MLB Schedule for Today & 2025 Season

Whether you're planning a trip to the ballpark or just trying to catch every big matchup, the MLB schedule page has you covered. It lays out every game for all 30 teams, so you never miss a pitch—from Opening Day to the postseason chase. Perfect for fans who want to follow their team's journey or catch marquee matchups around the league. For a closer look at who’s taking the field each day, check out the latest lineups on the MLB lineups page.

Whether you're planning a trip to the ballpark or just trying to catch every big matchup, the MLB schedule page has you covered. It lays out every game for all 30 teams, so you never miss a pitch—from Opening Day to the postseason chase. Perfect for fans who want to follow their team's journey or catch marquee matchups around the league. For a closer look at who’s taking the field each day, check out the latest lineups on the MLB lineups page.

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Saturday, 5/17/25

Away Team Home Team Time Away Starting Pitcher Home Starting Pitcher Starting Lineup Starting Lineup Matchup
New York Mets New York Mets (27-17) New York Yankees New York Yankees (26-18) 5:05 pm GMT Griffin Canning G. Canning (R), 4-1 Carlos Rodon C. Rodon (L), 5-3 Mets Yankees Mets at Yankees
Chicago White Sox Chicago White Sox (14-30) Chicago Cubs Chicago Cubs (26-17) 6:20 pm GMT Shane Smith S. Smith (R), 1-3 Matthew Boyd M. Boyd (L), 3-2 White Sox Cubs White Sox at Cubs
Detroit Tigers Detroit Tigers (30-15) Toronto Blue Jays Toronto Blue Jays (21-23) 7:07 pm GMT Reese Olson R. Olson (R), 4-3 Jose Urena J. Urena (R), 0-0 Tigers Blue Jays Tigers at Blue Jays
Washington Nationals Washington Nationals (19-27) Baltimore Orioles Baltimore Orioles (15-28) 8:05 pm GMT Jake Irvin J. Irvin (R), 2-1 Cade Povich C. Povich (L), 1-3 Nationals Orioles Nationals at Orioles
Tampa Bay Rays Tampa Bay Rays (19-24) Miami Marlins Miami Marlins (17-26) 8:10 pm GMT Drew Rasmussen D. Rasmussen (R), 1-4 Sandy Alcantara S. Alcantara (R), 2-5 Rays Marlins Rays at Marlins
Pittsburgh Pirates Pittsburgh Pirates (14-30) Philadelphia Phillies Philadelphia Phillies (26-18) 10:05 pm GMT Carmen Mlodzinski C. Mlodzinski (R), 1-3 Zack Wheeler Z. Wheeler (R), 4-1 Pirates Phillies Pirates at Phillies
Cleveland Guardians Cleveland Guardians (25-19) Cincinnati Reds Cincinnati Reds (22-24) 10:40 pm GMT Luis Ortiz L. Ortiz (R), 2-4 Andrew Abbott A. Abbott (L), 2-0 Guardians Reds Guardians at Reds
Houston Astros Houston Astros (23-21) Texas Rangers Texas Rangers (24-21) 11:05 pm GMT Ronel Blanco R. Blanco (R), 3-3 Tyler Mahle T. Mahle (R), 4-1 Astros Rangers Astros at Rangers
St. Louis Cardinals St. Louis Cardinals (25-20) Kansas City Royals Kansas City Royals (25-21) 11:10 pm GMT Miles Mikolas M. Mikolas (R), 2-2 Seth Lugo S. Lugo (R), 3-4 Cardinals Royals Cardinals at Royals
Atlanta Braves Atlanta Braves (23-22) Boston Red Sox Boston Red Sox (22-24) 11:15 pm GMT Grant Holmes G. Holmes (R), 2-3 Lucas Giolito L. Giolito (R), 1-1 Braves Red Sox Braves at Red Sox
Minnesota Twins Minnesota Twins (24-20) Milwaukee Brewers Milwaukee Brewers (21-23) 11:15 pm GMT Pablo Lopez P. Lopez (R), 3-2 Tobias Myers T. Myers (R), 1-0 Twins Brewers Twins at Brewers

