Arizona Cardinals vs Minnesota Vikings Preview (10/30/22): Betting Odds, Prediction, Depth Charts

After a major win on Thursday Night Football, the Arizona Cardinals are on the road to take on the Minnesota Vikings, who are fresh off their bye week. The game features no shortage of offensive talent, with QB Kyler Murray and WR Deandre Hopkins for the Cardinals looking to outgain QB Kirk Cousins and WR Justin Jefferson for the Vikings. There’s the potential for some serious offensive firepower in this matchup, so let’s see what you should expect from a betting perspective.

Arizona Cardinals Vs. Minnesota Vikings Betting Odds

For this Sunday matchup between NFC competitors, the Minnesota Vikings are currently -3.5 point favorites with a total of 49. The Arizona Cardinals are currently 3-3 against the spread with a 5-1 record to the under. Meanwhile, the Minnesota Vikings are now 2-4 against the spread with a 3-3 record to the over/under. The Arizona Cardinals are floating around +155 for moneyline odds, with the Vikings around -180.

Arizona Cardinals Vs. Minnesota Vikings Prediction

The Arizona Cardinals looked rejuvenated with WR Deandre Hopkins, putting up 42 points as the returning receiver hauled in ten catches for 103 yards. However, much of the night’s success was due to the Cards hauling in two pick-sixes, and I believe that the Saints could very well have won last Thursday night without those mistakes. The Cardinals also gave up 494 total yards to New Orleans, and the defense is allowing an average of 25.1 points per game. And they face a much tougher task this week facing off against the Minnesota offense.

Like the Cardinals, the Vikes will have a little extra rest after the bye week, which should help a team that has gone 5-1 straight up but struggled to cover the spread. The offense is putting up a decent 339.8 yards per game, and you feel like the potential has yet to be fully unlocked with weapons like RB Dalvin Cook and WR Adam Thielen. While I believe the offense will have an above-average day, the defense will likely struggle at times against a Cardinals offense that has its top receiver back. Minnesota is allowing 384.5 yards and 23.2 yards per game.

This game isn’t the easiest to decide from an ATS perspective, but I’ve got to go with the Vikings here. The Cardinals have been unpredictable (and even embarrassing) at times, as seen with the 19-9 loss to the Seattle Seahawks. I’m banking on Minnesota to open up the offense as both sides finish with some impressive drives. I’m planning on laying the points with the Vikings at home and taking the over.

Cardinals vs Vikings Betting Trends

  • Minnesota Vikings: 6-1 Over streak at home
  • Arizona Cardinals: 2-5 ATS streak after a win
  • Minnesota Vikings: 5-1 Over streak after bye week

Cardinals vs Vikings Key Injuries

Arizona Cardinals Injuries: Matt Prater (Q), James Conner (Q), Darrel Williams (Q), Rashard Lawrence (Q), Max Garcia (Q) Dennis Gardeck (Q), Trayvon Mullen (Q), Rodney Hudson (Q)

Minnesota Vikings Injuries: D.J. Wonnum (Q)

Cardinals vs Vikings Key Matchups

Check out the key matchups and mismatches for Arizona Cardinals vs Minnesota Vikings below.

Minnesota Vikings WRs vs Arizona Cardinals Secondary

WR Justin Jefferson isn’t just one of the best young wide receivers in the league, he’s developing into one of the best overall. The WR is leading the team with 654 yards and a 14.2 average per reception. His supporting cast of Adam Thielen (284 yards) and K.J. Osborn (177 yards) has been overshadowed, but all three have the opportunity to shine against the Arizona secondary. The Cardinals just allowed a New Orleans receiving corps missing key starters to rack up 409 yards in the passing game with a backup QB playing. The defense is already allowing 258.6 yards in the air per game, and it could be a long day for Cardinals cornerbacks at U.S. Bank Stadium.

Kyler Murray vs Minnesota Vikings Defense

Cardinals QB Kyler Murray has a great opportunity against a middle-of-the-road defense this week to prove his doubters wrong. Murray has been inconsistent, but he has an opportunity against a Vikings defense that tends to struggle against mobile QBs. When Minnesota faced off against the Philadelphia Eagles, QB Jalen Hurts put up 333 yards in the air with an additional 57 yards on the ground. The team also allowed Chicago Bears QB Justin Fields to rack up 47 rushing yards with a 5.9 average. Murray can do some damage with his legs (as seen with his 100 yards against the Seattle Seahawks), which could be the key to keeping up with the Vikings offense.

Arizona Cardinals Depth Chart

QB: Kyler Murray
RB1: James Conner
RB2: Eno Benjamin
LWR: DeAndre Hopkins
RWR: Robbie Anderson
SWR: Rondale Moore
TE1: Zach Ertz

Minnesota Vikings Depth Chart

QB: Kirk Cousins
RB1: Dalvin Cook
RB2: Alexander Mattison
LWR: Justin Jefferson
RWR: Adam Thielen
SWR: K.J. Osborn
TE1: Irv Smith Jr.

Anthony Elio is the Lead Writer for, focusing on sports betting, online casino gaming, and horse racing. He covers state betting handles, sportsbook partnerships, operator news, and NHL picks. Outside of his work with LINEUPS, Elio has also written for Daily Fantasy Cafe, Innovation & Tech Today, Krazy Coupon Lady, and Residential Tech Today.

Hot NFL Stories