San Francisco 49ers vs. Seattle Seahawks Matchup Preview (12/5/21): Betting Odds, Depth Charts, Live Stream (Watch Online)

San Francisco 49ers vs. Seattle Seahawks Matchup Preview (12/5/21)

This Sunday in an NFC West rivalry game, the San Francisco 49ers head to rainy Seattle to take on Russell Wilson and the Seahawks. The 49ers have had quite the turnaround season. After losing four straight games from week 3-7, one of which was against the Seahawks, they’ve turned it around, and are on a three game winning streak, scoring 30+ points each game. They are currently 6-5 and have a hold on a playoff spot. On the opposite hand, the Seahawks look the worst that they have in years and many are starting to wonder if this is the end of an era for them. Certainly their Legion of Boom days are gone. They are 3-8 after losing to the Washington Football Team on Monday and might be the most frustrating team in the league to watch right now. Nonetheless, this is a big rivalry game and is usually a pretty entertaining game to watch so you’ll want to tune in on Sunday. 

San Francisco 49ers vs. Seattle Seahawks Betting Odds

The 49ers are the 3.5-favored team in this matchup and the over/under is set at 46 points. While both teams are 5-6 at covering this year in general, the Seahawks are 1-4 at covering at home while the 49ers are 3-2 on covering on the road, and 4-1 on the road overall. The Seahawks have struggled to hit the over at all this season, particularly at home, where they are 1-4 on hitting it. The 49ers aren’t much better at hitting this as they are 2-3 on hitting the over when they are not at their home field, but their away game record helps them recuperate that. This is an interesting matchup because although the 49ers are obviously the better team, the Seahawks have one of the lowest point totals against them in the league, and really haven’t been blown out this year aside from the Green Bay game. If this wasn’t a division rival, I would say that the Seahawks would get blown out, but I think it will be a closer game than it realistically should be. Nonetheless, the Seahawks have shown that they can’t play a full four quarters, so I’m taking the 49ers. 

My prediction: 49ers win, 24-21, Seahawks cover, under 46 points

US States with Legal Sports Gambling

TV Schedule

Date: 12/5/21
Time: 2:25 PM ET
Location: Lumen Field – Seattle, WA
TV Coverage: CBS

San Francisco 49ers vs. Seattle Seahawks Live Stream

Where can you watch 49ers vs. Seahawks online? You can stream this game, and many other NFL games live online with Hulu. Hulu has a 7 Day free trial and is cheaper than cable options at $5.99/month. Watch 49ers vs. Seahawks Free Online Now.

hulu free trial

San Francisco 49ers Analysis

The 49ers have been a fun team to watch in recent weeks. After a rocky start to the season, they have made the comeback of the year. They sit in the dead center of the league in passing yards per game with 234.2 and sixth in the league in rushing yards with 130.9 per game. They total 365.1 yards per game and Seattle allows at least that, so they should not have a problem getting down the field this week. 

Deebo Samuel has been huge for the 49ers this season – he has 1,006 receiving yards this season, which is the fourth most across all receivers in the league, 203 rushing yards, 5 rushing touchdowns and 5 receiving touchdowns. Bad news for the 49ers is that he is listed as “doubtful” for this game. He has been crucial to their offensive success this year and considering his absence and how many passing yards the Seahawks conceive, they will likely target Brandon Aiyuk more this game. He has been targeted 48 times and caught for 432 yards, has 3 touchdowns, and averages 13.5 yards per reception. Elijah Mitchell also threatens the Seattle defense, averaging 86.6 yards per game. He had an incredible game last week against the Vikings, tallying 133 yards over 27 attempts, and had a touchdown. The offense overall averages 25.5 points per game which is five more than the Seahawks have been willing to give up this season. 