Sunday, 5/18/25

Away Team Home Team Time Away Starting Pitcher Home Starting Pitcher Starting Lineup Starting Lineup Matchup
Colorado Rockies Colorado Rockies (7-36) Arizona Diamondbacks Arizona Diamondbacks (23-19) 12:10 am GMT German Marquez G. Marquez (R), 1-6 Zac Gallen Z. Gallen (R), 3-5 Rockies Diamondbacks Rockies at Diamondbacks
Seattle Mariners Seattle Mariners (23-18) San Diego Padres San Diego Padres (27-15) 12:40 am GMT Bryce Miller B. Miller (R), 2-4 Nick Pivetta N. Pivetta (R), 5-2 Mariners Padres Mariners at Padres
Athletics Athletics (20-22) San Francisco Giants San Francisco Giants (24-19) 1:05 am GMT Luis Severino L. Severino (R), 1-4 Landen Roupp L. Roupp (R), 2-3 Athletics Giants Athletics at Giants
Los Angeles Angels Los Angeles Angels (17-24) Los Angeles Dodgers Los Angeles Dodgers (27-15) 1:10 am GMT Tyler Anderson T. Anderson (L), 2-1 Tony Gonsolin T. Gonsolin (R), 2-0 Angels Dodgers Angels at Dodgers
Houston Astros Houston Astros (23-21) Texas Rangers Texas Rangers (24-21) 5:05 pm GMT Hayden Wesneski H. Wesneski (R), 1-3 Jack Leiter J. Leiter (R), 3-2 Astros Rangers Astros at Rangers
Pittsburgh Pirates Pittsburgh Pirates (14-30) Philadelphia Phillies Philadelphia Phillies (26-18) 5:35 pm GMT Paul Skenes P. Skenes (R), 3-4 Cristopher Sanchez C. Sanchez (L), 4-1 Pirates Phillies Pirates at Phillies
Atlanta Braves Atlanta Braves (23-22) Boston Red Sox Boston Red Sox (22-24) 5:35 pm GMT Spencer Schwellenbach S. Schwellenbach (R), 2-3 Tanner Houck T. Houck (R), 0-3 Braves Red Sox Braves at Red Sox
Washington Nationals Washington Nationals (19-27) Baltimore Orioles Baltimore Orioles (15-28) 5:35 pm GMT Mike Soroka M. Soroka (R), 0-2 Cade Povich C. Povich (L), 1-3 Nationals Orioles Nationals at Orioles
Detroit Tigers Detroit Tigers (30-15) Toronto Blue Jays Toronto Blue Jays (21-23) 5:37 pm GMT Jackson Jobe J. Jobe (R), 3-0 Jose Berrios J. Berrios (R), 1-1 Tigers Blue Jays Tigers at Blue Jays
Tampa Bay Rays Tampa Bay Rays (19-24) Miami Marlins Miami Marlins (17-26) 5:40 pm GMT Shane Baz S. Baz (R), 3-2 Cal Quantrill C. Quantrill (R), 2-4 Rays Marlins Rays at Marlins
Cleveland Guardians Cleveland Guardians (25-19) Cincinnati Reds Cincinnati Reds (22-24) 5:40 pm GMT Ben Lively B. Lively (R), 2-2 Chase Petty C. Petty (R), 0-2 Guardians Reds Guardians at Reds
Minnesota Twins Minnesota Twins (24-20) Milwaukee Brewers Milwaukee Brewers (21-23) 6:10 pm GMT Simeon Woods-Richardson S. Woods-Richardson (R), 2-2 Chad Patrick C. Patrick (R), 2-4 Twins Brewers Twins at Brewers
St. Louis Cardinals St. Louis Cardinals (25-20) Kansas City Royals Kansas City Royals (25-21) 6:10 pm GMT Matthew Liberatore M. Liberatore (L), 3-3 Michael Wacha M. Wacha (R), 3-4 Cardinals Royals Cardinals at Royals
Chicago White Sox Chicago White Sox (14-30) Chicago Cubs Chicago Cubs (26-17) 6:20 pm GMT Jonathan Cannon J. Cannon (R), 2-4 Colin Rea C. Rea (R), 3-0 White Sox Cubs White Sox at Cubs
Athletics Athletics (20-22) San Francisco Giants San Francisco Giants (24-19) 8:05 pm GMT Jeffrey Springs J. Springs (L), 5-3 Justin Verlander J. Verlander (R), 0-3 Athletics Giants Athletics at Giants
Los Angeles Angels Los Angeles Angels (17-24) Los Angeles Dodgers Los Angeles Dodgers (27-15) 8:10 pm GMT Yusei Kikuchi Y. Kikuchi (L), 0-4 Tony Gonsolin T. Gonsolin (R), 2-0 Angels Dodgers Angels at Dodgers
Colorado Rockies Colorado Rockies (7-36) Arizona Diamondbacks Arizona Diamondbacks (23-19) 8:10 pm GMT Chase Dollander C. Dollander (R), 2-4 Merrill Kelly M. Kelly (R), 4-2 Rockies Diamondbacks Rockies at Diamondbacks
Seattle Mariners Seattle Mariners (23-18) San Diego Padres San Diego Padres (27-15) 8:10 pm GMT Emerson Hancock E. Hancock (R), 1-2 Michael King M. King (R), 4-1 Mariners Padres Mariners at Padres
New York Mets New York Mets (27-17) New York Yankees New York Yankees (26-18) 11:10 pm GMT David Peterson D. Peterson (L), 2-2 Max Fried M. Fried (L), 6-0 Mets Yankees Mets at Yankees

