| 1 | 1 | Christian McCaffrey C. McCaffrey | 1.5 | $65 | 90 | 401 |  CAR Panthers Carolina Panthers | 1 | 13 |
| 2 | 2 | Dalvin Cook D. Cook | 2.5 | $59 | 338 | 375 |  MIN Vikings Minnesota Vikings | 1 | 7 |
| 3 | 3 | Alvin Kamara A. Kamara | 3.4 | $56 | 378 | 334 |  NO Saints New Orleans Saints | 1 | 6 |
| 4 | 4 | Derrick Henry D. Henry | 4.8 | $56 | 333 | 331 |  TEN Titans Tennessee Titans | 1 | 13 |
| 5 | 5 | Ezekiel Elliott E. Elliott | 9.4 | $47 | 224 | 320 |  DAL Cowboys Dallas Cowboys | 1 | 7 |
| 6 | 1 | Travis Kelce T. Kelce | 10.4 | $53 | 313 | 343 |  KC Chiefs Kansas City Chiefs | 1 | 12 |
| 7 | 6 | Austin Ekeler A. Ekeler | 14.4 | $39 | 165 | 316 |  LAC Chargers Los Angeles Chargers | 1 | 7 |
| 8 | 7 | Saquon Barkley S. Barkley | 5.6 | $51 | 15 | 315 |  NYG Giants New York Giants | 1 | 10 |
| 9 | 8 | Aaron Jones A. Jones | 12.4 | $40 | 259 | 298 |  GB Packers Green Bay Packers | 1 | 13 |
| 10 | 1 | Davante Adams D. Adams | 11 | $45 | 358 | 389 | GB Packers Green Bay Packers | 1 | 13 |
| 11 | 9 | Joe Mixon J. Mixon | 18.1 | $33 | 100 | 298 |  CIN Bengals Cincinnati Bengals | 1 | 10 |
| 12 | 10 | Clyde Edwards-Helaire C. Edwards-Helaire | 26.4 | $30 | 176 | 286 | KC Chiefs Kansas City Chiefs | 1 | 12 |
| 13 | 11 | Jonathan Taylor J. Taylor | 6.2 | $44 | 253 | 275 |  IND Colts Indianapolis Colts | 1 | 14 |
| 14 | 2 | Calvin Ridley C. Ridley | 22.3 | $31 | 282 | 339 |  ATL Falcons Atlanta Falcons | 1 | 6 |
| 15 | 3 | DeAndre Hopkins D. Hopkins | 15.9 | $38 | 288 | 335 |  ARI Cardinals Arizona Cardinals | 1 | 12 |
| 16 | 12 | Nick Chubb N. Chubb | 7 | $41 | 208 | 273 |  CLE Browns Cleveland Browns | 1 | 13 |
| 17 | 4 | Tyreek Hill T. Hill | 7.1 | $47 | 329 | 331 | KC Chiefs Kansas City Chiefs | 1 | 12 |
| 18 | 5 | Stefon Diggs S. Diggs | 13.1 | $43 | 329 | 324 |  BUF Bills Buffalo Bills | 1 | 7 |
| 19 | 2 | Darren Waller D. Waller | 28.7 | $24 | 279 | 242 |  LV Raiders Las Vegas Raiders | 1 | 8 |
| 20 | 6 | Keenan Allen K. Allen | 29.3 | $24 | 245 | 295 | LAC Chargers Los Angeles Chargers | 1 | 7 |
| 21 | 7 | DK Metcalf D. Metcalf | 25.4 | $22 | 271 | 288 |  SEA Seahawks Seattle Seahawks | 1 | 9 |
| 22 | 13 | Chris Carson C. Carson | 38.1 | $23 | 188 | 273 | SEA Seahawks Seattle Seahawks | 1 | 9 |
| 23 | 8 | Allen Robinson A. Robinson | 33.3 | $21 | 263 | 286 |  CHI Bears Chicago Bears | 1 | 10 |
| 24 | 9 | Justin Jefferson J. Jefferson | 21.2 | $29 | 274 | 280 | MIN Vikings Minnesota Vikings | 1 | 7 |
| 25 | 14 | D'Andre Swift D. Swift | 27.6 | $26 | 190 | 272 |  DET Lions Detroit Lions | 1 | 9 |
