

Key Players

New York Yankees

  • Cody Bellinger — Last Game: 0/4
  • Ben Rice — Last Game: 0/3, BB

Tampa Bay Rays

  • Junior Caminero — Last Game: 0/2, 2 BB
  • Liam Hicks — Last Game: 1/3, 2B, BB

Photo Credit: REUTERS

About the Author
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Thom Cunningham is the Lineups.com News Editor and has been involved with sports media for almost two decades at Spectrum, VegasInsider.com, Oddschecker, VSiN and much more as a content producer - focused on the betting and gaming space over the last decade tracking insights, data analytics and covering various markets from the NFL to the Oscars. 

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