Monday, 5/19/25

Tuesday, 5/20/25

Away Team Home Team Time Away Starting Pitcher Home Starting Pitcher Starting Lineup Starting Lineup Matchup
Philadelphia Phillies Philadelphia Phillies (26-18) Colorado Rockies Colorado Rockies (7-36) 12:40 am GMT Jesus Luzardo J. Luzardo (L), 4-0 Kyle Freeland K. Freeland (L), 0-6 Phillies Rockies
Kansas City Royals Kansas City Royals (25-21) San Francisco Giants San Francisco Giants (24-19) 1:45 am GMT Kris Bubic K. Bubic (L), 4-2 Robbie Ray R. Ray (L), 6-0 Royals Giants
Los Angeles Angels Los Angeles Angels (17-24) Athletics Athletics (20-22) 2:05 am GMT Jose Soriano J. Soriano (R), 2-4 Gunnar Hoglund G. Hoglund (R), 1-1 Angels Athletics
Arizona Diamondbacks Arizona Diamondbacks (23-19) Los Angeles Dodgers Los Angeles Dodgers (27-15) 2:10 am GMT Brandon Pfaadt B. Pfaadt (R), 6-3 Yoshinobu Yamamoto Y. Yamamoto (R), 4-3 Diamondbacks Dodgers
Cincinnati Reds Cincinnati Reds (22-24) Pittsburgh Pirates Pittsburgh Pirates (14-30) 10:40 pm GMT Nick Martinez N. Martinez (R), 2-4 Bailey Falter B. Falter (L), 2-3 Reds Pirates
Chicago Cubs Chicago Cubs (26-17) Miami Marlins Miami Marlins (17-26) 10:40 pm GMT Jameson Taillon J. Taillon (R), 2-3 Ryan Weathers R. Weathers (L), 1-0 Cubs Marlins
Atlanta Braves Atlanta Braves (23-22) Washington Nationals Washington Nationals (19-27) 10:45 pm GMT Bryce Elder B. Elder (R), 2-2 Mitchell Parker M. Parker (L), 3-3 Braves Nationals
New York Mets New York Mets (27-17) Boston Red Sox Boston Red Sox (22-24) 10:45 pm GMT Clay Holmes C. Holmes (R), 5-2 Walker Buehler W. Buehler (R), 4-1 Mets Red Sox
Houston Astros Houston Astros (23-21) Tampa Bay Rays Tampa Bay Rays (19-24) 11:05 pm GMT Ryan Gusto R. Gusto (R), 3-2 Zack Littell Z. Littell (R), 3-5 Astros Rays
Texas Rangers Texas Rangers (24-21) New York Yankees New York Yankees (26-18) 11:05 pm GMT Patrick Corbin P. Corbin (L), 3-2 Max Fried M. Fried (L), 6-0 Rangers Yankees
San Diego Padres San Diego Padres (27-15) Toronto Blue Jays Toronto Blue Jays (21-23) 11:07 pm GMT Dylan Cease D. Cease (R), 1-2 Chris Bassitt C. Bassitt (R), 3-2 Padres Blue Jays
Seattle Mariners Seattle Mariners (23-18) Chicago White Sox Chicago White Sox (14-30) 11:40 pm GMT Luis Castillo L. Castillo (R), 3-3 Bryse Wilson B. Wilson (R), 0-2 Mariners White Sox
Cleveland Guardians Cleveland Guardians (25-19) Minnesota Twins Minnesota Twins (24-20) 11:40 pm GMT Gavin Williams G. Williams (R), 3-2 Chris Paddack C. Paddack (R), 2-3 Guardians Twins
Baltimore Orioles Baltimore Orioles (15-28) Milwaukee Brewers Milwaukee Brewers (21-23) 11:40 pm GMT Tomoyuki Sugano T. Sugano (R), 4-3 Jose Quintana J. Quintana (L), 4-1 Orioles Brewers
Detroit Tigers Detroit Tigers (30-15) St. Louis Cardinals St. Louis Cardinals (25-20) 11:45 pm GMT Tarik Skubal T. Skubal (L), 4-2 Erick Fedde E. Fedde (R), 3-3 Tigers Cardinals

