MLB Home Run Predictions, Picks, Props, Odds for Friday, April 17, 2026

We nailed Jose Ramirez to go yard on Thursday, making it a profitable day. We’ll look to keep it rolling on Friday’s slate.

Today, we’re going with Yordan Alvarez, Austin Riley, and Willy Adames. Each of these hitters has a strong track record and is in a favorable situation to hit home runs.

Keep reading to find out about our MLB home run predictions for today. Also, be sure to check out our daily MLB betting trends page.

Click any odds below to place a wager. For more sportsbook promos, we highly recommend checking out the best sports betting sites.

2026 MLB HR Props Record: 6-52 (-2.45 units) 

Home Run Prop Predictions & Odds: MLB HR Best Bets for Friday, April 17

Yordan Alvarez Home Run Odds

Yordan Alvarez has been an absolute monster this season, slashing .328/.483/.731 with seven home runs in 89 plate appearances. The plate discipline metrics look phenomenal: 20.2% walk rate, 11.2% strikeout rate. The batted ball numbers are even better: 20.7% barrel rate.

The matchup is on point as well, as Alvarez goes up against Cardinals right-hander Kyle Leahy, who has been disappointing so far, allowing an 8.30 xERA and 16.7% barrel rate. Left-handed hitters have crushed Leahy so far, putting up a .481 wOBA (right-handers have a .226 wOBA against him).

With Alvarez mashing, I’m surprised that we’re able to get him at longer than +300 odds given this favorable matchup. Risk 0.1 units.

Austin Riley Home Run Odds

Austin Riley is off to a slow start, slashing .229/.316/.329 with one home run in 79 plate appearances. However, the plate discipline looks good (11.4 BB%, 17.7 K%). Plus, Riley has an extensive track record, with three 30+ home run seasons under his belt.

On top of that, Riley’s first home run of the season came in his last game, so perhaps this could be the start of a hot streak. There are encouraging signs, as he’s hit safely in five of his last seven games.

Up next is a good spot against Taijuan Walker, who has a 6.59 xERA with a 2.45 HR/9 this season. It’s definitely the right matchup for Riley to hit his second homer of the season, especially in a projected high-scoring game with a 9.5-run total. Risk 0.1 units.

Willy Adames Home Run Odds

Willy Adames is off to a rock-solid start at the plate, slashing .260/.316/.507 with three home runs in 79 plate appearances. The veteran shortstop is hitting the ball hard, as highlighted by an 11.5% barrel rate.

We’re starting to see Adames heat up at the plate, as he’s gone 12-for-36 (.333 BA) with two home runs in his last nine games. He’s got a good matchup next against Nationals’ right-hander Zack Littell.

The former Reds’ innings-eater has put up a 5.35 xERA with a 9.8% barrel rate so far. Even better for this prop is that Littell has already allowed five home runs in only 15 innings.

With that in mind, we’ll take a shot on Adames to hit No. 4 tonight. Risk 0.1 units.

  • Join Lineups’ free sports betting Discord channel, with more than 5,100 community members discussing MLB 24-7-365.

Best Sportsbook Promos For Home Run Prop Predictions

Rank
Sportsbooks
Bonus
Features
Play
1
Up to $1,500
In Bonuses
BetMGM Sportsbook Review
  • Up to $1,500 in Bonus Bets if Your First Bet Doesn't Win*

  • *Bonus Bets Expire in 7 Days. One New Customer Offer Only. Add’l terms. 21+. Gambling Problem? Call 1-800-BETS-OFF

  • Use Bonus Code: BETLINEUPS

2
Bet $10 Get $150
In Bonus Bets Win or Lose
Bet365 Sportsbook Review
  • Bet $10 Get $150 in Bonus Bets Win or Lose

  • 30% Extra on Same Game Parlay Profit

  • T&Cs Apply. GAMBLING PROBLEM? CALL 1-800-MY-RESET. 21+

  • Use Bonus Code: LINEUPSBET

3
Get $350 in Bonus Bets
When You Bet $5 for 7 Days
FanDuel Sportsbook Review
  • Get $350 in Bonus Bets Guaranteed - When You Bet $5 for 7 Days!

  • Available on Desktop, Android & iOS

  • Easy Deposits, Fast Withdrawals

4
Double Your Winnings
On Your Next 10 Wagers
Caesars Sportsbook Review
  • Bet $1, Double Your Winnings on Your Next 10 Wagers (Up to $25 Max Bet Per Boost)

  • Stream NFL Games In-App for Free

  • OH only. 21+.Gambling Problem? Call or text 1-800-MY-RESET

  • Use Promo Code: LINEUPSDYW

5
Up to $1,000
In FanCash Matched Bets
Fanatics Sportsbook Review
  • Get a 100% Bet Match up to $100 in FanCash for 10 Days

  • Earn FanCash & Spend it on Team Swag or More Bets

  • Daily Odds & Profit Boosts on Select Games

6
Bet $5 Get $200 in Bonus Bets
New User Bonus
DraftKings Sportsbook Review
  • Bet $5 Get $200 in Bonus Bets Instantly

  • Plus Get up to $1,000 Deposit Bonus

  • Bet on All Your Favorite Sports With America's Top-Rated Sportsbook

  • To Claim: Click Play Now

Photo Credit: AP/Lindsey Wasson

Post
Frank Ammirante has been creating sports betting and fantasy sports content for 5+ years, specializing in baseball and football, but also writing about basketball, hockey, and soccer. He has also written online casino, sweepstakes casino, prediction markets, and news articles while working as a content editor as well. You may have seen his work at The Game Day, RotoBaller, FantasyPros, Deadspin, Casino.org, and much more. Frank started out in the fantasy sports space and has competed in popular industry events like Tout Wars. His work has recently been published in this year's Fantasy Index fantasy baseball magazine. As an avid Blue Jays fan, Frank is still mourning their World Series loss to the Dodgers, calling it "one of the biggest collapses in sports history."

Hot Betting News Stories

Sign up to our newsletter to get lineups latest hands-on reviews, expert advice, and exclusive offers delivered straight to your inbox.
You are already subscribed to our newsletter. Want to update your preferences data?
Thank you for signing up! You’re all set to receive the latest reviews, expert advice, and exclusive offers straight to your inbox. Stay tuned!
Something went wrong. Please try again later
Sign up to our newsletter to get lineups latest hands-on reviews, expert advice, and exclusive offers delivered straight to your inbox.
You are already subscribed to our newsletter. Want to update your preferences data?
Thank you for signing up! You’re all set to receive the latest reviews, expert advice, and exclusive offers straight to your inbox. Stay tuned!
Something went wrong. Please try again later