MLB Home Run Predictions, Picks, Props, Odds for Wednesday, June 10, 2026

By Frank Ammirante | Jun 10, 2026, 8:56am

We had a profitable night on Tuesday, as Randy Arozarena went yard, helping make up for losses on Marcell Ozuna and Wyatt Langford. Let’s make it two winning nights in a row on the Wednesday slate. We’ve been hot lately.

Today, we’re going with Jose Altuve, Randal Grichuk, and Corey Seager. Each of these hitters is in a good spot to hit a home run, including favorable prices.

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2026 MLB HR Props Record: 43-168 (+1.19 units)

Home Run Prop Predictions & Odds: MLB HR Best Bets for Wednesday, June 10

Jose Altuve Home Run Odds

Jose Altuve is a veteran hitter with a strong track record, but he hasn’t gotten it going in his age-36 season, slashing .237/.320/.379 with five home runs in 201 plate appearances.

It’s been a year plagued by injury so far, as Altuve recently returned to action on June 5th.

But one thing Altuve has always done is hit lefties, putting up a 146 wRC+ against them throughout his career (121 wRC+ vs. righties).

He’ll get one tonight in Angels’ left-hander Reid Detmers. While Detmers has an impressive 2.92 xERA on the season, Altuve has had success against him throughout his career, putting up two home runs in 24 plate appearances.

With that in mind, we’ll take a shot on Altuve to hit No. 6 in this spot. Risk 0.1 units.

Randal Grichuk Home Run Odds

Randal Grichuk is currently slashing .267/.297/.547 with six home runs in 91 plate appearances. He’s been an absolute lefty masher this season, putting up a 193 wRC+ against them. At this stage of his career, he’s a weak-side platoon specialist.

We recently saw Grichuk hit two home runs on June 5th. I’ll bet on him to do it again in this spot.

It’s a tough matchup against Chris Sale, who has a 3.33 xERA on the season. However, Grichuk is quite familiar with Sale, homering twice in 30 plate appearances against him.

We’re getting a nicer price here given the tough matchup, so we’ll take a shot on Grichuk in this spot. Risk 0.1 units.

Corey Seager Home Run Odds

Corey Seager is having another disappointing season that has been plagued by injury, currently slashing .185/.284/.363 with eight home runs in 194 plate appearances.

The good news is that he’s hitting the ball hard, including a 15.4% barrel rate, which aligns with his career norms, so there’s no decline there.

I like the matchup in a hitter-friendly environment at Kauffman Stadium tonight. He’s going up against veteran right-hander Seth Lugo, who has a 5.23 xERA on the season.

What’s good about this spot is that Seager has one home run and a .607 expected slugging percentage against Lugo, so there’s some familiarity here.

We recently saw Seager go yard on June 5th, so perhaps he’s slowly getting into a groove. Risk 0.1 units.

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Frank Ammirante

Frank Ammirante has been creating sports betting and fantasy sports content for 5+ years, specializing in baseball and football, but also writing about basketball, hockey, and soccer. He has also written online casino, sweepstakes casino, prediction markets, and news articles while working as a content editor as well. You may have seen his work at The Game Day, RotoBaller, FantasyPros, Deadspin, Casino.org, and much more. Frank started out in the fantasy sports space and has competed in popular industry events like Tout Wars. His work has recently been published in this year's Fantasy Index fantasy baseball magazine. As an avid Blue Jays fan, Frank is still mourning their World Series loss to the Dodgers, calling it "one of the biggest collapses in sports history."