Wednesday, 5/21/25

Away Team Home Team Time Away Starting Pitcher Home Starting Pitcher Starting Lineup Starting Lineup Matchup
Philadelphia Phillies Philadelphia Phillies (26-18) Colorado Rockies Colorado Rockies (7-36) 12:40 am GMT Aaron Nola A. Nola (R), 1-7 Antonio Senzatela A. Senzatela (R), 1-7 Phillies Rockies
Kansas City Royals Kansas City Royals (25-21) San Francisco Giants San Francisco Giants (24-19) 1:45 am GMT Michael Lorenzen M. Lorenzen (R), 3-4 Jordan Hicks J. Hicks (R), 1-5 Royals Giants
Los Angeles Angels Los Angeles Angels (17-24) Athletics Athletics (20-22) 2:05 am GMT Kyle Hendricks K. Hendricks (R), 1-5 Osvaldo Bido O. Bido (R), 2-4 Angels Athletics
Arizona Diamondbacks Arizona Diamondbacks (23-19) Los Angeles Dodgers Los Angeles Dodgers (27-15) 2:10 am GMT Eduardo Rodriguez E. Rodriguez (L), 1-3 Roki Sasaki R. Sasaki (R), 1-1 Diamondbacks Dodgers
Cincinnati Reds Cincinnati Reds (22-24) Pittsburgh Pirates Pittsburgh Pirates (14-30) 4:35 pm GMT Brady Singer B. Singer (R), 5-2 Andrew Heaney A. Heaney (L), 1-3 Reds Pirates
Baltimore Orioles Baltimore Orioles (15-28) Milwaukee Brewers Milwaukee Brewers (21-23) 5:10 pm GMT Kyle Gibson K. Gibson (R), 0-2 Tobias Myers T. Myers (R), 1-0 Orioles Brewers
Cleveland Guardians Cleveland Guardians (25-19) Minnesota Twins Minnesota Twins (24-20) 5:10 pm GMT Tanner Bibee T. Bibee (R), 3-4 Joe Ryan J. Ryan (R), 4-2 Guardians Twins
Chicago Cubs Chicago Cubs (26-17) Miami Marlins Miami Marlins (17-26) 5:10 pm GMT Cade Horton C. Horton (R), 2-0 Max Meyer M. Meyer (R), 3-4 Cubs Marlins
Houston Astros Houston Astros (23-21) Tampa Bay Rays Tampa Bay Rays (19-24) 5:10 pm GMT Hunter Brown H. Brown (R), 6-2 Taj Bradley T. Bradley (R), 3-3 Astros Rays
Detroit Tigers Detroit Tigers (30-15) St. Louis Cardinals St. Louis Cardinals (25-20) 5:15 pm GMT Jack Flaherty J. Flaherty (R), 2-5 Andre Pallante A. Pallante (R), 4-2 Tigers Cardinals
Seattle Mariners Seattle Mariners (23-18) Chicago White Sox Chicago White Sox (14-30) 6:10 pm GMT Logan Evans L. Evans (R), 1-1 Shane Smith S. Smith (R), 1-3 Mariners White Sox
Kansas City Royals Kansas City Royals (25-21) San Francisco Giants San Francisco Giants (24-19) 7:45 pm GMT Cole Ragans C. Ragans (L), 2-3 Logan Webb L. Webb (R), 3-3 Royals Giants
Atlanta Braves Atlanta Braves (23-22) Washington Nationals Washington Nationals (19-27) 10:45 pm GMT A.J. Smith-Shawver A.J. Smith-Shawver (R), 3-2 Trevor Williams T. Williams (R), 2-5 Braves Nationals
New York Mets New York Mets (27-17) Boston Red Sox Boston Red Sox (22-24) 10:45 pm GMT Tylor Megill T. Megill (R), 3-4 Garrett Crochet G. Crochet (L), 4-3 Mets Red Sox
Texas Rangers Texas Rangers (24-21) New York Yankees New York Yankees (26-18) 11:05 pm GMT Jacob deGrom J. DeGrom (R), 4-1 Will Warren W. Warren (R), 2-2 Rangers Yankees
San Diego Padres San Diego Padres (27-15) Toronto Blue Jays Toronto Blue Jays (21-23) 11:07 pm GMT Randy Vasquez R. Vasquez (R), 3-3 Kevin Gausman K. Gausman (R), 3-4 Padres Blue Jays

