Vegas Golden Knights vs. Colorado Avalanche Game 1 Preview, Picks & Odds for Wednesday, May 20, 2026

Game 1 of the Western Conference Finals is finally here with the Vegas Golden Knights taking on the Colorado Avalanche. Let’s get right into all the betting odds, insights, data and trends to navigate our way to wagering on Game 1 from the Ball Arena in Denver, Colorado.

Vegas Golden Knights vs. Colorado Avalanche Betting Analysis

It’s hard to side with Vegas with the moneyline trends favoring Colorado. The Avs are on a current six-game home winning streak while also taking four of the last five meetings against Vegas. Colorado is also on a 7-0 SU run over its last seven games against clubs from the Pacific Division. Not all is lost for Vegas fans or bettors, though, as the Golden Knights have covered 12 straight puck lines as road underdogs. Also, Colorado has lost the 1P in its last three games – leaving the Vegas 1P Ml at +230 a possibility.

The Under has hit in a whopping nine straight meetings when playing in Denver, with Vegas also seeing six total game goals in five of seven games overall. Moving to player props, Nathan MacKinnon is always solid to find the back of the net but is minus-value. Brett Howden has scored in five straight road games with +340 odds, while Pavel Dorofeyev has scored in his last three games with odds at +200.

Vegas Golden Knights vs. Colorado Avalanche Best Bet, Pick & Prediction

Best Bet: VGS/COL U6.5 (-114)
Score Prediction: Avalanche 4, Golden Knights 2

Vegas Golden Knights vs. Colorado Avalanche Game Odds

Vegas Golden Knights vs. Colorado Avalanche Game Information

  • Date: Wednesday, May 20, 2026
  • Time: 8:10 p.m. ET
  • Network: ESPN
  • Location: Denver, Colorado
  • Venue: Ball Arena – 6.5 goals per game; 21-23-2 O/U
  • Series Score: Tied 0-0

Vegas Golden Knights vs. Colorado Avalanche Betting Resources

Vegas Golden Knights vs. Colorado Avalanche Key Players

Vegas Golden Knights

  • Pavel Dorofeyev – Last Game: (2 Goals, 0 Assists)
  • Mitch Marner – Last Game: (1 Goal, 1 Assist)
  • Tomas Hertl – Last Game: (0 Goals, 1 Assist)

Colorado Avalanche

  • Nathan MacKinnon – Last Game: (1 Goal, 0 Assists)
  • Martin Necas – Last Game: (0 Goals, 2 Assists)
  • Brent Burns – Last Game: (0 Goals, 2 Assists)

Photo Credit: AP/David Zalubowski

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Thom Cunningham is the Lineups.com News Editor and has been involved with sports media for almost two decades at Spectrum, VegasInsider.com, Oddschecker, VSiN and much more as a content producer - focused on the betting and gaming space over the last decade tracking insights, data analytics and covering various markets from the NFL to the Oscars. 

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