Missouri vs. Miami-Florida First Round Game Preview, Picks, Betting Odds & Data

By Thom Cunningham | Mar 19, 2026, 6:14pm

In what should be an electric game, the No. 10 Missouri Tigers face the No. 7 Miami-Florida Hurricanes. Let’s see if this Miami team can have similar success as the other Miami team did in Dayton as we break down betting odds, data and projections for Friday’s late night encounter.

Missouri vs. Miami-Florida Game Information

Date: Friday, Mar. 20, 2026
Time: 10:10 p.m. ET
Network: truTV
Region: West
Location: St. Louis, Missouri
Venue: Enterprise Center

Missouri vs. Miami-Florida Betting Resources

Missouri vs. Miami-Florida Betting Odds

Missouri vs. Miami-Florida Betting Data

Missouri Tigers

Region Odds:
Sweet 16 Odds:
Elite Eight Odds:
Final Four Odds:
National Title Odds:

Seed: No. 10
Record: 20-12
Conference: SEC
PS/G: 79.7
PA/G: 75.3
ORtg: 115.6
DRtg: 109.4

Miami-Florida Hurricanes

Region Odds:
Sweet 16 Odds:
Elite Eight Odds:
Final Four Odds:
National Title Odds:

Seed: No. 7
Record: 25-8
Conference: ACC
PS/G: 81.9
PA/G: 71.2
ORtg: 118.2
DRtg: 102.7

Missouri vs. Miami-Florida Key Players

Missouri Tigers

Mark Mitchell (SR) – 18.3 ppg; 5.3 rpg
Jayden Stone (SR) – 13.2 ppg; 5 rpg

Miami-Florida Hurricanes

Malik Reneau (SR) – 18.8 ppg; 6.6 rpg
Tre Donaldson (SR) – 16.5 ppg; 5.8 apg
Shelton Henderson (FR) – 13,7 ppg; 4.8 rpg

Missouri vs. Miami-Florida Betting Analysis

Although this is not a road game, technically, Miami sports a solid 8-2 ATS mark when playing on the road this season. The Hurricanes have also scored 75 points or more in six straight non-conference games – so the ATS and total markets seem to favor the Hurricanes for now. Miami has also covered five of its last seven games.

For Mizzou, the ATS isn’t as pretty with a current 0-3 ATS skid along with failing to cover three straight games on a neutral court. Before the three-game ATS skid, Missouri did cover four straight along with six of seven games. The point total has good conviction in it when looking at the above Miami trend and Missouri’s recent games – hitting the Over in six of eight games.

Missouri vs. Miami-Florida Best Bet, Pick & Prediction

We actually had the Miami spread penciled in, erased, then put back in. So if you like the Hurricanes then take -2-points all day. There is more than enough conviction in Missouri’s ATS struggles and Miami’s ATS success to go with the Canes. Also, Missouri has lost seven straight non-conference games on a neutral court. We did like the Over, until seeing Missouri has gone Under 141 total points in 5 straight NCAA Tournament games.

Score Prediction: Miami-Florida 79, Missouri 75
Best Bet: Miami-Florida -2 (-110)

Photo Credit: AP/Nell Redmond

Thom Cunningham

Thom Cunningham is the Lineups.com News Editor and has been involved with sports media for almost two decades at Spectrum, VegasInsider.com, Oddschecker, VSiN and much more as a content producer - focused on the betting and gaming space over the last decade tracking insights, data analytics and covering various markets from the NFL to the Oscars.