Thursday, 5/22/25

Away Team Home Team Time Away Starting Pitcher Home Starting Pitcher Starting Lineup Starting Lineup Matchup
Philadelphia Phillies Philadelphia Phillies (26-18) Colorado Rockies Colorado Rockies (7-36) 12:40 am GMT Ranger Suarez R. Suarez (L), 2-0 Bradley Blalock B. Blalock (R), 0-2 Phillies Rockies
Los Angeles Angels Los Angeles Angels (17-24) Athletics Athletics (20-22) 2:05 am GMT Jack Kochanowicz J. Kochanowicz (R), 2-4 JP Sears J. Sears (L), 3-2 Angels Athletics
Arizona Diamondbacks Arizona Diamondbacks (23-19) Los Angeles Dodgers Los Angeles Dodgers (27-15) 2:10 am GMT Corbin Burnes C. Burnes (R), 2-1 Dustin May D. May (R), 1-3 Diamondbacks Dodgers
Texas Rangers Texas Rangers (24-21) New York Yankees New York Yankees (26-18) 4:35 pm GMT Nathan Eovaldi N. Eovaldi (R), 4-2 Carlos Rodon C. Rodon (L), 5-3 Rangers Yankees
San Diego Padres San Diego Padres (27-15) Toronto Blue Jays Toronto Blue Jays (21-23) 5:07 pm GMT Stephen Kolek S. Kolek (R), 2-0 Bowden Francis B. Francis (R), 2-6 Padres Blue Jays
Philadelphia Phillies Philadelphia Phillies (26-18) Colorado Rockies Colorado Rockies (7-36) 7:10 pm GMT Zack Wheeler Z. Wheeler (R), 4-1 German Marquez G. Marquez (R), 1-6 Phillies Rockies
Los Angeles Angels Los Angeles Angels (17-24) Athletics Athletics (20-22) 7:35 pm GMT Tyler Anderson T. Anderson (L), 2-1 Luis Severino L. Severino (R), 1-4 Angels Athletics
Milwaukee Brewers Milwaukee Brewers (21-23) Pittsburgh Pirates Pittsburgh Pirates (14-30) 10:40 pm GMT Tobias Myers T. Myers (R), 1-0 Carmen Mlodzinski C. Mlodzinski (R), 1-3 Brewers Pirates
Cleveland Guardians Cleveland Guardians (25-19) Detroit Tigers Detroit Tigers (30-15) 10:40 pm GMT Luis Ortiz L. Ortiz (R), 2-4 Reese Olson R. Olson (R), 4-3 Guardians Tigers
Atlanta Braves Atlanta Braves (23-22) Washington Nationals Washington Nationals (19-27) 10:45 pm GMT Chris Sale C. Sale (L), 2-3 MacKenzie Gore M. Gore (L), 2-4 Braves Nationals
Baltimore Orioles Baltimore Orioles (15-28) Boston Red Sox Boston Red Sox (22-24) 10:45 pm GMT Zach Eflin Z. Eflin (R), 3-1 Lucas Giolito L. Giolito (R), 1-1 Orioles Red Sox