| 26 | 15 | Antonio Gibson A. Gibson | 23.7 | $35 | 202 | 272 |  WAS Commanders Washington Commanders | 1 | 9 |
| 27 | 10 | Terry McLaurin T. McLaurin | 31.5 | $24 | 224 | 276 | WAS Commanders Washington Commanders | 1 | 9 |
| 28 | 1 | Kyler Murray K. Murray | 39.6 | $11 | 391 | 410 | ARI Cardinals Arizona Cardinals | 1 | 12 |
| 29 | 11 | A.J. Brown A.J. Brown | 20.6 | $27 | 248 | 275 | TEN Titans Tennessee Titans | 1 | 13 |
| 30 | 12 | CeeDee Lamb C. Lamb | 47.3 | $17 | 218 | 261 | DAL Cowboys Dallas Cowboys | 2 | 7 |
| 31 | 16 | Najee Harris N. Harris | 19 | $33 | | 267 |  PIT Steelers Pittsburgh Steelers | 1 | 7 |
| 32 | 2 | Patrick Mahomes P. Mahomes | 17.5 | $27 | 380 | 405 | KC Chiefs Kansas City Chiefs | 1 | 12 |
| 33 | 3 | George Kittle G. Kittle | 23.3 | $23 | 125 | 230 |  SF 49ers San Francisco 49ers | 1 | 6 |
| 34 | 13 | Chris Godwin C. Godwin | 44.8 | $12 | 191 | 261 |  TB Buccaneers Tampa Bay Buccaneers | 2 | 9 |
| 35 | 14 | Tyler Lockett T. Lockett | 57.7 | $11 | 265 | 260 | SEA Seahawks Seattle Seahawks | 2 | 9 |
| 36 | 15 | Mike Evans M. Evans | 37.6 | $19 | 249 | 258 | TB Buccaneers Tampa Bay Buccaneers | 1 | 9 |
| 37 | 17 | David Montgomery D. Montgomery | 39.7 | $20 | 265 | 254 | CHI Bears Chicago Bears | 1 | 10 |
| 38 | 3 | Josh Allen J. Allen | 31.5 | $17 | 405 | 397 | BUF Bills Buffalo Bills | 1 | 7 |
| 39 | 17 | Robert Woods R. Woods | 50.8 | $17 | 245 | 250 |  LAR Rams Los Angeles Rams | 2 | 11 |
| 40 | 18 | Cooper Kupp C. Kupp | 46.9 | $11 | 209 | 249 | LAR Rams Los Angeles Rams | 1 | 11 |
| 41 | 4 | Lamar Jackson L. Jackson | 42.9 | $9 | 342 | 396 |  BAL Ravens Baltimore Ravens | 1 | 8 |
| 42 | 4 | T.J. Hockenson T. Hockenson | 59.6 | $7 | 175 | 210 | DET Lions Detroit Lions | 1 | 9 |
| 43 | 20 | Miles Sanders M. Sanders | 34.9 | $25 | 170 | 247 |  PHI Eagles Philadelphia Eagles | 1 | 14 |
| 44 | 19 | Diontae Johnson D. Johnson | 62.4 | $12 | 222 | 248 | PIT Steelers Pittsburgh Steelers | 1 | 7 |
| 45 | 18 | Darrell Henderson D. Henderson | 44 | $0 | 130 | 248 | LAR Rams Los Angeles Rams | 1 | 11 |
| 46 | 19 | Josh Jacobs J. Jacobs | 30.1 | $19 | 231 | 248 | LV Raiders Las Vegas Raiders | 1 | 8 |
| 47 | 5 | Mark Andrews M. Andrews | 47.2 | $11 | 170 | 209 | BAL Ravens Baltimore Ravens | 1 | 8 |
| 48 | 16 | Amari Cooper A. Cooper | 43.6 | $19 | 237 | 255 | DAL Cowboys Dallas Cowboys | 1 | 7 |
| 49 | 21 | Chase Edmonds C. Edmonds | 71.9 | $6 | 168 | 235 | ARI Cardinals Arizona Cardinals | 1 | 12 |
| 50 | 20 | Julio Jones J. Jones | 36.4 | $17 | 146 | 247 | TEN Titans Tennessee Titans | 2 | 13 |