Defensively, this team has turned it around and obviously found their stride. Nick Bosa, who has 11 sacks this season, will probably have a field day against a weak Seattle offensive line which doesn’t help Wilson’s case at all. They allow the sixth least yards per game with 318.7 and just 207.3 passing yards. This will cause problems for an already struggling Seattle offense. Despite being a way better defense, they have allowed two more points than the Seahawks have, per game. They will come out firing looking to take down a lost Russell Wilson, and tie their record with them this season, 1-1.

San Francisco 49ers Depth Chart

QB: Jimmy Garoppolo
RB1: Elijah Mitchell
RB2: Jeff Wilson Jr.
WR1: Deebo Samuel
WR2: Brandon Aiyuk
WR3: Jauan Jennings
TE1: George Kittle
TE2: Ross Dwelley

Seattle Seahawks Analysis

There is a reason this team was scheduled for five primetime games this season…they were supposed to be good. They have weapons on both sides of the ball that should make them a really competitive team, but they look the worst that they have in ten years. Russell Wilson made his return from his finger injury and looks worse than he did before, so I’m starting to wonder if his finger is bothering him more than he’s letting on. His passing accuracy, which was once his signature, is completely gone. His completion percentage is still 64.9% but that is the lowest it has been since 2017. It’s not all on him though, his offensive line doesn’t exactly give him copious amounts of time to throw the ball, and has allowed 22 sacks on him over just 8 games. 

Meanwhile, the usual Metcalf-Lockett combination has been quiet this year. Lockett had some clutch catches against Washington on Monday where he had 96 receiving yards over just 3 catches. For a second we saw a glimpse of the glory days. But Metcalf, who holds the Seahawks record for most receiving yards in a season, has just 70 yards over the last three games, and has hardly been a target. He recorded ONE catch against Washington on Monday. This offense has been averaging 203.2 passing yards per game, which is among the worst in the league, and far less than the 49ers allow per game, so they will likely struggle here. Alex Collins, who has been leading their run game, has 395 rushing yards this season, after filling in for their #1 Chris Carson, who is out for the season. The Seahawks have struggled to score this season and on average score 3.5 less points than the 49ers give up.

On defense, it’s been a disaster. They are dead last in the league in yards against per game with 399, despite having one of the lowest points allowed averages in the league. They have been able to stop teams when it matters, but let them run all over the field first. Bobby Wagner is arguably the best linebacker in the league and is leading the NFL in tackles with 128 tackles. He leads the pitiful defense with the help of Jordyn Brooks who has 113 tackles.

They also have Jamal Adams and Quandre Diggs in their secondary who are solid. Again, this team has the weapons to be really good, they just aren’t.

They are lucky that Deebo Samuel is not playing this week, as this takes away a big threat in the 49ers offense, but they still have Elijah Mitchell to stop on the run game. The 49ers offense averages 365.1 yards per game, and the Seattle defense allows that, plus 35 yards, so they’ve got their work cut out for them this week. 

Seattle Seahawks Depth Chart

QB: Russell Wilson
RB1: Alex Collins
RB2: Adrian Peterson
WR1: D.K. Metcalf
WR2: Tyler Lockett
WR3: Geoff Swain
TE1: Gerald Everett
TE2: Will Dissly

San Francisco 49ers vs. Seattle Seahawks Daily Fantasy Picks

For the 49ers, Brandon Aiyuk would be a solid option considering Samuel’s absence. He’s emerged as a good #2 this year already and will definitely be their main target if they decide to throw the ball this this game given his performance and Seattle’s weak pass defense. 

Alex Collins may be a good choice for the Seahawks this week. It’s hard to rely on this version of Russell Wilson, and against a great 49ers defense, the safe bet is to keep the ball on the ground.

Mia Fowler is a graduate of Chapman University where she studied business marketing and journalism and played on the women’s soccer team. Following her 16-year journey with soccer, she started writing for Her favorite sport to watch and write about is football but she also enjoys soccer, baseball, and basketball.

Hot NFL Matchup Previews Stories