Friday, 5/23/25

Away Team Home Team Time Away Starting Pitcher Home Starting Pitcher Starting Lineup Starting Lineup Matchup
Seattle Mariners Seattle Mariners (23-18) Houston Astros Houston Astros (23-21) 12:10 am GMT Bryce Miller B. Miller (R), 2-4 Lance McCullers Jr. L. McCullers Jr. (R), 0-1 Mariners Astros
Milwaukee Brewers Milwaukee Brewers (21-23) Pittsburgh Pirates Pittsburgh Pirates (14-30) 10:40 pm GMT Freddy Peralta F. Peralta (R), 4-2 Paul Skenes P. Skenes (R), 3-4 Brewers Pirates
Chicago Cubs Chicago Cubs (26-17) Cincinnati Reds Cincinnati Reds (22-24) 10:40 pm GMT Matthew Boyd M. Boyd (L), 3-2 Chase Petty C. Petty (R), 0-2 Cubs Reds
San Francisco Giants San Francisco Giants (24-19) Washington Nationals Washington Nationals (19-27) 10:45 pm GMT Landen Roupp L. Roupp (R), 2-3 Jake Irvin J. Irvin (R), 2-1 Giants Nationals
Toronto Blue Jays Toronto Blue Jays (21-23) Tampa Bay Rays Tampa Bay Rays (19-24) 11:05 pm GMT Jose Urena J. Urena (R), 0-0 Drew Rasmussen D. Rasmussen (R), 1-4 Blue Jays Rays
Cleveland Guardians Cleveland Guardians (25-19) Detroit Tigers Detroit Tigers (30-15) 11:10 pm GMT Ben Lively B. Lively (R), 2-2 Jackson Jobe J. Jobe (R), 3-0 Guardians Tigers
Baltimore Orioles Baltimore Orioles (15-28) Boston Red Sox Boston Red Sox (22-24) 11:10 pm GMT Cade Povich C. Povich (L), 1-3 Tanner Houck T. Houck (R), 0-3 Orioles Red Sox
Los Angeles Dodgers Los Angeles Dodgers (27-15) New York Mets New York Mets (27-17) 11:10 pm GMT Tony Gonsolin T. Gonsolin (R), 2-0 Griffin Canning G. Canning (R), 4-1 Dodgers Mets
San Diego Padres San Diego Padres (27-15) Atlanta Braves Atlanta Braves (23-22) 11:15 pm GMT Nick Pivetta N. Pivetta (R), 5-2 Grant Holmes G. Holmes (R), 2-3 Padres Braves
Texas Rangers Texas Rangers (24-21) Chicago White Sox Chicago White Sox (14-30) 11:40 pm GMT Tyler Mahle T. Mahle (R), 4-1 Sean Burke S. Burke (R), 2-4 Rangers White Sox

Saturday, 5/24/25

MLB Schedule 2025: Key Series, Calendar Breakdown & Betting Angles

The 2025 MLB schedule covers all 30 teams across 162 games each, spanning from Opening Day in March through late September. With new travel patterns, balanced matchups, and expanded interleague play, every week brings unique betting and fantasy angles. Following the MLB calendar closely helps bettors plan ahead for high-value spots and fatigue-related fades. Fantasy players benefit too by identifying two-start pitchers, hitter-friendly stretches, and key rest days in advance.

Major series between division rivals often have playoff implications, especially in the second half. Interleague games and travel-heavy weeks also impact team performance and lineup construction. Tracking the schedule helps predict bullpen fatigue, pinch-hit opportunities, and platoon usage. Bettors and DFS players alike gain an edge by understanding how the schedule shapes performance over time.

How the MLB Schedule Works

Each MLB team plays 162 games: 52 against division opponents, 64 against the rest of their league, and 46 interleague games under the new balanced format. This structure ensures that every team faces every other club at least once per season, increasing exposure to unfamiliar pitchers and stadiums. These factors lead to more volatile prop markets, especially early in new series. Bettors who track travel and league matchups gain a huge advantage over time.

The 2025 season also includes built-in off days, doubleheaders, and holiday weekend games, which can skew player usage. West Coast teams often face difficult travel, which bettors can exploit in total runs and bullpen props. Fantasy managers can use schedule strength to target sleeper picks and favorable matchups in weekly formats. Understanding the rhythm of the MLB calendar helps you stay ahead in all formats.

Key Matchups on the 2025 MLB Schedule

Rivalry games like Yankees vs. Red Sox, Dodgers vs. Giants, and Cubs vs. Cardinals headline the marquee matchups of 2025. These series often feature playoff-like intensity and expanded betting menus across all major sportsbooks. They’re also popular for promos like same-game parlays, milestone prop boosts, and national broadcast bonuses. Fantasy and DFS players should expect strong ownership spikes and inflated lines during these contests.

Holiday series such as Memorial Day, Independence Day, and Labor Day are also heavily wagered, with sportsbooks offering promos and odds boosts. These games typically include giveaways, larger crowds, and primetime lineups. Watch for shifts in bullpen usage and pinch-hitting decisions based on roster depth. These matchups are often higher-scoring and provide great value on overs and home run props.

MLB Schedule & Sports Betting Strategy

The grind of a 162-game schedule introduces variance and market inefficiencies, which sharp bettors use to their advantage. Teams coming off travel days or playing their third city in four days may underperform, offering fade spots. Look for pitcher mismatches when aces are lined up against road-weary squads. Bettors should also monitor bullpen trends, especially in the second half of long road trips.

Back-to-back series with the same opponent can cause sportsbooks to overcorrect based on small sample sizes. Watching for overreaction lines is key after blowouts or injury-related games. Home-field advantage also varies—some teams perform better in day games while others dominate at night. Advanced planning around the schedule allows for better pre-game betting decisions and sharper in-game strategy.

Best Sportsbook Promos for MLB Schedule-Based Betting

Use these rotating sportsbook promos to boost your ROI on 2025 MLB bets, especially during featured series and national matchups. Many offers are tied to specific days, players, or team milestones reflected on the calendar. These promotions change weekly and often respond to schedule-driven events like rivalries or holidays. Betting with promos adds extra value even when odds are tight.

How the MLB Schedule Affects DFS Strategy

The MLB schedule dictates everything from player rest days to two-start pitcher weeks, directly influencing DFS strategy. Doubleheaders and travel days often result in backup players starting, providing salary relief and low-ownership upside. DFS slates also shift based on game timing, with early slates or night-only contests requiring calendar awareness. Smart players study team travel and fatigue to find hidden gems and stack targets.

Short homestands or cross-country road trips tend to impact offensive consistency. Teams returning home from extended trips may start slow, making them fade candidates in early DFS builds. Weather, stadium, and opponent alignments also vary by schedule structure. Planning your DFS strategy around the calendar leads to better lineup construction and higher ROI.

National Broadcast Games & Betting Trends

Games broadcast on ESPN, FOX, or MLB Network typically have more prop markets, boosted odds, and promotional tie-ins. These contests often see increased betting volume and sharper line movement based on public action. Books may inflate odds on stars or popular teams, creating opportunities for value on lesser-known players. Targeting milestone bets or contrarian props during national games is a proven edge.

Fantasy and DFS contests are also more competitive during these slates, with higher entries and more optimal builds. Look for pricing inefficiencies on bench players or relievers who may be thrust into spotlight roles. In-game betting during national broadcasts often includes inning-specific props and alternate lines. Smart bettors monitor live matchups and bullpen availability to strike at the best time.

How to Track the MLB Schedule Daily

Use trusted sources like MLB.com, fantasy tools, and betting apps to stay updated on the 2025 schedule. These platforms offer alerts on doubleheaders, game postponements, and rescheduled matchups. Some DFS tools sync daily slates with the calendar and provide matchup-specific breakdowns. Staying organized allows you to plan your bets and lineups in advance for every matchup type.

Many sportsbooks also post calendar-based promos or look-ahead odds for key series. These early lines allow sharp bettors to get in ahead of market movement. For fantasy players, tracking the calendar helps with bench rotation, streaming options, and waiver priority. Being ahead of schedule shifts means being ahead of the competition.